| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Abcb10 | Acbd5 | ENSMUSP00000075011 | ENSMUSP00000110175 | ATP-binding cassette sub-family B member 10, mitochondrial; May mediate critical mitochondrial transport functions related to heme biosynthesis; Belongs to the ABC transporter superfamily. ABCB family. Mitochondrial peptide exporter (TC 3.A.1.212) subfamily. | Acyl-CoA-binding domain-containing protein 5; Acyl-CoA binding protein which acts as the peroxisome receptor for pexophagy but is dispensable for aggrephagy and nonselective autophagy. Binds medium- and long-chain acyl-CoA esters (By similarity). | 0.890 |
| Abcb10 | Agps | ENSMUSP00000075011 | ENSMUSP00000041967 | ATP-binding cassette sub-family B member 10, mitochondrial; May mediate critical mitochondrial transport functions related to heme biosynthesis; Belongs to the ABC transporter superfamily. ABCB family. Mitochondrial peptide exporter (TC 3.A.1.212) subfamily. | Alkyldihydroxyacetonephosphate synthase, peroxisomal; Catalyzes the exchange of the acyl chain in acyl- dihydroxyacetonephosphate (acyl-DHAP) for a long chain fatty alcohol, yielding the first ether linked intermediate, i.e. alkyl- dihydroxyacetonephosphate (alkyl-DHAP), in the pathway of ether lipid biosynthesis; Belongs to the FAD-binding oxidoreductase/transferase type 4 family. | 0.859 |
| Acbd5 | Abcb10 | ENSMUSP00000110175 | ENSMUSP00000075011 | Acyl-CoA-binding domain-containing protein 5; Acyl-CoA binding protein which acts as the peroxisome receptor for pexophagy but is dispensable for aggrephagy and nonselective autophagy. Binds medium- and long-chain acyl-CoA esters (By similarity). | ATP-binding cassette sub-family B member 10, mitochondrial; May mediate critical mitochondrial transport functions related to heme biosynthesis; Belongs to the ABC transporter superfamily. ABCB family. Mitochondrial peptide exporter (TC 3.A.1.212) subfamily. | 0.890 |
| Acbd5 | Agps | ENSMUSP00000110175 | ENSMUSP00000041967 | Acyl-CoA-binding domain-containing protein 5; Acyl-CoA binding protein which acts as the peroxisome receptor for pexophagy but is dispensable for aggrephagy and nonselective autophagy. Binds medium- and long-chain acyl-CoA esters (By similarity). | Alkyldihydroxyacetonephosphate synthase, peroxisomal; Catalyzes the exchange of the acyl chain in acyl- dihydroxyacetonephosphate (acyl-DHAP) for a long chain fatty alcohol, yielding the first ether linked intermediate, i.e. alkyl- dihydroxyacetonephosphate (alkyl-DHAP), in the pathway of ether lipid biosynthesis; Belongs to the FAD-binding oxidoreductase/transferase type 4 family. | 0.919 |
| Acbd5 | Far1 | ENSMUSP00000110175 | ENSMUSP00000033018 | Acyl-CoA-binding domain-containing protein 5; Acyl-CoA binding protein which acts as the peroxisome receptor for pexophagy but is dispensable for aggrephagy and nonselective autophagy. Binds medium- and long-chain acyl-CoA esters (By similarity). | Fatty acyl-CoA reductase 1; Catalyzes the reduction of saturated and unsaturated C16 or C18 fatty acyl-CoA to fatty alcohols. It plays an essential role in the production of ether lipids/plasmalogens which synthesis requires fatty alcohols (By similarity). In parallel, it is also required for wax monoesters production since fatty alcohols also constitute a substrate for their synthesis. | 0.477 |
| Acbd5 | Gnpat | ENSMUSP00000110175 | ENSMUSP00000034466 | Acyl-CoA-binding domain-containing protein 5; Acyl-CoA binding protein which acts as the peroxisome receptor for pexophagy but is dispensable for aggrephagy and nonselective autophagy. Binds medium- and long-chain acyl-CoA esters (By similarity). | Dihydroxyacetone phosphate acyltransferase; Belongs to the GPAT/DAPAT family. | 0.553 |
| Acbd5 | Pex10 | ENSMUSP00000110175 | ENSMUSP00000099469 | Acyl-CoA-binding domain-containing protein 5; Acyl-CoA binding protein which acts as the peroxisome receptor for pexophagy but is dispensable for aggrephagy and nonselective autophagy. Binds medium- and long-chain acyl-CoA esters (By similarity). | Peroxisome biogenesis factor 10; Somewhat implicated in the biogenesis of peroxisomes. | 0.475 |
| Acbd5 | Pex14 | ENSMUSP00000110175 | ENSMUSP00000099506 | Acyl-CoA-binding domain-containing protein 5; Acyl-CoA binding protein which acts as the peroxisome receptor for pexophagy but is dispensable for aggrephagy and nonselective autophagy. Binds medium- and long-chain acyl-CoA esters (By similarity). | Peroxisomal membrane protein PEX14; Peroxisome membrane protein that is an essential component of the peroxisomal import machinery. Functions as a docking factor for the predominantly cytoplasmic PTS1 receptor (PEX5). Plays a key role for peroxisome movement through a direct interaction with tubulin. | 0.760 |
| Acbd5 | Pex5 | ENSMUSP00000110175 | ENSMUSP00000108151 | Acyl-CoA-binding domain-containing protein 5; Acyl-CoA binding protein which acts as the peroxisome receptor for pexophagy but is dispensable for aggrephagy and nonselective autophagy. Binds medium- and long-chain acyl-CoA esters (By similarity). | Peroxisomal targeting signal 1 receptor; Binds to the C-terminal PTS1-type tripeptide peroxisomal targeting signal (SKL-type) and plays an essential role in peroxisomal protein import. | 0.645 |
| Acbd5 | Pex7 | ENSMUSP00000110175 | ENSMUSP00000020182 | Acyl-CoA-binding domain-containing protein 5; Acyl-CoA binding protein which acts as the peroxisome receptor for pexophagy but is dispensable for aggrephagy and nonselective autophagy. Binds medium- and long-chain acyl-CoA esters (By similarity). | Peroxisomal targeting signal 2 receptor; Binds to the N-terminal PTS2-type peroxisomal targeting signal and plays an essential role in peroxisomal protein import. | 0.527 |
| Agps | Abcb10 | ENSMUSP00000041967 | ENSMUSP00000075011 | Alkyldihydroxyacetonephosphate synthase, peroxisomal; Catalyzes the exchange of the acyl chain in acyl- dihydroxyacetonephosphate (acyl-DHAP) for a long chain fatty alcohol, yielding the first ether linked intermediate, i.e. alkyl- dihydroxyacetonephosphate (alkyl-DHAP), in the pathway of ether lipid biosynthesis; Belongs to the FAD-binding oxidoreductase/transferase type 4 family. | ATP-binding cassette sub-family B member 10, mitochondrial; May mediate critical mitochondrial transport functions related to heme biosynthesis; Belongs to the ABC transporter superfamily. ABCB family. Mitochondrial peptide exporter (TC 3.A.1.212) subfamily. | 0.859 |
| Agps | Acbd5 | ENSMUSP00000041967 | ENSMUSP00000110175 | Alkyldihydroxyacetonephosphate synthase, peroxisomal; Catalyzes the exchange of the acyl chain in acyl- dihydroxyacetonephosphate (acyl-DHAP) for a long chain fatty alcohol, yielding the first ether linked intermediate, i.e. alkyl- dihydroxyacetonephosphate (alkyl-DHAP), in the pathway of ether lipid biosynthesis; Belongs to the FAD-binding oxidoreductase/transferase type 4 family. | Acyl-CoA-binding domain-containing protein 5; Acyl-CoA binding protein which acts as the peroxisome receptor for pexophagy but is dispensable for aggrephagy and nonselective autophagy. Binds medium- and long-chain acyl-CoA esters (By similarity). | 0.919 |
| Agps | Far1 | ENSMUSP00000041967 | ENSMUSP00000033018 | Alkyldihydroxyacetonephosphate synthase, peroxisomal; Catalyzes the exchange of the acyl chain in acyl- dihydroxyacetonephosphate (acyl-DHAP) for a long chain fatty alcohol, yielding the first ether linked intermediate, i.e. alkyl- dihydroxyacetonephosphate (alkyl-DHAP), in the pathway of ether lipid biosynthesis; Belongs to the FAD-binding oxidoreductase/transferase type 4 family. | Fatty acyl-CoA reductase 1; Catalyzes the reduction of saturated and unsaturated C16 or C18 fatty acyl-CoA to fatty alcohols. It plays an essential role in the production of ether lipids/plasmalogens which synthesis requires fatty alcohols (By similarity). In parallel, it is also required for wax monoesters production since fatty alcohols also constitute a substrate for their synthesis. | 0.894 |
| Agps | Gnpat | ENSMUSP00000041967 | ENSMUSP00000034466 | Alkyldihydroxyacetonephosphate synthase, peroxisomal; Catalyzes the exchange of the acyl chain in acyl- dihydroxyacetonephosphate (acyl-DHAP) for a long chain fatty alcohol, yielding the first ether linked intermediate, i.e. alkyl- dihydroxyacetonephosphate (alkyl-DHAP), in the pathway of ether lipid biosynthesis; Belongs to the FAD-binding oxidoreductase/transferase type 4 family. | Dihydroxyacetone phosphate acyltransferase; Belongs to the GPAT/DAPAT family. | 0.999 |
| Agps | Pex10 | ENSMUSP00000041967 | ENSMUSP00000099469 | Alkyldihydroxyacetonephosphate synthase, peroxisomal; Catalyzes the exchange of the acyl chain in acyl- dihydroxyacetonephosphate (acyl-DHAP) for a long chain fatty alcohol, yielding the first ether linked intermediate, i.e. alkyl- dihydroxyacetonephosphate (alkyl-DHAP), in the pathway of ether lipid biosynthesis; Belongs to the FAD-binding oxidoreductase/transferase type 4 family. | Peroxisome biogenesis factor 10; Somewhat implicated in the biogenesis of peroxisomes. | 0.857 |
| Agps | Pex14 | ENSMUSP00000041967 | ENSMUSP00000099506 | Alkyldihydroxyacetonephosphate synthase, peroxisomal; Catalyzes the exchange of the acyl chain in acyl- dihydroxyacetonephosphate (acyl-DHAP) for a long chain fatty alcohol, yielding the first ether linked intermediate, i.e. alkyl- dihydroxyacetonephosphate (alkyl-DHAP), in the pathway of ether lipid biosynthesis; Belongs to the FAD-binding oxidoreductase/transferase type 4 family. | Peroxisomal membrane protein PEX14; Peroxisome membrane protein that is an essential component of the peroxisomal import machinery. Functions as a docking factor for the predominantly cytoplasmic PTS1 receptor (PEX5). Plays a key role for peroxisome movement through a direct interaction with tubulin. | 0.863 |
| Agps | Pex5 | ENSMUSP00000041967 | ENSMUSP00000108151 | Alkyldihydroxyacetonephosphate synthase, peroxisomal; Catalyzes the exchange of the acyl chain in acyl- dihydroxyacetonephosphate (acyl-DHAP) for a long chain fatty alcohol, yielding the first ether linked intermediate, i.e. alkyl- dihydroxyacetonephosphate (alkyl-DHAP), in the pathway of ether lipid biosynthesis; Belongs to the FAD-binding oxidoreductase/transferase type 4 family. | Peroxisomal targeting signal 1 receptor; Binds to the C-terminal PTS1-type tripeptide peroxisomal targeting signal (SKL-type) and plays an essential role in peroxisomal protein import. | 0.944 |
| Agps | Pex7 | ENSMUSP00000041967 | ENSMUSP00000020182 | Alkyldihydroxyacetonephosphate synthase, peroxisomal; Catalyzes the exchange of the acyl chain in acyl- dihydroxyacetonephosphate (acyl-DHAP) for a long chain fatty alcohol, yielding the first ether linked intermediate, i.e. alkyl- dihydroxyacetonephosphate (alkyl-DHAP), in the pathway of ether lipid biosynthesis; Belongs to the FAD-binding oxidoreductase/transferase type 4 family. | Peroxisomal targeting signal 2 receptor; Binds to the N-terminal PTS2-type peroxisomal targeting signal and plays an essential role in peroxisomal protein import. | 0.922 |
| Agps | Scp2 | ENSMUSP00000041967 | ENSMUSP00000030340 | Alkyldihydroxyacetonephosphate synthase, peroxisomal; Catalyzes the exchange of the acyl chain in acyl- dihydroxyacetonephosphate (acyl-DHAP) for a long chain fatty alcohol, yielding the first ether linked intermediate, i.e. alkyl- dihydroxyacetonephosphate (alkyl-DHAP), in the pathway of ether lipid biosynthesis; Belongs to the FAD-binding oxidoreductase/transferase type 4 family. | Non-specific lipid-transfer protein; Mediates in vitro the transfer of all common phospholipids, cholesterol and gangliosides between membranes. May play a role in regulating steroidogenesis. | 0.865 |
| Agps | Tysnd1 | ENSMUSP00000041967 | ENSMUSP00000020284 | Alkyldihydroxyacetonephosphate synthase, peroxisomal; Catalyzes the exchange of the acyl chain in acyl- dihydroxyacetonephosphate (acyl-DHAP) for a long chain fatty alcohol, yielding the first ether linked intermediate, i.e. alkyl- dihydroxyacetonephosphate (alkyl-DHAP), in the pathway of ether lipid biosynthesis; Belongs to the FAD-binding oxidoreductase/transferase type 4 family. | Peroxisomal leader peptide-processing protease, 10 kDa form; Peroxisomal protease that mediates both the removal of the leader peptide from proteins containing a PTS2 target sequence and processes several PTS1-containing proteins. Catalyzes the processing of PTS1-proteins involved in the peroxisomal beta-oxidation of fatty acids (By similarity); Belongs to the peptidase S1B family. | 0.888 |
