node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Amph | Dner | ENSMUSP00000142766 | ENSMUSP00000042927 | Amphiphysin; May participate in mechanisms of regulated exocytosis in synapses and certain endocrine cell types. May control the properties of the membrane associated cytoskeleton (By similarity). | Delta and Notch-like epidermal growth factor-related receptor; Mediates neuron-glia interaction during astrocytogenesis. May promote differentiation of Bergmann glia during cerebellar development by activating DELTEX-dependent NOTCH1 signaling. | 0.731 |
Amph | Dpp10 | ENSMUSP00000142766 | ENSMUSP00000108225 | Amphiphysin; May participate in mechanisms of regulated exocytosis in synapses and certain endocrine cell types. May control the properties of the membrane associated cytoskeleton (By similarity). | Inactive dipeptidyl peptidase 10; Promotes cell surface expression of the potassium channel KCND2. Modulates the activity and gating characteristics of the potassium channel KCND2. Has no dipeptidyl aminopeptidase activity (Probable). | 0.658 |
Amph | Dpp6 | ENSMUSP00000142766 | ENSMUSP00000113441 | Amphiphysin; May participate in mechanisms of regulated exocytosis in synapses and certain endocrine cell types. May control the properties of the membrane associated cytoskeleton (By similarity). | Dipeptidyl aminopeptidase-like protein 6; Promotes cell surface expression of the potassium channel KCND2. Modulates the activity and gating characteristics of the potassium channel KCND2. Has no dipeptidyl aminopeptidase activity (By similarity). Belongs to the peptidase S9B family. | 0.676 |
Amph | Dpysl5 | ENSMUSP00000142766 | ENSMUSP00000110377 | Amphiphysin; May participate in mechanisms of regulated exocytosis in synapses and certain endocrine cell types. May control the properties of the membrane associated cytoskeleton (By similarity). | Dihydropyrimidinase-related protein 5; May have a function in neuronal differentiation and/or axon growth. | 0.793 |
Amph | Iglon5 | ENSMUSP00000142766 | ENSMUSP00000103608 | Amphiphysin; May participate in mechanisms of regulated exocytosis in synapses and certain endocrine cell types. May control the properties of the membrane associated cytoskeleton (By similarity). | IgLON family member 5. | 0.628 |
Amph | Lgi1 | ENSMUSP00000142766 | ENSMUSP00000143128 | Amphiphysin; May participate in mechanisms of regulated exocytosis in synapses and certain endocrine cell types. May control the properties of the membrane associated cytoskeleton (By similarity). | Leucine-rich glioma-inactivated protein 1; Regulates voltage-gated potassium channels assembled from KCNA1, KCNA4 and KCNAB1. It slows down channel inactivation by precluding channel closure mediated by the KCNAB1 subunit. Ligand for ADAM22 that positively regulates synaptic transmission mediated by AMPA-type glutamate receptors. Plays a role in suppressing the production of MMP1/3 through the phosphatidylinositol 3-kinase/ERK pathway (By similarity). | 0.753 |
Amph | Zic4 | ENSMUSP00000142766 | ENSMUSP00000134053 | Amphiphysin; May participate in mechanisms of regulated exocytosis in synapses and certain endocrine cell types. May control the properties of the membrane associated cytoskeleton (By similarity). | Zinc finger protein ZIC 4; Binds to DNA; Belongs to the GLI C2H2-type zinc-finger protein family. | 0.727 |
Cntn6 | Dner | ENSMUSP00000086623 | ENSMUSP00000042927 | Contactin-6; Contactins mediate cell surface interactions during nervous system development. Participates in oligodendrocytes generation by acting as a ligand of NOTCH1. Its association with NOTCH1 promotes NOTCH1 activation through the released notch intracellular domain (NICD) and subsequent translocation to the nucleus (By similarity). Involved in motor coordination; Belongs to the immunoglobulin superfamily. Contactin family. | Delta and Notch-like epidermal growth factor-related receptor; Mediates neuron-glia interaction during astrocytogenesis. May promote differentiation of Bergmann glia during cerebellar development by activating DELTEX-dependent NOTCH1 signaling. | 0.643 |
Cntn6 | Notch1 | ENSMUSP00000086623 | ENSMUSP00000028288 | Contactin-6; Contactins mediate cell surface interactions during nervous system development. Participates in oligodendrocytes generation by acting as a ligand of NOTCH1. Its association with NOTCH1 promotes NOTCH1 activation through the released notch intracellular domain (NICD) and subsequent translocation to the nucleus (By similarity). Involved in motor coordination; Belongs to the immunoglobulin superfamily. Contactin family. | Neurogenic locus notch homolog protein 1; Functions as a receptor for membrane-bound ligands Jagged-1 (JAG1), Jagged-2 (JAG2) and Delta-1 (DLL1) to regulate cell-fate determination. Upon ligand activation through the released notch intracellular domain (NICD) it forms a transcriptional activator complex with RBPJ/RBPSUH and activates genes of the enhancer of split locus. Affects the implementation of differentiation, proliferation and apoptotic programs. Involved in angiogenesis; negatively regulates endothelial cell proliferation and migration and angiogenic sprouting. Involved in the [...] | 0.591 |
Dner | Amph | ENSMUSP00000042927 | ENSMUSP00000142766 | Delta and Notch-like epidermal growth factor-related receptor; Mediates neuron-glia interaction during astrocytogenesis. May promote differentiation of Bergmann glia during cerebellar development by activating DELTEX-dependent NOTCH1 signaling. | Amphiphysin; May participate in mechanisms of regulated exocytosis in synapses and certain endocrine cell types. May control the properties of the membrane associated cytoskeleton (By similarity). | 0.731 |
Dner | Cntn6 | ENSMUSP00000042927 | ENSMUSP00000086623 | Delta and Notch-like epidermal growth factor-related receptor; Mediates neuron-glia interaction during astrocytogenesis. May promote differentiation of Bergmann glia during cerebellar development by activating DELTEX-dependent NOTCH1 signaling. | Contactin-6; Contactins mediate cell surface interactions during nervous system development. Participates in oligodendrocytes generation by acting as a ligand of NOTCH1. Its association with NOTCH1 promotes NOTCH1 activation through the released notch intracellular domain (NICD) and subsequent translocation to the nucleus (By similarity). Involved in motor coordination; Belongs to the immunoglobulin superfamily. Contactin family. | 0.643 |
Dner | Dpp10 | ENSMUSP00000042927 | ENSMUSP00000108225 | Delta and Notch-like epidermal growth factor-related receptor; Mediates neuron-glia interaction during astrocytogenesis. May promote differentiation of Bergmann glia during cerebellar development by activating DELTEX-dependent NOTCH1 signaling. | Inactive dipeptidyl peptidase 10; Promotes cell surface expression of the potassium channel KCND2. Modulates the activity and gating characteristics of the potassium channel KCND2. Has no dipeptidyl aminopeptidase activity (Probable). | 0.694 |
Dner | Dpp6 | ENSMUSP00000042927 | ENSMUSP00000113441 | Delta and Notch-like epidermal growth factor-related receptor; Mediates neuron-glia interaction during astrocytogenesis. May promote differentiation of Bergmann glia during cerebellar development by activating DELTEX-dependent NOTCH1 signaling. | Dipeptidyl aminopeptidase-like protein 6; Promotes cell surface expression of the potassium channel KCND2. Modulates the activity and gating characteristics of the potassium channel KCND2. Has no dipeptidyl aminopeptidase activity (By similarity). Belongs to the peptidase S9B family. | 0.702 |
Dner | Dpysl5 | ENSMUSP00000042927 | ENSMUSP00000110377 | Delta and Notch-like epidermal growth factor-related receptor; Mediates neuron-glia interaction during astrocytogenesis. May promote differentiation of Bergmann glia during cerebellar development by activating DELTEX-dependent NOTCH1 signaling. | Dihydropyrimidinase-related protein 5; May have a function in neuronal differentiation and/or axon growth. | 0.683 |
Dner | Dtx1 | ENSMUSP00000042927 | ENSMUSP00000031607 | Delta and Notch-like epidermal growth factor-related receptor; Mediates neuron-glia interaction during astrocytogenesis. May promote differentiation of Bergmann glia during cerebellar development by activating DELTEX-dependent NOTCH1 signaling. | E3 ubiquitin-protein ligase DTX1; Regulator of Notch signaling, a signaling pathway involved in cell-cell communications that regulates a broad spectrum of cell-fate determinations. Mainly acts as a positive regulator of Notch, but it also acts as a negative regulator, depending on the developmental and cell context. Mediates the antineural activity of Notch, possibly by inhibiting the transcriptional activation mediated by MATCH1. Involved in neurogenesis, lymphogenesis and myogenesis, and may also be involved in MZB (Marginal zone B) cell differentiation. Promotes B-cell development [...] | 0.714 |
Dner | Iglon5 | ENSMUSP00000042927 | ENSMUSP00000103608 | Delta and Notch-like epidermal growth factor-related receptor; Mediates neuron-glia interaction during astrocytogenesis. May promote differentiation of Bergmann glia during cerebellar development by activating DELTEX-dependent NOTCH1 signaling. | IgLON family member 5. | 0.651 |
Dner | Lgi1 | ENSMUSP00000042927 | ENSMUSP00000143128 | Delta and Notch-like epidermal growth factor-related receptor; Mediates neuron-glia interaction during astrocytogenesis. May promote differentiation of Bergmann glia during cerebellar development by activating DELTEX-dependent NOTCH1 signaling. | Leucine-rich glioma-inactivated protein 1; Regulates voltage-gated potassium channels assembled from KCNA1, KCNA4 and KCNAB1. It slows down channel inactivation by precluding channel closure mediated by the KCNAB1 subunit. Ligand for ADAM22 that positively regulates synaptic transmission mediated by AMPA-type glutamate receptors. Plays a role in suppressing the production of MMP1/3 through the phosphatidylinositol 3-kinase/ERK pathway (By similarity). | 0.666 |
Dner | Notch1 | ENSMUSP00000042927 | ENSMUSP00000028288 | Delta and Notch-like epidermal growth factor-related receptor; Mediates neuron-glia interaction during astrocytogenesis. May promote differentiation of Bergmann glia during cerebellar development by activating DELTEX-dependent NOTCH1 signaling. | Neurogenic locus notch homolog protein 1; Functions as a receptor for membrane-bound ligands Jagged-1 (JAG1), Jagged-2 (JAG2) and Delta-1 (DLL1) to regulate cell-fate determination. Upon ligand activation through the released notch intracellular domain (NICD) it forms a transcriptional activator complex with RBPJ/RBPSUH and activates genes of the enhancer of split locus. Affects the implementation of differentiation, proliferation and apoptotic programs. Involved in angiogenesis; negatively regulates endothelial cell proliferation and migration and angiogenic sprouting. Involved in the [...] | 0.788 |
Dner | Zic4 | ENSMUSP00000042927 | ENSMUSP00000134053 | Delta and Notch-like epidermal growth factor-related receptor; Mediates neuron-glia interaction during astrocytogenesis. May promote differentiation of Bergmann glia during cerebellar development by activating DELTEX-dependent NOTCH1 signaling. | Zinc finger protein ZIC 4; Binds to DNA; Belongs to the GLI C2H2-type zinc-finger protein family. | 0.762 |
Dpp10 | Amph | ENSMUSP00000108225 | ENSMUSP00000142766 | Inactive dipeptidyl peptidase 10; Promotes cell surface expression of the potassium channel KCND2. Modulates the activity and gating characteristics of the potassium channel KCND2. Has no dipeptidyl aminopeptidase activity (Probable). | Amphiphysin; May participate in mechanisms of regulated exocytosis in synapses and certain endocrine cell types. May control the properties of the membrane associated cytoskeleton (By similarity). | 0.658 |