node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Cep83 | Cnppd1 | ENSMUSP00000020212 | ENSMUSP00000132688 | Centrosomal protein of 83 kDa; Component of the distal appendage region of the centriole involved in the initiation of primary cilium assembly. May collaborate with IFT20 in the trafficking of ciliary membrane proteins from the Golgi complex to the cilium during the initiation of primary cilium assembly; Belongs to the CEP83 family. | Protein CNPPD1. | 0.444 |
Cnppd1 | Cep83 | ENSMUSP00000132688 | ENSMUSP00000020212 | Protein CNPPD1. | Centrosomal protein of 83 kDa; Component of the distal appendage region of the centriole involved in the initiation of primary cilium assembly. May collaborate with IFT20 in the trafficking of ciliary membrane proteins from the Golgi complex to the cilium during the initiation of primary cilium assembly; Belongs to the CEP83 family. | 0.444 |
Cnppd1 | Gpcpd1 | ENSMUSP00000132688 | ENSMUSP00000105769 | Protein CNPPD1. | Glycerophosphocholine phosphodiesterase GPCPD1; May be involved in the negative regulation of skeletal muscle differentiation, independently of its glycerophosphocholine phosphodiesterase activity. | 0.418 |
Cnppd1 | Lig4 | ENSMUSP00000132688 | ENSMUSP00000093130 | Protein CNPPD1. | DNA ligase 4; Efficiently joins single-strand breaks in a double-stranded polydeoxynucleotide in an ATP-dependent reaction. Involved in DNA nonhomologous end joining (NHEJ) required for double-strand break repair and V(D)J recombination. The LIG4-XRCC4 complex is responsible for the NHEJ ligation step, and XRCC4 enhances the joining activity of LIG4. Binding of the LIG4-XRCC4 complex to DNA ends is dependent on the assembly of the DNA-dependent protein kinase complex DNA-PK to these DNA ends. | 0.428 |
Cnppd1 | Mon2 | ENSMUSP00000132688 | ENSMUSP00000073462 | Protein CNPPD1. | Protein MON2 homolog; May be required for traffic between late Golgi and early endosomes; Belongs to the MON2 family. | 0.470 |
Cnppd1 | Nbeal2 | ENSMUSP00000132688 | ENSMUSP00000128586 | Protein CNPPD1. | Neurobeachin-like protein 2; Probably involved in thrombopoiesis. Plays a role in the development or secretion of alpha-granules, that contain several growth factors important for platelet biogenesis (By similarity). | 0.412 |
Cnppd1 | Slc23a3 | ENSMUSP00000132688 | ENSMUSP00000027405 | Protein CNPPD1. | Solute carrier family 23 member 3. | 0.487 |
Cnppd1 | Supv3l1 | ENSMUSP00000132688 | ENSMUSP00000020273 | Protein CNPPD1. | ATP-dependent RNA helicase SUPV3L1, mitochondrial; Major helicase player in mitochondrial RNA metabolism. Component of the mitochondrial degradosome (mtEXO) complex, that degrades 3' overhang double-stranded RNA with a 3'-to-5' directionality in an ATP-dependent manner. Involved in the degradation of non-coding mitochondrial transcripts (MT-ncRNA) and tRNA-like molecules (By similarity). ATPase and ATP-dependent multisubstrate helicase, able to unwind double-stranded (ds) DNA and RNA, and RNA/DNA heteroduplexes in the 5'-to-3' direction. Plays a role in the RNA surveillance system in m [...] | 0.518 |
Cnppd1 | Xrcc4 | ENSMUSP00000132688 | ENSMUSP00000022115 | Protein CNPPD1. | DNA repair protein XRCC4; Involved in DNA nonhomologous end joining (NHEJ) required for double-strand break repair and V(D)J recombination. Binds to DNA and to DNA ligase IV (LIG4). The LIG4-XRCC4 complex is responsible for the NHEJ ligation step, and XRCC4 enhances the joining activity of LIG4. Binding of the LIG4-XRCC4 complex to DNA ends is dependent on the assembly of the DNA-dependent protein kinase complex DNA-PK to these DNA ends (By similarity). | 0.461 |
Cnppd1 | Xrcc5 | ENSMUSP00000132688 | ENSMUSP00000027379 | Protein CNPPD1. | X-ray repair cross-complementing protein 5; Single-stranded DNA-dependent ATP-dependent helicase. Has a role in chromosome translocation. The DNA helicase II complex binds preferentially to fork-like ends of double-stranded DNA in a cell cycle-dependent manner. It works in the 3'-5' direction. Binding to DNA may be mediated by XRCC6. Involved in DNA non-homologous end joining (NHEJ) required for double-strand break repair and V(D)J recombination. The XRCC5/6 dimer acts as regulatory subunit of the DNA-dependent protein kinase complex DNA-PK by increasing the affinity of the catalytic s [...] | 0.640 |
Gpcpd1 | Cnppd1 | ENSMUSP00000105769 | ENSMUSP00000132688 | Glycerophosphocholine phosphodiesterase GPCPD1; May be involved in the negative regulation of skeletal muscle differentiation, independently of its glycerophosphocholine phosphodiesterase activity. | Protein CNPPD1. | 0.418 |
Gpcpd1 | Slc23a3 | ENSMUSP00000105769 | ENSMUSP00000027405 | Glycerophosphocholine phosphodiesterase GPCPD1; May be involved in the negative regulation of skeletal muscle differentiation, independently of its glycerophosphocholine phosphodiesterase activity. | Solute carrier family 23 member 3. | 0.414 |
Lig4 | Cnppd1 | ENSMUSP00000093130 | ENSMUSP00000132688 | DNA ligase 4; Efficiently joins single-strand breaks in a double-stranded polydeoxynucleotide in an ATP-dependent reaction. Involved in DNA nonhomologous end joining (NHEJ) required for double-strand break repair and V(D)J recombination. The LIG4-XRCC4 complex is responsible for the NHEJ ligation step, and XRCC4 enhances the joining activity of LIG4. Binding of the LIG4-XRCC4 complex to DNA ends is dependent on the assembly of the DNA-dependent protein kinase complex DNA-PK to these DNA ends. | Protein CNPPD1. | 0.428 |
Lig4 | Slc23a3 | ENSMUSP00000093130 | ENSMUSP00000027405 | DNA ligase 4; Efficiently joins single-strand breaks in a double-stranded polydeoxynucleotide in an ATP-dependent reaction. Involved in DNA nonhomologous end joining (NHEJ) required for double-strand break repair and V(D)J recombination. The LIG4-XRCC4 complex is responsible for the NHEJ ligation step, and XRCC4 enhances the joining activity of LIG4. Binding of the LIG4-XRCC4 complex to DNA ends is dependent on the assembly of the DNA-dependent protein kinase complex DNA-PK to these DNA ends. | Solute carrier family 23 member 3. | 0.428 |
Lig4 | Xrcc4 | ENSMUSP00000093130 | ENSMUSP00000022115 | DNA ligase 4; Efficiently joins single-strand breaks in a double-stranded polydeoxynucleotide in an ATP-dependent reaction. Involved in DNA nonhomologous end joining (NHEJ) required for double-strand break repair and V(D)J recombination. The LIG4-XRCC4 complex is responsible for the NHEJ ligation step, and XRCC4 enhances the joining activity of LIG4. Binding of the LIG4-XRCC4 complex to DNA ends is dependent on the assembly of the DNA-dependent protein kinase complex DNA-PK to these DNA ends. | DNA repair protein XRCC4; Involved in DNA nonhomologous end joining (NHEJ) required for double-strand break repair and V(D)J recombination. Binds to DNA and to DNA ligase IV (LIG4). The LIG4-XRCC4 complex is responsible for the NHEJ ligation step, and XRCC4 enhances the joining activity of LIG4. Binding of the LIG4-XRCC4 complex to DNA ends is dependent on the assembly of the DNA-dependent protein kinase complex DNA-PK to these DNA ends (By similarity). | 0.999 |
Lig4 | Xrcc5 | ENSMUSP00000093130 | ENSMUSP00000027379 | DNA ligase 4; Efficiently joins single-strand breaks in a double-stranded polydeoxynucleotide in an ATP-dependent reaction. Involved in DNA nonhomologous end joining (NHEJ) required for double-strand break repair and V(D)J recombination. The LIG4-XRCC4 complex is responsible for the NHEJ ligation step, and XRCC4 enhances the joining activity of LIG4. Binding of the LIG4-XRCC4 complex to DNA ends is dependent on the assembly of the DNA-dependent protein kinase complex DNA-PK to these DNA ends. | X-ray repair cross-complementing protein 5; Single-stranded DNA-dependent ATP-dependent helicase. Has a role in chromosome translocation. The DNA helicase II complex binds preferentially to fork-like ends of double-stranded DNA in a cell cycle-dependent manner. It works in the 3'-5' direction. Binding to DNA may be mediated by XRCC6. Involved in DNA non-homologous end joining (NHEJ) required for double-strand break repair and V(D)J recombination. The XRCC5/6 dimer acts as regulatory subunit of the DNA-dependent protein kinase complex DNA-PK by increasing the affinity of the catalytic s [...] | 0.997 |
Mon2 | Cnppd1 | ENSMUSP00000073462 | ENSMUSP00000132688 | Protein MON2 homolog; May be required for traffic between late Golgi and early endosomes; Belongs to the MON2 family. | Protein CNPPD1. | 0.470 |
Nbeal2 | Cnppd1 | ENSMUSP00000128586 | ENSMUSP00000132688 | Neurobeachin-like protein 2; Probably involved in thrombopoiesis. Plays a role in the development or secretion of alpha-granules, that contain several growth factors important for platelet biogenesis (By similarity). | Protein CNPPD1. | 0.412 |
Slc23a3 | Cnppd1 | ENSMUSP00000027405 | ENSMUSP00000132688 | Solute carrier family 23 member 3. | Protein CNPPD1. | 0.487 |
Slc23a3 | Gpcpd1 | ENSMUSP00000027405 | ENSMUSP00000105769 | Solute carrier family 23 member 3. | Glycerophosphocholine phosphodiesterase GPCPD1; May be involved in the negative regulation of skeletal muscle differentiation, independently of its glycerophosphocholine phosphodiesterase activity. | 0.414 |