node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Ak9 | Tcta | ENSMUSP00000134177 | ENSMUSP00000045063 | Adenylate kinase 9. | T-cell leukemia translocation-altered gene protein homolog; May be required for cellular fusion during osteoclastogenesis; Belongs to the TCTA family. | 0.450 |
Atp6v1f | Tcta | ENSMUSP00000004396 | ENSMUSP00000045063 | V-type proton ATPase subunit F; Subunit of the peripheral V1 complex of vacuolar ATPase essential for assembly or catalytic function. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. | T-cell leukemia translocation-altered gene protein homolog; May be required for cellular fusion during osteoclastogenesis; Belongs to the TCTA family. | 0.412 |
Bloc1s3 | Gpr25 | ENSMUSP00000076624 | ENSMUSP00000083583 | Biogenesis of lysosome-related organelles complex 1 subunit 3; Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO), such as platelet dense granules and melanosomes. In concert with the AP-3 complex, the BLOC-1 complex is required to target membrane protein cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. The BLOC-1 complex, in association with SNARE proteins, is also proposed to be involved in neurite extension. Plays a role in intracellular vesicle trafficking. Belongs to th [...] | Probable G-protein coupled receptor 25; Orphan receptor; Belongs to the G-protein coupled receptor 1 family. | 0.609 |
Bloc1s3 | Tcta | ENSMUSP00000076624 | ENSMUSP00000045063 | Biogenesis of lysosome-related organelles complex 1 subunit 3; Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO), such as platelet dense granules and melanosomes. In concert with the AP-3 complex, the BLOC-1 complex is required to target membrane protein cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. The BLOC-1 complex, in association with SNARE proteins, is also proposed to be involved in neurite extension. Plays a role in intracellular vesicle trafficking. Belongs to th [...] | T-cell leukemia translocation-altered gene protein homolog; May be required for cellular fusion during osteoclastogenesis; Belongs to the TCTA family. | 0.482 |
Fam102b | Tcta | ENSMUSP00000131904 | ENSMUSP00000045063 | Protein FAM102B; Belongs to the FAM102 family. | T-cell leukemia translocation-altered gene protein homolog; May be required for cellular fusion during osteoclastogenesis; Belongs to the TCTA family. | 0.477 |
Fam102b | Zfp235 | ENSMUSP00000131904 | ENSMUSP00000050803 | Protein FAM102B; Belongs to the FAM102 family. | Zinc finger protein 235. | 0.506 |
Gpr25 | Bloc1s3 | ENSMUSP00000083583 | ENSMUSP00000076624 | Probable G-protein coupled receptor 25; Orphan receptor; Belongs to the G-protein coupled receptor 1 family. | Biogenesis of lysosome-related organelles complex 1 subunit 3; Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO), such as platelet dense granules and melanosomes. In concert with the AP-3 complex, the BLOC-1 complex is required to target membrane protein cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. The BLOC-1 complex, in association with SNARE proteins, is also proposed to be involved in neurite extension. Plays a role in intracellular vesicle trafficking. Belongs to th [...] | 0.609 |
Gpr25 | Tcta | ENSMUSP00000083583 | ENSMUSP00000045063 | Probable G-protein coupled receptor 25; Orphan receptor; Belongs to the G-protein coupled receptor 1 family. | T-cell leukemia translocation-altered gene protein homolog; May be required for cellular fusion during osteoclastogenesis; Belongs to the TCTA family. | 0.588 |
Otop3 | Tcta | ENSMUSP00000019006 | ENSMUSP00000045063 | Proton channel OTOP3; Proton-selective channel that specifically transports protons into cells. Proton-selective channel activity is probably required in cell types that use changes in intracellular pH for cell signaling or to regulate biochemical or developmental processes. Belongs to the otopetrin family. | T-cell leukemia translocation-altered gene protein homolog; May be required for cellular fusion during osteoclastogenesis; Belongs to the TCTA family. | 0.543 |
Riiad1 | Tcta | ENSMUSP00000029785 | ENSMUSP00000045063 | RIIa domain-containing protein 1. | T-cell leukemia translocation-altered gene protein homolog; May be required for cellular fusion during osteoclastogenesis; Belongs to the TCTA family. | 0.531 |
Tcta | Ak9 | ENSMUSP00000045063 | ENSMUSP00000134177 | T-cell leukemia translocation-altered gene protein homolog; May be required for cellular fusion during osteoclastogenesis; Belongs to the TCTA family. | Adenylate kinase 9. | 0.450 |
Tcta | Atp6v1f | ENSMUSP00000045063 | ENSMUSP00000004396 | T-cell leukemia translocation-altered gene protein homolog; May be required for cellular fusion during osteoclastogenesis; Belongs to the TCTA family. | V-type proton ATPase subunit F; Subunit of the peripheral V1 complex of vacuolar ATPase essential for assembly or catalytic function. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. | 0.412 |
Tcta | Bloc1s3 | ENSMUSP00000045063 | ENSMUSP00000076624 | T-cell leukemia translocation-altered gene protein homolog; May be required for cellular fusion during osteoclastogenesis; Belongs to the TCTA family. | Biogenesis of lysosome-related organelles complex 1 subunit 3; Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO), such as platelet dense granules and melanosomes. In concert with the AP-3 complex, the BLOC-1 complex is required to target membrane protein cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. The BLOC-1 complex, in association with SNARE proteins, is also proposed to be involved in neurite extension. Plays a role in intracellular vesicle trafficking. Belongs to th [...] | 0.482 |
Tcta | Fam102b | ENSMUSP00000045063 | ENSMUSP00000131904 | T-cell leukemia translocation-altered gene protein homolog; May be required for cellular fusion during osteoclastogenesis; Belongs to the TCTA family. | Protein FAM102B; Belongs to the FAM102 family. | 0.477 |
Tcta | Gpr25 | ENSMUSP00000045063 | ENSMUSP00000083583 | T-cell leukemia translocation-altered gene protein homolog; May be required for cellular fusion during osteoclastogenesis; Belongs to the TCTA family. | Probable G-protein coupled receptor 25; Orphan receptor; Belongs to the G-protein coupled receptor 1 family. | 0.588 |
Tcta | Otop3 | ENSMUSP00000045063 | ENSMUSP00000019006 | T-cell leukemia translocation-altered gene protein homolog; May be required for cellular fusion during osteoclastogenesis; Belongs to the TCTA family. | Proton channel OTOP3; Proton-selective channel that specifically transports protons into cells. Proton-selective channel activity is probably required in cell types that use changes in intracellular pH for cell signaling or to regulate biochemical or developmental processes. Belongs to the otopetrin family. | 0.543 |
Tcta | Riiad1 | ENSMUSP00000045063 | ENSMUSP00000029785 | T-cell leukemia translocation-altered gene protein homolog; May be required for cellular fusion during osteoclastogenesis; Belongs to the TCTA family. | RIIa domain-containing protein 1. | 0.531 |
Tcta | Trabd2b | ENSMUSP00000045063 | ENSMUSP00000092494 | T-cell leukemia translocation-altered gene protein homolog; May be required for cellular fusion during osteoclastogenesis; Belongs to the TCTA family. | Metalloprotease TIKI2; Metalloprotease that acts as a negative regulator of the Wnt signaling pathway by mediating the cleavage of the 8 N-terminal residues of a subset of Wnt proteins. Following cleavage, Wnt proteins become oxidized and form large disulfide-bond oligomers, leading to their inactivation. Able to cleave WNT3A, WNT5, but not WNT11. Required for head formation (By similarity). | 0.436 |
Tcta | Zfp235 | ENSMUSP00000045063 | ENSMUSP00000050803 | T-cell leukemia translocation-altered gene protein homolog; May be required for cellular fusion during osteoclastogenesis; Belongs to the TCTA family. | Zinc finger protein 235. | 0.462 |
Tcta | Znrf2 | ENSMUSP00000045063 | ENSMUSP00000078795 | T-cell leukemia translocation-altered gene protein homolog; May be required for cellular fusion during osteoclastogenesis; Belongs to the TCTA family. | E3 ubiquitin-protein ligase ZNRF2; May play a role in the establishment and maintenance of neuronal transmission and plasticity via its ubiquitin ligase activity. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfer the ubiquitin to targeted substrates. | 0.452 |