Tcta protein (mouse) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Current Organism:

Mus musculus

NCBI taxonomy Id: 10090
Other names: LK3 transgenic mice, M. musculus, Mus sp. 129SV, house mouse, mouse, nude mice, transgenic mice

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structured XML interaction data, according to the 'PSI-MI' data standard

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Ak9	Tcta	ENSMUSP00000134177	ENSMUSP00000045063	Adenylate kinase 9.	T-cell leukemia translocation-altered gene protein homolog; May be required for cellular fusion during osteoclastogenesis; Belongs to the TCTA family.	0.488
Atp6v1f	Gpr25	ENSMUSP00000004396	ENSMUSP00000083583	V-type proton ATPase subunit F; Subunit of the peripheral V1 complex of vacuolar ATPase essential for assembly or catalytic function. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.	Probable G-protein coupled receptor 25; Orphan receptor; Belongs to the G-protein coupled receptor 1 family.	0.499
Atp6v1f	Tcta	ENSMUSP00000004396	ENSMUSP00000045063	V-type proton ATPase subunit F; Subunit of the peripheral V1 complex of vacuolar ATPase essential for assembly or catalytic function. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.	T-cell leukemia translocation-altered gene protein homolog; May be required for cellular fusion during osteoclastogenesis; Belongs to the TCTA family.	0.566
Bloc1s3	Gpr25	ENSMUSP00000076624	ENSMUSP00000083583	Biogenesis of lysosome-related organelles complex 1 subunit 3; Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO), such as platelet dense granules and melanosomes. In concert with the AP-3 complex, the BLOC-1 complex is required to target membrane protein cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. The BLOC-1 complex, in association with SNARE proteins, is also proposed to be involved in neurite extension. Plays a role in intracellular vesicle trafficking. Belongs to th [...]	Probable G-protein coupled receptor 25; Orphan receptor; Belongs to the G-protein coupled receptor 1 family.	0.655
Bloc1s3	Tcta	ENSMUSP00000076624	ENSMUSP00000045063	Biogenesis of lysosome-related organelles complex 1 subunit 3; Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO), such as platelet dense granules and melanosomes. In concert with the AP-3 complex, the BLOC-1 complex is required to target membrane protein cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. The BLOC-1 complex, in association with SNARE proteins, is also proposed to be involved in neurite extension. Plays a role in intracellular vesicle trafficking. Belongs to th [...]	T-cell leukemia translocation-altered gene protein homolog; May be required for cellular fusion during osteoclastogenesis; Belongs to the TCTA family.	0.533
Bnc2	Gpr25	ENSMUSP00000135375	ENSMUSP00000083583	Zinc finger protein basonuclin-2; Probable transcription factor specific for skin keratinocytes. May play a role in the differentiation of spermatozoa and oocytes.	Probable G-protein coupled receptor 25; Orphan receptor; Belongs to the G-protein coupled receptor 1 family.	0.434
Bnc2	Tcta	ENSMUSP00000135375	ENSMUSP00000045063	Zinc finger protein basonuclin-2; Probable transcription factor specific for skin keratinocytes. May play a role in the differentiation of spermatozoa and oocytes.	T-cell leukemia translocation-altered gene protein homolog; May be required for cellular fusion during osteoclastogenesis; Belongs to the TCTA family.	0.445
Gpr25	Atp6v1f	ENSMUSP00000083583	ENSMUSP00000004396	Probable G-protein coupled receptor 25; Orphan receptor; Belongs to the G-protein coupled receptor 1 family.	V-type proton ATPase subunit F; Subunit of the peripheral V1 complex of vacuolar ATPase essential for assembly or catalytic function. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.	0.499
Gpr25	Bloc1s3	ENSMUSP00000083583	ENSMUSP00000076624	Probable G-protein coupled receptor 25; Orphan receptor; Belongs to the G-protein coupled receptor 1 family.	Biogenesis of lysosome-related organelles complex 1 subunit 3; Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO), such as platelet dense granules and melanosomes. In concert with the AP-3 complex, the BLOC-1 complex is required to target membrane protein cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. The BLOC-1 complex, in association with SNARE proteins, is also proposed to be involved in neurite extension. Plays a role in intracellular vesicle trafficking. Belongs to th [...]	0.655
Gpr25	Bnc2	ENSMUSP00000083583	ENSMUSP00000135375	Probable G-protein coupled receptor 25; Orphan receptor; Belongs to the G-protein coupled receptor 1 family.	Zinc finger protein basonuclin-2; Probable transcription factor specific for skin keratinocytes. May play a role in the differentiation of spermatozoa and oocytes.	0.434
Gpr25	Tcta	ENSMUSP00000083583	ENSMUSP00000045063	Probable G-protein coupled receptor 25; Orphan receptor; Belongs to the G-protein coupled receptor 1 family.	T-cell leukemia translocation-altered gene protein homolog; May be required for cellular fusion during osteoclastogenesis; Belongs to the TCTA family.	0.584
Gpr25	Trappc6b	ENSMUSP00000083583	ENSMUSP00000021380	Probable G-protein coupled receptor 25; Orphan receptor; Belongs to the G-protein coupled receptor 1 family.	Trafficking protein particle complex subunit 6B; Component of a transport protein particle (TRAPP) complex that may function in specific stages of inter-organelle traffic (By similarity). Specifically involved in the early development of neural circuitry, likely by controlling the frequency and amplitude of intracellular calcium transients implicated in the regulation of neuron differentiation and survival (By similarity). Belongs to the TRAPP small subunits family. BET3 subfamily.	0.433
Otop3	Tcta	ENSMUSP00000019006	ENSMUSP00000045063	Proton channel OTOP3; Proton-selective channel that specifically transports protons into cells. Proton-selective channel activity is probably required in cell types that use changes in intracellular pH for cell signaling or to regulate biochemical or developmental processes. Belongs to the otopetrin family.	T-cell leukemia translocation-altered gene protein homolog; May be required for cellular fusion during osteoclastogenesis; Belongs to the TCTA family.	0.484
Ppic	Tcta	ENSMUSP00000025419	ENSMUSP00000045063	Peptidyl-prolyl cis-trans isomerase C; PPIase that catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and may therefore assist protein folding.	T-cell leukemia translocation-altered gene protein homolog; May be required for cellular fusion during osteoclastogenesis; Belongs to the TCTA family.	0.510
Tcta	Ak9	ENSMUSP00000045063	ENSMUSP00000134177	T-cell leukemia translocation-altered gene protein homolog; May be required for cellular fusion during osteoclastogenesis; Belongs to the TCTA family.	Adenylate kinase 9.	0.488
Tcta	Atp6v1f	ENSMUSP00000045063	ENSMUSP00000004396	T-cell leukemia translocation-altered gene protein homolog; May be required for cellular fusion during osteoclastogenesis; Belongs to the TCTA family.	V-type proton ATPase subunit F; Subunit of the peripheral V1 complex of vacuolar ATPase essential for assembly or catalytic function. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.	0.566
Tcta	Bloc1s3	ENSMUSP00000045063	ENSMUSP00000076624	T-cell leukemia translocation-altered gene protein homolog; May be required for cellular fusion during osteoclastogenesis; Belongs to the TCTA family.	Biogenesis of lysosome-related organelles complex 1 subunit 3; Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO), such as platelet dense granules and melanosomes. In concert with the AP-3 complex, the BLOC-1 complex is required to target membrane protein cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. The BLOC-1 complex, in association with SNARE proteins, is also proposed to be involved in neurite extension. Plays a role in intracellular vesicle trafficking. Belongs to th [...]	0.533
Tcta	Bnc2	ENSMUSP00000045063	ENSMUSP00000135375	T-cell leukemia translocation-altered gene protein homolog; May be required for cellular fusion during osteoclastogenesis; Belongs to the TCTA family.	Zinc finger protein basonuclin-2; Probable transcription factor specific for skin keratinocytes. May play a role in the differentiation of spermatozoa and oocytes.	0.445
Tcta	Gpr25	ENSMUSP00000045063	ENSMUSP00000083583	T-cell leukemia translocation-altered gene protein homolog; May be required for cellular fusion during osteoclastogenesis; Belongs to the TCTA family.	Probable G-protein coupled receptor 25; Orphan receptor; Belongs to the G-protein coupled receptor 1 family.	0.584
Tcta	Otop3	ENSMUSP00000045063	ENSMUSP00000019006	T-cell leukemia translocation-altered gene protein homolog; May be required for cellular fusion during osteoclastogenesis; Belongs to the TCTA family.	Proton channel OTOP3; Proton-selective channel that specifically transports protons into cells. Proton-selective channel activity is probably required in cell types that use changes in intracellular pH for cell signaling or to regulate biochemical or developmental processes. Belongs to the otopetrin family.	0.484