STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Prss40Serine protease 40; May play an important role in the sperm/egg interaction; released during the acrosome reaction; Belongs to the peptidase S1 family. (365 aa)    
Predicted Functional Partners:
4931406B18Rik
RIKEN cDNA 4931406B18 gene.
   
 
 0.725
Tmprss11c
Transmembrane protease serine 11C non-catalytic chain; Serine protease which has a preference for Arg or Lys in position P1 and uncharged residues in positions P2 and P3. Shows specificity towards FGF2 in vitro.
  
 
  
0.651
Gm4787
Predicted gene, EG214321.
      
 0.643
Cst13
Cystatin-13; May perform a specialized role during sperm development and maturation; Belongs to the cystatin family.
   
  
 0.641
Prorsd1
Prolyl-tRNA synthetase associated domain-containing protein 1.
      
 0.638
Ccdc162
Coiled-coil domain-containing protein 162.
   
  
 0.611
Clca3b
Chloride channel accessory 3B.
   
 
 0.609
Tmem198b
Transmembrane protein 198b.
      
 0.604
Smok2b
Sperm motility kinase 2B; May play a role in sperm motility, especially in the regulation of flagellar function.
      
 0.602
Purg
Purine-rich element-binding protein gamma.
      
 0.600
Your Current Organism:
Mus musculus
NCBI taxonomy Id: 10090
Other names: LK3 transgenic mice, M. musculus, Mus sp. 129SV, house mouse, mouse, nude mice, transgenic mice
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