node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Adgrl1 | Lrrc10 | ENSMUSP00000118452 | ENSMUSP00000073502 | Adhesion G protein-coupled receptor L1; Calcium-independent receptor of high affinity for alpha- latrotoxin, an excitatory neurotoxin present in black widow spider venom which triggers massive exocytosis from neurons and neuroendocrine cells. Receptor for TENM2 that mediates heterophilic synaptic cell-cell contact and postsynaptic specialization. Receptor probably implicated in the regulation of exocytosis (By similarity); Belongs to the G-protein coupled receptor 2 family. Adhesion G-protein coupled receptor (ADGR) subfamily. | Leucine-rich repeat-containing protein 10; May play important roles in cardiac development and/or cardiac function. | 0.526 |
Adgrl1 | Lrrc18 | ENSMUSP00000118452 | ENSMUSP00000041199 | Adhesion G protein-coupled receptor L1; Calcium-independent receptor of high affinity for alpha- latrotoxin, an excitatory neurotoxin present in black widow spider venom which triggers massive exocytosis from neurons and neuroendocrine cells. Receptor for TENM2 that mediates heterophilic synaptic cell-cell contact and postsynaptic specialization. Receptor probably implicated in the regulation of exocytosis (By similarity); Belongs to the G-protein coupled receptor 2 family. Adhesion G-protein coupled receptor (ADGR) subfamily. | Leucine-rich repeat-containing protein 18; May be involved in the regulation of spermatogenesis and sperm maturation. | 0.526 |
Adgrl1 | Vasn | ENSMUSP00000118452 | ENSMUSP00000045162 | Adhesion G protein-coupled receptor L1; Calcium-independent receptor of high affinity for alpha- latrotoxin, an excitatory neurotoxin present in black widow spider venom which triggers massive exocytosis from neurons and neuroendocrine cells. Receptor for TENM2 that mediates heterophilic synaptic cell-cell contact and postsynaptic specialization. Receptor probably implicated in the regulation of exocytosis (By similarity); Belongs to the G-protein coupled receptor 2 family. Adhesion G-protein coupled receptor (ADGR) subfamily. | Vasorin; May act as an inhibitor of TGF-beta signaling. | 0.531 |
Adgrl2 | Lrrc10 | ENSMUSP00000143626 | ENSMUSP00000073502 | Adhesion G protein-coupled receptor L2; Calcium-independent receptor of low affinity for alpha- latrotoxin, an excitatory neurotoxin present in black widow spider venom which triggers massive exocytosis from neurons and neuroendocrine cells. Receptor probably implicated in the regulation of exocytosis. | Leucine-rich repeat-containing protein 10; May play important roles in cardiac development and/or cardiac function. | 0.526 |
Adgrl2 | Lrrc18 | ENSMUSP00000143626 | ENSMUSP00000041199 | Adhesion G protein-coupled receptor L2; Calcium-independent receptor of low affinity for alpha- latrotoxin, an excitatory neurotoxin present in black widow spider venom which triggers massive exocytosis from neurons and neuroendocrine cells. Receptor probably implicated in the regulation of exocytosis. | Leucine-rich repeat-containing protein 18; May be involved in the regulation of spermatogenesis and sperm maturation. | 0.526 |
Adgrl2 | Vasn | ENSMUSP00000143626 | ENSMUSP00000045162 | Adhesion G protein-coupled receptor L2; Calcium-independent receptor of low affinity for alpha- latrotoxin, an excitatory neurotoxin present in black widow spider venom which triggers massive exocytosis from neurons and neuroendocrine cells. Receptor probably implicated in the regulation of exocytosis. | Vasorin; May act as an inhibitor of TGF-beta signaling. | 0.528 |
Adgrl3 | Lrrc10 | ENSMUSP00000072336 | ENSMUSP00000073502 | Adhesion G protein-coupled receptor L3; Plays a role in cell-cell adhesion and neuron guidance via its interactions with FLRT2 and FLRT3 that are expressed at the surface of adjacent cells. Plays a role in the development of glutamatergic synapses in the cortex. Important in determining the connectivity rates between the principal neurons in the cortex. | Leucine-rich repeat-containing protein 10; May play important roles in cardiac development and/or cardiac function. | 0.526 |
Adgrl3 | Lrrc18 | ENSMUSP00000072336 | ENSMUSP00000041199 | Adhesion G protein-coupled receptor L3; Plays a role in cell-cell adhesion and neuron guidance via its interactions with FLRT2 and FLRT3 that are expressed at the surface of adjacent cells. Plays a role in the development of glutamatergic synapses in the cortex. Important in determining the connectivity rates between the principal neurons in the cortex. | Leucine-rich repeat-containing protein 18; May be involved in the regulation of spermatogenesis and sperm maturation. | 0.526 |
Adgrl3 | Vasn | ENSMUSP00000072336 | ENSMUSP00000045162 | Adhesion G protein-coupled receptor L3; Plays a role in cell-cell adhesion and neuron guidance via its interactions with FLRT2 and FLRT3 that are expressed at the surface of adjacent cells. Plays a role in the development of glutamatergic synapses in the cortex. Important in determining the connectivity rates between the principal neurons in the cortex. | Vasorin; May act as an inhibitor of TGF-beta signaling. | 0.528 |
Lrrc10 | Adgrl1 | ENSMUSP00000073502 | ENSMUSP00000118452 | Leucine-rich repeat-containing protein 10; May play important roles in cardiac development and/or cardiac function. | Adhesion G protein-coupled receptor L1; Calcium-independent receptor of high affinity for alpha- latrotoxin, an excitatory neurotoxin present in black widow spider venom which triggers massive exocytosis from neurons and neuroendocrine cells. Receptor for TENM2 that mediates heterophilic synaptic cell-cell contact and postsynaptic specialization. Receptor probably implicated in the regulation of exocytosis (By similarity); Belongs to the G-protein coupled receptor 2 family. Adhesion G-protein coupled receptor (ADGR) subfamily. | 0.526 |
Lrrc10 | Adgrl2 | ENSMUSP00000073502 | ENSMUSP00000143626 | Leucine-rich repeat-containing protein 10; May play important roles in cardiac development and/or cardiac function. | Adhesion G protein-coupled receptor L2; Calcium-independent receptor of low affinity for alpha- latrotoxin, an excitatory neurotoxin present in black widow spider venom which triggers massive exocytosis from neurons and neuroendocrine cells. Receptor probably implicated in the regulation of exocytosis. | 0.526 |
Lrrc10 | Adgrl3 | ENSMUSP00000073502 | ENSMUSP00000072336 | Leucine-rich repeat-containing protein 10; May play important roles in cardiac development and/or cardiac function. | Adhesion G protein-coupled receptor L3; Plays a role in cell-cell adhesion and neuron guidance via its interactions with FLRT2 and FLRT3 that are expressed at the surface of adjacent cells. Plays a role in the development of glutamatergic synapses in the cortex. Important in determining the connectivity rates between the principal neurons in the cortex. | 0.526 |
Lrrc10 | Vasn | ENSMUSP00000073502 | ENSMUSP00000045162 | Leucine-rich repeat-containing protein 10; May play important roles in cardiac development and/or cardiac function. | Vasorin; May act as an inhibitor of TGF-beta signaling. | 0.450 |
Lrrc18 | Adgrl1 | ENSMUSP00000041199 | ENSMUSP00000118452 | Leucine-rich repeat-containing protein 18; May be involved in the regulation of spermatogenesis and sperm maturation. | Adhesion G protein-coupled receptor L1; Calcium-independent receptor of high affinity for alpha- latrotoxin, an excitatory neurotoxin present in black widow spider venom which triggers massive exocytosis from neurons and neuroendocrine cells. Receptor for TENM2 that mediates heterophilic synaptic cell-cell contact and postsynaptic specialization. Receptor probably implicated in the regulation of exocytosis (By similarity); Belongs to the G-protein coupled receptor 2 family. Adhesion G-protein coupled receptor (ADGR) subfamily. | 0.526 |
Lrrc18 | Adgrl2 | ENSMUSP00000041199 | ENSMUSP00000143626 | Leucine-rich repeat-containing protein 18; May be involved in the regulation of spermatogenesis and sperm maturation. | Adhesion G protein-coupled receptor L2; Calcium-independent receptor of low affinity for alpha- latrotoxin, an excitatory neurotoxin present in black widow spider venom which triggers massive exocytosis from neurons and neuroendocrine cells. Receptor probably implicated in the regulation of exocytosis. | 0.526 |
Lrrc18 | Adgrl3 | ENSMUSP00000041199 | ENSMUSP00000072336 | Leucine-rich repeat-containing protein 18; May be involved in the regulation of spermatogenesis and sperm maturation. | Adhesion G protein-coupled receptor L3; Plays a role in cell-cell adhesion and neuron guidance via its interactions with FLRT2 and FLRT3 that are expressed at the surface of adjacent cells. Plays a role in the development of glutamatergic synapses in the cortex. Important in determining the connectivity rates between the principal neurons in the cortex. | 0.526 |
Lrrc18 | Vasn | ENSMUSP00000041199 | ENSMUSP00000045162 | Leucine-rich repeat-containing protein 18; May be involved in the regulation of spermatogenesis and sperm maturation. | Vasorin; May act as an inhibitor of TGF-beta signaling. | 0.445 |
Notch1 | Tgfb2 | ENSMUSP00000028288 | ENSMUSP00000142149 | Neurogenic locus notch homolog protein 1; Functions as a receptor for membrane-bound ligands Jagged-1 (JAG1), Jagged-2 (JAG2) and Delta-1 (DLL1) to regulate cell-fate determination. Upon ligand activation through the released notch intracellular domain (NICD) it forms a transcriptional activator complex with RBPJ/RBPSUH and activates genes of the enhancer of split locus. Affects the implementation of differentiation, proliferation and apoptotic programs. Involved in angiogenesis; negatively regulates endothelial cell proliferation and migration and angiogenic sprouting. Involved in the [...] | Transforming growth factor beta-2 proprotein; Transforming growth factor beta-2 proprotein: Precursor of the Latency-associated peptide (LAP) and Transforming growth factor beta-2 (TGF-beta-2) chains, which constitute the regulatory and active subunit of TGF-beta-2, respectively. Transforming growth factor beta-2: Multifunctional protein that regulates various processes such as angiogenesis and heart development (By similarity). Activation into mature form follows different steps: following cleavage of the proprotein in the Golgi apparatus, Latency-associated peptide (LAP) and Transfor [...] | 0.402 |
Notch1 | Vasn | ENSMUSP00000028288 | ENSMUSP00000045162 | Neurogenic locus notch homolog protein 1; Functions as a receptor for membrane-bound ligands Jagged-1 (JAG1), Jagged-2 (JAG2) and Delta-1 (DLL1) to regulate cell-fate determination. Upon ligand activation through the released notch intracellular domain (NICD) it forms a transcriptional activator complex with RBPJ/RBPSUH and activates genes of the enhancer of split locus. Affects the implementation of differentiation, proliferation and apoptotic programs. Involved in angiogenesis; negatively regulates endothelial cell proliferation and migration and angiogenic sprouting. Involved in the [...] | Vasorin; May act as an inhibitor of TGF-beta signaling. | 0.525 |
Ntng1 | Vasn | ENSMUSP00000072397 | ENSMUSP00000045162 | Netrin-G1; Involved in controlling patterning and neuronal circuit formation at the laminar, cellular, subcellular and synaptic levels. Promotes neurite outgrowth of both axons and dendrites. | Vasorin; May act as an inhibitor of TGF-beta signaling. | 0.446 |