STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Hibch3-hydroxyisobutyryl-CoA hydrolase, mitochondrial; Hydrolyzes 3-hydroxyisobutyryl-CoA (HIBYL-CoA), a saline catabolite. Has high activity toward isobutyryl-CoA. Could be an isobutyryl-CoA dehydrogenase that functions in valine catabolism. Also hydrolyzes 3-hydroxypropanoyl-CoA (By similarity); Belongs to the enoyl-CoA hydratase/isomerase family. (385 aa)    
Predicted Functional Partners:
Hibadh
3-hydroxyisobutyrate dehydrogenase, mitochondrial; Belongs to the HIBADH-related family. 3-hydroxyisobutyrate dehydrogenase subfamily.
 
 
 0.998
Mrps5
28S ribosomal protein S5, mitochondrial; Belongs to the universal ribosomal protein uS5 family.
   
 
 0.981
Mrps9
28S ribosomal protein S9, mitochondrial; Belongs to the universal ribosomal protein uS9 family.
  
 
 0.977
Dap3
28S ribosomal protein S29, mitochondrial; Involved in mediating interferon-gamma-induced cell death. Belongs to the mitochondrion-specific ribosomal protein mS29 family.
   
 
 0.976
Mrps15
28S ribosomal protein S15, mitochondrial; Belongs to the universal ribosomal protein uS15 family.
   
 
 0.973
Mrps35
28S ribosomal protein S35, mitochondrial; Belongs to the mitochondrion-specific ribosomal protein mS35 family.
   
 
 0.971
Echs1
Enoyl-CoA hydratase, mitochondrial; Straight-chain enoyl-CoA thioesters from C4 up to at least C16 are processed, although with decreasing catalytic rate (By similarity). Has high substrate specificity for crotonyl-CoA and moderate specificity for acryloyl-CoA, 3-methylcrotonyl-CoA and methacrylyl-CoA. It is noteworthy that binds tiglyl-CoA, but hydrates only a small amount of this substrate (By similarity).
  
0.961
Hadh
Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial; Plays an essential role in the mitochondrial beta-oxidation of short chain fatty acids. Exerts it highest activity toward 3- hydroxybutyryl-CoA; Belongs to the 3-hydroxyacyl-CoA dehydrogenase family.
  
 
 0.947
Mrps16
28S ribosomal protein S16, mitochondrial; Belongs to the bacterial ribosomal protein bS16 family.
   
 
 0.935
Mrps10
28S ribosomal protein S10, mitochondrial; Belongs to the universal ribosomal protein uS10 family.
   
 
 0.932
Your Current Organism:
Mus musculus
NCBI taxonomy Id: 10090
Other names: LK3 transgenic mice, M. musculus, Mus sp. 129SV, house mouse, mouse, nude mice, transgenic mice
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