STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Prl3a1Prolactin family 3, subfamily a, member 1. (227 aa)    
Predicted Functional Partners:
Prlr
Prolactin receptor; This is a receptor for the anterior pituitary hormone prolactin.
   
 
 0.681
Tpbpa
Trophoblast-specific protein alpha; It may be a growth factor/hormone, perhaps involved in interaction between the maternal and fetal systems in maintenance of pregnancy.
   
  
 0.627
Pcdh12
Protocadherin-12, secreted form; Cellular adhesion molecule that may play an important role in cell-cell interactions at interendothelial junctions. Acts as a regulator of cell migration, probably via increasing cell- cell adhesion (By similarity). Promotes homotypic calcium-dependent aggregation and adhesion and clusters at intercellular junctions. Unable to bind to catenins, weakly associates with the cytoskeleton.
      
 0.604
Ctsq
Cathepsin Q; Belongs to the peptidase C1 family.
   
  
 0.483
Psg19
Pregnancy-specific glycoprotein 19.
   
  
 0.472
Psg18
Pregnancy-specific glycoprotein 18.
   
  
 0.463
Psg21
Pregnancy-specific glycoprotein 21.
   
  
 0.435
Tshb
Thyrotropin subunit beta; Indispensable for the control of thyroid structure and metabolism.
  
  
 0.430
Tpbpb
Trophoblast-specific protein beta.
   
  
 0.423
Crxos
Cone-rod homeobox, opposite strand.
   
  
 0.414
Your Current Organism:
Mus musculus
NCBI taxonomy Id: 10090
Other names: LK3 transgenic mice, M. musculus, Mus sp. 129SV, house mouse, mouse, nude mice, transgenic mice
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