node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Adgrf5 | Fndc4 | ENSMUSP00000109229 | ENSMUSP00000127404 | Adhesion G protein-coupled receptor F5; Receptor that plays a critical role in lung surfactant homeostasis. May play a role in controlling adipocyte function. | Fibronectin type III domain-containing protein 4; Acts as an anti-inflammatory factor in the intestine and colon. Binds to and acts on macrophages to downregulate pro- inflammatory gene expression. Affects key macrophage functions, including phagocytosis, by downregulating many key pathways for macrophage activation, partly via by STAT3 activation and signaling. May be required to dampen the immunological response in colitis. | 0.549 |
Atraid | Eif2b4 | ENSMUSP00000013766 | ENSMUSP00000110250 | All-trans retinoic acid-induced differentiation factor; Promotes osteoblast cell differentiation and terminal mineralization. Plays a role in inducing the cell cycle arrest via inhibiting CCND1 expression in all-trans-retinoic acid (ATRA) signal pathway (By similarity). | Translation initiation factor eIF-2B subunit delta; Catalyzes the exchange of eukaryotic initiation factor 2- bound GDP for GTP. | 0.495 |
Atraid | Fndc4 | ENSMUSP00000013766 | ENSMUSP00000127404 | All-trans retinoic acid-induced differentiation factor; Promotes osteoblast cell differentiation and terminal mineralization. Plays a role in inducing the cell cycle arrest via inhibiting CCND1 expression in all-trans-retinoic acid (ATRA) signal pathway (By similarity). | Fibronectin type III domain-containing protein 4; Acts as an anti-inflammatory factor in the intestine and colon. Binds to and acts on macrophages to downregulate pro- inflammatory gene expression. Affects key macrophage functions, including phagocytosis, by downregulating many key pathways for macrophage activation, partly via by STAT3 activation and signaling. May be required to dampen the immunological response in colitis. | 0.579 |
Ccdc121 | Eif2b4 | ENSMUSP00000052294 | ENSMUSP00000110250 | Coiled-coil domain-containing 121. | Translation initiation factor eIF-2B subunit delta; Catalyzes the exchange of eukaryotic initiation factor 2- bound GDP for GTP. | 0.434 |
Ccdc121 | Fndc4 | ENSMUSP00000052294 | ENSMUSP00000127404 | Coiled-coil domain-containing 121. | Fibronectin type III domain-containing protein 4; Acts as an anti-inflammatory factor in the intestine and colon. Binds to and acts on macrophages to downregulate pro- inflammatory gene expression. Affects key macrophage functions, including phagocytosis, by downregulating many key pathways for macrophage activation, partly via by STAT3 activation and signaling. May be required to dampen the immunological response in colitis. | 0.633 |
Ccdc121 | Ift172 | ENSMUSP00000052294 | ENSMUSP00000049335 | Coiled-coil domain-containing 121. | Intraflagellar transport protein 172 homolog; Required for the maintenance and formation of cilia. Plays an indirect role in hedgehog (Hh) signaling, cilia being required for all activity of the hedgehog pathway. | 0.477 |
Ccdc121 | Krtcap3 | ENSMUSP00000052294 | ENSMUSP00000060414 | Coiled-coil domain-containing 121. | Keratinocyte-associated protein 3; Belongs to the TMEM54 family. | 0.713 |
Ccdc121 | Supt7l | ENSMUSP00000052294 | ENSMUSP00000067337 | Coiled-coil domain-containing 121. | STAGA complex 65 subunit gamma. | 0.637 |
Ccdc121 | Zfp512 | ENSMUSP00000052294 | ENSMUSP00000075613 | Coiled-coil domain-containing 121. | Zinc finger protein 512; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family. | 0.706 |
Ccdc61 | Fndc4 | ENSMUSP00000096377 | ENSMUSP00000127404 | Coiled-coil domain-containing protein 61. | Fibronectin type III domain-containing protein 4; Acts as an anti-inflammatory factor in the intestine and colon. Binds to and acts on macrophages to downregulate pro- inflammatory gene expression. Affects key macrophage functions, including phagocytosis, by downregulating many key pathways for macrophage activation, partly via by STAT3 activation and signaling. May be required to dampen the immunological response in colitis. | 0.589 |
Eif2b4 | Atraid | ENSMUSP00000110250 | ENSMUSP00000013766 | Translation initiation factor eIF-2B subunit delta; Catalyzes the exchange of eukaryotic initiation factor 2- bound GDP for GTP. | All-trans retinoic acid-induced differentiation factor; Promotes osteoblast cell differentiation and terminal mineralization. Plays a role in inducing the cell cycle arrest via inhibiting CCND1 expression in all-trans-retinoic acid (ATRA) signal pathway (By similarity). | 0.495 |
Eif2b4 | Ccdc121 | ENSMUSP00000110250 | ENSMUSP00000052294 | Translation initiation factor eIF-2B subunit delta; Catalyzes the exchange of eukaryotic initiation factor 2- bound GDP for GTP. | Coiled-coil domain-containing 121. | 0.434 |
Eif2b4 | Fndc4 | ENSMUSP00000110250 | ENSMUSP00000127404 | Translation initiation factor eIF-2B subunit delta; Catalyzes the exchange of eukaryotic initiation factor 2- bound GDP for GTP. | Fibronectin type III domain-containing protein 4; Acts as an anti-inflammatory factor in the intestine and colon. Binds to and acts on macrophages to downregulate pro- inflammatory gene expression. Affects key macrophage functions, including phagocytosis, by downregulating many key pathways for macrophage activation, partly via by STAT3 activation and signaling. May be required to dampen the immunological response in colitis. | 0.586 |
Eif2b4 | Krtcap3 | ENSMUSP00000110250 | ENSMUSP00000060414 | Translation initiation factor eIF-2B subunit delta; Catalyzes the exchange of eukaryotic initiation factor 2- bound GDP for GTP. | Keratinocyte-associated protein 3; Belongs to the TMEM54 family. | 0.414 |
Eif2b4 | Supt7l | ENSMUSP00000110250 | ENSMUSP00000067337 | Translation initiation factor eIF-2B subunit delta; Catalyzes the exchange of eukaryotic initiation factor 2- bound GDP for GTP. | STAGA complex 65 subunit gamma. | 0.495 |
Eif2b4 | Zfp512 | ENSMUSP00000110250 | ENSMUSP00000075613 | Translation initiation factor eIF-2B subunit delta; Catalyzes the exchange of eukaryotic initiation factor 2- bound GDP for GTP. | Zinc finger protein 512; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family. | 0.460 |
Fndc4 | Adgrf5 | ENSMUSP00000127404 | ENSMUSP00000109229 | Fibronectin type III domain-containing protein 4; Acts as an anti-inflammatory factor in the intestine and colon. Binds to and acts on macrophages to downregulate pro- inflammatory gene expression. Affects key macrophage functions, including phagocytosis, by downregulating many key pathways for macrophage activation, partly via by STAT3 activation and signaling. May be required to dampen the immunological response in colitis. | Adhesion G protein-coupled receptor F5; Receptor that plays a critical role in lung surfactant homeostasis. May play a role in controlling adipocyte function. | 0.549 |
Fndc4 | Atraid | ENSMUSP00000127404 | ENSMUSP00000013766 | Fibronectin type III domain-containing protein 4; Acts as an anti-inflammatory factor in the intestine and colon. Binds to and acts on macrophages to downregulate pro- inflammatory gene expression. Affects key macrophage functions, including phagocytosis, by downregulating many key pathways for macrophage activation, partly via by STAT3 activation and signaling. May be required to dampen the immunological response in colitis. | All-trans retinoic acid-induced differentiation factor; Promotes osteoblast cell differentiation and terminal mineralization. Plays a role in inducing the cell cycle arrest via inhibiting CCND1 expression in all-trans-retinoic acid (ATRA) signal pathway (By similarity). | 0.579 |
Fndc4 | Ccdc121 | ENSMUSP00000127404 | ENSMUSP00000052294 | Fibronectin type III domain-containing protein 4; Acts as an anti-inflammatory factor in the intestine and colon. Binds to and acts on macrophages to downregulate pro- inflammatory gene expression. Affects key macrophage functions, including phagocytosis, by downregulating many key pathways for macrophage activation, partly via by STAT3 activation and signaling. May be required to dampen the immunological response in colitis. | Coiled-coil domain-containing 121. | 0.633 |
Fndc4 | Ccdc61 | ENSMUSP00000127404 | ENSMUSP00000096377 | Fibronectin type III domain-containing protein 4; Acts as an anti-inflammatory factor in the intestine and colon. Binds to and acts on macrophages to downregulate pro- inflammatory gene expression. Affects key macrophage functions, including phagocytosis, by downregulating many key pathways for macrophage activation, partly via by STAT3 activation and signaling. May be required to dampen the immunological response in colitis. | Coiled-coil domain-containing protein 61. | 0.589 |