STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Ctdspl2CTD small phosphatase-like protein 2; Probable phosphatase; Belongs to the CTDSPL2 family. (465 aa)    
Predicted Functional Partners:
Pdik1l
Serine/threonine-protein kinase PDIK1L.
   
 
 0.732
Ogfod2
2-oxoglutarate and iron-dependent oxygenase domain-containing protein 2; Belongs to the OGFOD2 family.
      
 0.683
Gtf2f1
General transcription factor IIF subunit 1; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation (By similarity); Belongs to the TFIIF alpha subunit family.
   
 
 0.677
Tmem87a
Transmembrane protein 87A; May be involved in retrograde transport from endosomes to the trans-Golgi network (TGN).
   
  
 0.617
Klhdc1
Kelch domain-containing protein 1.
   
 
 0.591
Gas2l1
GAS2-like protein 1; Seems to be involved in the cross-linking of microtubules and microfilaments (By similarity). Regulates microtubule dynamics and stability by interacting with microtubule plus-end tracking proteins, such as MAPRE1, to regulate microtubule growth along actin stress fibers (By similarity); Belongs to the GAS2 family.
    
 
 0.588
Pnpt1
Polyribonucleotide nucleotidyltransferase 1, mitochondrial; RNA-binding protein implicated in numerous RNA metabolic processes. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'-to-5' direction. Mitochondrial intermembrane factor with RNA-processing exoribonulease activity. Component of the mitochondrial degradosome (mtEXO) complex, that degrades 3' overhang double-stranded RNA with a 3'-to-5' directionality in an ATP-dependent manner. Involved in the degradation of non-coding mitochondrial transcripts (MT-ncRNA) and tRNA-like molecules (By simi [...]
   
  
 0.539
Casc4
Protein CASC4; Belongs to the GOLM1/CASC4 family.
      
 0.526
Stk35
Serine/threonine-protein kinase 35.
   
 
 0.524
Zcchc10
Zinc finger CCHC domain-containing protein 10.
   
  
 0.520
Your Current Organism:
Mus musculus
NCBI taxonomy Id: 10090
Other names: LK3 transgenic mice, M. musculus, Mus sp. 129SV, house mouse, mouse, nude mice, transgenic mice
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