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Pygm protein (mouse) - STRING interaction network
"Pygm" - Muscle glycogen phosphorylase in Mus musculus
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Edges represent protein-protein associations
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
PygmMuscle glycogen phosphorylase; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (842 aa)    
Predicted Functional Partners:
Agl
Amylo-1,6-glucosidase, 4-alpha-glucanotransferase (1532 aa)
   
 
  0.999
Gbe1
Glucan (1,4-alpha-), branching enzyme 1; Required for sufficient glycogen accumulation. The alpha 1-6 branches of glycogen play an important role in increasing the solubility of the molecule and, consequently, in reducing the osmotic pressure within cells (By similarity) (702 aa)
   
  0.998
Pgm2
Phosphoglucomutase 2; This enzyme participates in both the breakdown and synthesis of glucose (562 aa)
   
  0.994
Pgm5
Phosphoglucomutase 5; Component of adherens-type cell-cell and cell-matrix junctions. Lacks phosphoglucomutase activity (By similarity) (567 aa)
   
  0.994
Gys2
Glycogen synthase 2; Transfers the glycosyl residue from UDP-Glc to the non- reducing end of alpha-1,4-glucan (704 aa)
   
 
  0.986
Amy1
Amylase 1, salivary (511 aa)
   
  0.985
Gys1
Glycogen synthase 1, muscle; Transfers the glycosyl residue from UDP-Glc to the non- reducing end of alpha-1,4-glucan (738 aa)
   
 
  0.984
Amy2a4
Amylase 2a4 (508 aa)
   
 
  0.975
Pgm1
Phosphoglucomutase 1; Catalyzes the conversion of the nucleoside breakdown products ribose-1-phosphate and deoxyribose-1-phosphate to the corresponding 5-phosphopentoses. May also catalyze the interconversion of glucose-1-phosphate and glucose-6-phosphate. Has low glucose 1,6-bisphosphate synthase activity (By similarity) (620 aa)
   
 
  0.956
Pgm2l1
Phosphoglucomutase 2-like 1; Glucose 1,6-bisphosphate synthase using 1,3- bisphosphoglycerate as a phosphate donor and a series of 1- phosphate sugars as acceptors, including glucose 1-phosphate, mannose 1-phosphate, ribose 1-phosphate and deoxyribose 1- phosphate. 5 or 6-phosphosugars are bad substrates, with the exception of glucose 6-phosphate. Also synthesizes ribose 1,5- bisphosphate. Has only low phosphopentomutase and phosphoglucomutase activities (By similarity) (621 aa)
   
 
  0.956
Your Current Organism:
Mus musculus
NCBI taxonomy Id: 10090
Other names: LK3 transgenic mice, M. musculus, Mus, Mus muscaris, Mus musculus, Mus sp. 129SV, house mouse, mice, mouse, nude mice, transgenic mice
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