node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Ctsq | Gcm1 | ENSMUSP00000021888 | ENSMUSP00000024104 | Cathepsin Q; Belongs to the peptidase C1 family. | Chorion-specific transcription factor GCMa; Transcription factor that is necessary for placental development. Involved in the control of expression of placental growth factor (PGF) and other placenta-specific genes. Binds to the trophoblast-specific element 2 (TSE2) of the aromatase gene enhancer. Binds to the SYDE1 promoter. Has a central role in mediating the differentiation of trophoblast cells along both the villous and extravillous pathways in placental development (By similarity). | 0.742 |
Ctsq | Gcm2 | ENSMUSP00000021888 | ENSMUSP00000021791 | Cathepsin Q; Belongs to the peptidase C1 family. | Chorion-specific transcription factor GCMb; Transcription factor that binds specific sequences on gene promoters and activate their transcription. Through the regulation of gene transcription, may play a role in parathyroid gland development. | 0.716 |
Ctsq | Prl2b1 | ENSMUSP00000021888 | ENSMUSP00000100019 | Cathepsin Q; Belongs to the peptidase C1 family. | Prolactin-2B1; Belongs to the somatotropin/prolactin family. | 0.817 |
Ctsq | Prl3b1 | ENSMUSP00000021888 | ENSMUSP00000047680 | Cathepsin Q; Belongs to the peptidase C1 family. | Prolactin-3B1; Belongs to the somatotropin/prolactin family. | 0.731 |
Ctsq | Syna | ENSMUSP00000021888 | ENSMUSP00000116437 | Cathepsin Q; Belongs to the peptidase C1 family. | Transmembrane protein; This endogenous retroviral envelope protein has retained its original fusogenic properties. Together with Synb, participates in trophoblast fusion and the formation of a syncytium during placenta morphogenesis. Syna is essential for placental development and is specifically required for formation of syncytiotrophoblast layer I (SynT-I). Promotes muscle myoblast fusion. Does not have immunosuppressive activity. | 0.603 |
Ctsq | Tpbpa | ENSMUSP00000021888 | ENSMUSP00000021885 | Cathepsin Q; Belongs to the peptidase C1 family. | Trophoblast-specific protein alpha; It may be a growth factor/hormone, perhaps involved in interaction between the maternal and fetal systems in maintenance of pregnancy. | 0.492 |
Gcm1 | Ctsq | ENSMUSP00000024104 | ENSMUSP00000021888 | Chorion-specific transcription factor GCMa; Transcription factor that is necessary for placental development. Involved in the control of expression of placental growth factor (PGF) and other placenta-specific genes. Binds to the trophoblast-specific element 2 (TSE2) of the aromatase gene enhancer. Binds to the SYDE1 promoter. Has a central role in mediating the differentiation of trophoblast cells along both the villous and extravillous pathways in placental development (By similarity). | Cathepsin Q; Belongs to the peptidase C1 family. | 0.742 |
Gcm1 | Gcm2 | ENSMUSP00000024104 | ENSMUSP00000021791 | Chorion-specific transcription factor GCMa; Transcription factor that is necessary for placental development. Involved in the control of expression of placental growth factor (PGF) and other placenta-specific genes. Binds to the trophoblast-specific element 2 (TSE2) of the aromatase gene enhancer. Binds to the SYDE1 promoter. Has a central role in mediating the differentiation of trophoblast cells along both the villous and extravillous pathways in placental development (By similarity). | Chorion-specific transcription factor GCMb; Transcription factor that binds specific sequences on gene promoters and activate their transcription. Through the regulation of gene transcription, may play a role in parathyroid gland development. | 0.919 |
Gcm1 | Prl3b1 | ENSMUSP00000024104 | ENSMUSP00000047680 | Chorion-specific transcription factor GCMa; Transcription factor that is necessary for placental development. Involved in the control of expression of placental growth factor (PGF) and other placenta-specific genes. Binds to the trophoblast-specific element 2 (TSE2) of the aromatase gene enhancer. Binds to the SYDE1 promoter. Has a central role in mediating the differentiation of trophoblast cells along both the villous and extravillous pathways in placental development (By similarity). | Prolactin-3B1; Belongs to the somatotropin/prolactin family. | 0.613 |
Gcm1 | Syna | ENSMUSP00000024104 | ENSMUSP00000116437 | Chorion-specific transcription factor GCMa; Transcription factor that is necessary for placental development. Involved in the control of expression of placental growth factor (PGF) and other placenta-specific genes. Binds to the trophoblast-specific element 2 (TSE2) of the aromatase gene enhancer. Binds to the SYDE1 promoter. Has a central role in mediating the differentiation of trophoblast cells along both the villous and extravillous pathways in placental development (By similarity). | Transmembrane protein; This endogenous retroviral envelope protein has retained its original fusogenic properties. Together with Synb, participates in trophoblast fusion and the formation of a syncytium during placenta morphogenesis. Syna is essential for placental development and is specifically required for formation of syncytiotrophoblast layer I (SynT-I). Promotes muscle myoblast fusion. Does not have immunosuppressive activity. | 0.761 |
Gcm1 | Tpbpa | ENSMUSP00000024104 | ENSMUSP00000021885 | Chorion-specific transcription factor GCMa; Transcription factor that is necessary for placental development. Involved in the control of expression of placental growth factor (PGF) and other placenta-specific genes. Binds to the trophoblast-specific element 2 (TSE2) of the aromatase gene enhancer. Binds to the SYDE1 promoter. Has a central role in mediating the differentiation of trophoblast cells along both the villous and extravillous pathways in placental development (By similarity). | Trophoblast-specific protein alpha; It may be a growth factor/hormone, perhaps involved in interaction between the maternal and fetal systems in maintenance of pregnancy. | 0.793 |
Gcm1 | Tpbpb | ENSMUSP00000024104 | ENSMUSP00000079588 | Chorion-specific transcription factor GCMa; Transcription factor that is necessary for placental development. Involved in the control of expression of placental growth factor (PGF) and other placenta-specific genes. Binds to the trophoblast-specific element 2 (TSE2) of the aromatase gene enhancer. Binds to the SYDE1 promoter. Has a central role in mediating the differentiation of trophoblast cells along both the villous and extravillous pathways in placental development (By similarity). | Trophoblast-specific protein beta. | 0.435 |
Gcm2 | Ctsq | ENSMUSP00000021791 | ENSMUSP00000021888 | Chorion-specific transcription factor GCMb; Transcription factor that binds specific sequences on gene promoters and activate their transcription. Through the regulation of gene transcription, may play a role in parathyroid gland development. | Cathepsin Q; Belongs to the peptidase C1 family. | 0.716 |
Gcm2 | Gcm1 | ENSMUSP00000021791 | ENSMUSP00000024104 | Chorion-specific transcription factor GCMb; Transcription factor that binds specific sequences on gene promoters and activate their transcription. Through the regulation of gene transcription, may play a role in parathyroid gland development. | Chorion-specific transcription factor GCMa; Transcription factor that is necessary for placental development. Involved in the control of expression of placental growth factor (PGF) and other placenta-specific genes. Binds to the trophoblast-specific element 2 (TSE2) of the aromatase gene enhancer. Binds to the SYDE1 promoter. Has a central role in mediating the differentiation of trophoblast cells along both the villous and extravillous pathways in placental development (By similarity). | 0.919 |
Gcm2 | Prl3b1 | ENSMUSP00000021791 | ENSMUSP00000047680 | Chorion-specific transcription factor GCMb; Transcription factor that binds specific sequences on gene promoters and activate their transcription. Through the regulation of gene transcription, may play a role in parathyroid gland development. | Prolactin-3B1; Belongs to the somatotropin/prolactin family. | 0.583 |
Gcm2 | Syna | ENSMUSP00000021791 | ENSMUSP00000116437 | Chorion-specific transcription factor GCMb; Transcription factor that binds specific sequences on gene promoters and activate their transcription. Through the regulation of gene transcription, may play a role in parathyroid gland development. | Transmembrane protein; This endogenous retroviral envelope protein has retained its original fusogenic properties. Together with Synb, participates in trophoblast fusion and the formation of a syncytium during placenta morphogenesis. Syna is essential for placental development and is specifically required for formation of syncytiotrophoblast layer I (SynT-I). Promotes muscle myoblast fusion. Does not have immunosuppressive activity. | 0.494 |
Gcm2 | Tpbpa | ENSMUSP00000021791 | ENSMUSP00000021885 | Chorion-specific transcription factor GCMb; Transcription factor that binds specific sequences on gene promoters and activate their transcription. Through the regulation of gene transcription, may play a role in parathyroid gland development. | Trophoblast-specific protein alpha; It may be a growth factor/hormone, perhaps involved in interaction between the maternal and fetal systems in maintenance of pregnancy. | 0.775 |
Gcm2 | Tpbpb | ENSMUSP00000021791 | ENSMUSP00000079588 | Chorion-specific transcription factor GCMb; Transcription factor that binds specific sequences on gene promoters and activate their transcription. Through the regulation of gene transcription, may play a role in parathyroid gland development. | Trophoblast-specific protein beta. | 0.402 |
Phlda2 | Prl3b1 | ENSMUSP00000010904 | ENSMUSP00000047680 | Pleckstrin homology-like domain family A member 2; Plays a role in regulating placenta growth. May act via its PH domain that competes with other PH domain-containing proteins, thereby preventing their binding to membrane lipids. Belongs to the PHLDA2 family. | Prolactin-3B1; Belongs to the somatotropin/prolactin family. | 0.643 |
Phlda2 | Tpbpa | ENSMUSP00000010904 | ENSMUSP00000021885 | Pleckstrin homology-like domain family A member 2; Plays a role in regulating placenta growth. May act via its PH domain that competes with other PH domain-containing proteins, thereby preventing their binding to membrane lipids. Belongs to the PHLDA2 family. | Trophoblast-specific protein alpha; It may be a growth factor/hormone, perhaps involved in interaction between the maternal and fetal systems in maintenance of pregnancy. | 0.507 |