STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Slc22a20Solute carrier family 22 member 20; Organic anion transporter that mediates the uptake of estrone sulfate. Inhibited by probenecid, propionate, 2-methylbutyrate, 3- methylbutyrate, benzoate, heptanoate and 2-ethylhaxanoate. May act as an odorant transporter. (556 aa)    
Predicted Functional Partners:
Slc2a9
Solute carrier family 2, facilitated glucose transporter member 9; Urate transporter, which may play a role in the urate reabsorption by proximal tubules. Does not transport glucose, fructose or galactose (By similarity). Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
  
 
 0.635
C2cd4d
C2 calcium-dependent domain-containing protein 4D.
      
 0.517
4931406B18Rik
RIKEN cDNA 4931406B18 gene.
      
 0.515
Slco3a1
Solute carrier organic anion transporter family member 3A1; Mediates the Na(+)-independent transport of organic anions. Mediates transport of prostaglandins (PG) E1 and E2, thyroxine (T4), deltorphin II, BQ-123 and vasopressin.
   
  
 0.479
Tmem198b
Transmembrane protein 198b.
   
  
 0.467
Prorsd1
Prolyl-tRNA synthetase associated domain-containing protein 1.
      
 0.464
Ccdc162
Coiled-coil domain-containing protein 162.
      
 0.457
Prss40
Serine protease 40; May play an important role in the sperm/egg interaction; released during the acrosome reaction; Belongs to the peptidase S1 family.
      
 0.451
Gm4787
Predicted gene, EG214321.
      
 0.450
Slc22a18
Solute carrier family 22 member 18; May act as a transporter of organic cations based on a proton efflux antiport mechanism. May play a role in the transport of chloroquine and quinidine-related compounds in kidney (By similarity). Belongs to the major facilitator (TC 2.A.1) superfamily. Organic cation transporter (TC 2.A.1.19) family.
   
  
 0.445
Your Current Organism:
Mus musculus
NCBI taxonomy Id: 10090
Other names: LK3 transgenic mice, M. musculus, Mus sp. 129SV, house mouse, mouse, nude mice, transgenic mice
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