node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
A4gnt | Gm9573 | ENSMUSP00000045629 | ENSMUSP00000130987 | Alpha-1,4-N-acetylglucosaminyltransferase; Catalyzes the transfer of N-acetylglucosamine (GlcNAc) to core 2 branched O-glycans. Necessary for the synthesis of type III mucin which is specifically produced in the stomach, duodenum, and pancreatic duct. May protect against inflammation-associated gastric adenocarcinoma. | Predicted gene 9573. | 0.418 |
A4gnt | Muc1 | ENSMUSP00000045629 | ENSMUSP00000041963 | Alpha-1,4-N-acetylglucosaminyltransferase; Catalyzes the transfer of N-acetylglucosamine (GlcNAc) to core 2 branched O-glycans. Necessary for the synthesis of type III mucin which is specifically produced in the stomach, duodenum, and pancreatic duct. May protect against inflammation-associated gastric adenocarcinoma. | Mucin-1 subunit alpha; The alpha subunit has cell adhesive properties. Can act both as an adhesion and an anti-adhesion protein. May provide a protective layer on epithelial cells against bacterial and enzyme attack. | 0.590 |
A4gnt | Muc13 | ENSMUSP00000045629 | ENSMUSP00000110696 | Alpha-1,4-N-acetylglucosaminyltransferase; Catalyzes the transfer of N-acetylglucosamine (GlcNAc) to core 2 branched O-glycans. Necessary for the synthesis of type III mucin which is specifically produced in the stomach, duodenum, and pancreatic duct. May protect against inflammation-associated gastric adenocarcinoma. | Mucin-13; Epithelial and hemopoietic transmembrane mucin that may play a role in cell signaling. | 0.473 |
A4gnt | Muc15 | ENSMUSP00000045629 | ENSMUSP00000106645 | Alpha-1,4-N-acetylglucosaminyltransferase; Catalyzes the transfer of N-acetylglucosamine (GlcNAc) to core 2 branched O-glycans. Necessary for the synthesis of type III mucin which is specifically produced in the stomach, duodenum, and pancreatic duct. May protect against inflammation-associated gastric adenocarcinoma. | Mucin-15. | 0.436 |
A4gnt | Muc20 | ENSMUSP00000045629 | ENSMUSP00000110769 | Alpha-1,4-N-acetylglucosaminyltransferase; Catalyzes the transfer of N-acetylglucosamine (GlcNAc) to core 2 branched O-glycans. Necessary for the synthesis of type III mucin which is specifically produced in the stomach, duodenum, and pancreatic duct. May protect against inflammation-associated gastric adenocarcinoma. | Mucin-20; May regulate MET signaling cascade. Seems to decrease hepatocyte growth factor (HGF)-induced transient MAPK activation. Blocks GRB2 recruitment to MET thus suppressing the GRB2-RAS pathway. Inhibits HGF-induced proliferation of MMP1 and MMP9 expression (By similarity). | 0.632 |
A4gnt | Muc3 | ENSMUSP00000045629 | ENSMUSP00000045196 | Alpha-1,4-N-acetylglucosaminyltransferase; Catalyzes the transfer of N-acetylglucosamine (GlcNAc) to core 2 branched O-glycans. Necessary for the synthesis of type III mucin which is specifically produced in the stomach, duodenum, and pancreatic duct. May protect against inflammation-associated gastric adenocarcinoma. | Mucin 3, intestinal. | 0.403 |
A4gnt | Muc5ac | ENSMUSP00000045629 | ENSMUSP00000039699 | Alpha-1,4-N-acetylglucosaminyltransferase; Catalyzes the transfer of N-acetylglucosamine (GlcNAc) to core 2 branched O-glycans. Necessary for the synthesis of type III mucin which is specifically produced in the stomach, duodenum, and pancreatic duct. May protect against inflammation-associated gastric adenocarcinoma. | Mucin 5, subtypes A and C, tracheobronchial/gastric. | 0.627 |
A4gnt | Muc6 | ENSMUSP00000045629 | ENSMUSP00000140483 | Alpha-1,4-N-acetylglucosaminyltransferase; Catalyzes the transfer of N-acetylglucosamine (GlcNAc) to core 2 branched O-glycans. Necessary for the synthesis of type III mucin which is specifically produced in the stomach, duodenum, and pancreatic duct. May protect against inflammation-associated gastric adenocarcinoma. | Mucin-6; May provide a mechanism for modulation of the composition of the protective mucus layer related to acid secretion or the presence of bacteria and noxious agents in the lumen. Plays an important role in the cytoprotection of epithelial surfaces and are used as tumor markers in a variety of cancers. May play a role in epithelial organogenesis. | 0.859 |
Gm9573 | A4gnt | ENSMUSP00000130987 | ENSMUSP00000045629 | Predicted gene 9573. | Alpha-1,4-N-acetylglucosaminyltransferase; Catalyzes the transfer of N-acetylglucosamine (GlcNAc) to core 2 branched O-glycans. Necessary for the synthesis of type III mucin which is specifically produced in the stomach, duodenum, and pancreatic duct. May protect against inflammation-associated gastric adenocarcinoma. | 0.418 |
Gm9573 | Muc1 | ENSMUSP00000130987 | ENSMUSP00000041963 | Predicted gene 9573. | Mucin-1 subunit alpha; The alpha subunit has cell adhesive properties. Can act both as an adhesion and an anti-adhesion protein. May provide a protective layer on epithelial cells against bacterial and enzyme attack. | 0.804 |
Gm9573 | Muc13 | ENSMUSP00000130987 | ENSMUSP00000110696 | Predicted gene 9573. | Mucin-13; Epithelial and hemopoietic transmembrane mucin that may play a role in cell signaling. | 0.875 |
Gm9573 | Muc15 | ENSMUSP00000130987 | ENSMUSP00000106645 | Predicted gene 9573. | Mucin-15. | 0.902 |
Gm9573 | Muc20 | ENSMUSP00000130987 | ENSMUSP00000110769 | Predicted gene 9573. | Mucin-20; May regulate MET signaling cascade. Seems to decrease hepatocyte growth factor (HGF)-induced transient MAPK activation. Blocks GRB2 recruitment to MET thus suppressing the GRB2-RAS pathway. Inhibits HGF-induced proliferation of MMP1 and MMP9 expression (By similarity). | 0.901 |
Gm9573 | Muc3 | ENSMUSP00000130987 | ENSMUSP00000045196 | Predicted gene 9573. | Mucin 3, intestinal. | 0.601 |
Gm9573 | Muc4 | ENSMUSP00000130987 | ENSMUSP00000093813 | Predicted gene 9573. | Mucin-4. | 0.742 |
Gm9573 | Muc5ac | ENSMUSP00000130987 | ENSMUSP00000039699 | Predicted gene 9573. | Mucin 5, subtypes A and C, tracheobronchial/gastric. | 0.792 |
Gm9573 | Muc6 | ENSMUSP00000130987 | ENSMUSP00000140483 | Predicted gene 9573. | Mucin-6; May provide a mechanism for modulation of the composition of the protective mucus layer related to acid secretion or the presence of bacteria and noxious agents in the lumen. Plays an important role in the cytoprotection of epithelial surfaces and are used as tumor markers in a variety of cancers. May play a role in epithelial organogenesis. | 0.837 |
Muc1 | A4gnt | ENSMUSP00000041963 | ENSMUSP00000045629 | Mucin-1 subunit alpha; The alpha subunit has cell adhesive properties. Can act both as an adhesion and an anti-adhesion protein. May provide a protective layer on epithelial cells against bacterial and enzyme attack. | Alpha-1,4-N-acetylglucosaminyltransferase; Catalyzes the transfer of N-acetylglucosamine (GlcNAc) to core 2 branched O-glycans. Necessary for the synthesis of type III mucin which is specifically produced in the stomach, duodenum, and pancreatic duct. May protect against inflammation-associated gastric adenocarcinoma. | 0.590 |
Muc1 | Gm9573 | ENSMUSP00000041963 | ENSMUSP00000130987 | Mucin-1 subunit alpha; The alpha subunit has cell adhesive properties. Can act both as an adhesion and an anti-adhesion protein. May provide a protective layer on epithelial cells against bacterial and enzyme attack. | Predicted gene 9573. | 0.804 |
Muc1 | Muc13 | ENSMUSP00000041963 | ENSMUSP00000110696 | Mucin-1 subunit alpha; The alpha subunit has cell adhesive properties. Can act both as an adhesion and an anti-adhesion protein. May provide a protective layer on epithelial cells against bacterial and enzyme attack. | Mucin-13; Epithelial and hemopoietic transmembrane mucin that may play a role in cell signaling. | 0.918 |