node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Ap1b1 | Ascc2 | ENSMUSP00000009234 | ENSMUSP00000063272 | AP-1 complex subunit beta-1; Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the late-Golgi/trans-Golgi network (TGN) and/or endosomes. The AP complexes mediate both the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules. | Activating signal cointegrator 1 complex subunit 2; Plays a role in DNA damage repair as component of the ASCC complex. Recruits ASCC3 and ALKBH3 to sites of DNA damage by binding to polyubiquitinated proteins that have 'Lys-63'-linked polyubiquitin chains. Part of the ASC-1 complex that enhances NF-kappa-B, SRF and AP1 transactivation. | 0.422 |
Ap1b1 | Gas2l1 | ENSMUSP00000009234 | ENSMUSP00000050275 | AP-1 complex subunit beta-1; Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the late-Golgi/trans-Golgi network (TGN) and/or endosomes. The AP complexes mediate both the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules. | GAS2-like protein 1; Seems to be involved in the cross-linking of microtubules and microfilaments (By similarity). Regulates microtubule dynamics and stability by interacting with microtubule plus-end tracking proteins, such as MAPRE1, to regulate microtubule growth along actin stress fibers (By similarity); Belongs to the GAS2 family. | 0.551 |
Ap1b1 | Rasl10a | ENSMUSP00000009234 | ENSMUSP00000048453 | AP-1 complex subunit beta-1; Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the late-Golgi/trans-Golgi network (TGN) and/or endosomes. The AP complexes mediate both the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules. | Ras-like protein family member 10A; Potent inhibitor of cellular proliferation. | 0.576 |
Ascc2 | Ap1b1 | ENSMUSP00000063272 | ENSMUSP00000009234 | Activating signal cointegrator 1 complex subunit 2; Plays a role in DNA damage repair as component of the ASCC complex. Recruits ASCC3 and ALKBH3 to sites of DNA damage by binding to polyubiquitinated proteins that have 'Lys-63'-linked polyubiquitin chains. Part of the ASC-1 complex that enhances NF-kappa-B, SRF and AP1 transactivation. | AP-1 complex subunit beta-1; Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the late-Golgi/trans-Golgi network (TGN) and/or endosomes. The AP complexes mediate both the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules. | 0.422 |
Ascc2 | Gas2l1 | ENSMUSP00000063272 | ENSMUSP00000050275 | Activating signal cointegrator 1 complex subunit 2; Plays a role in DNA damage repair as component of the ASCC complex. Recruits ASCC3 and ALKBH3 to sites of DNA damage by binding to polyubiquitinated proteins that have 'Lys-63'-linked polyubiquitin chains. Part of the ASC-1 complex that enhances NF-kappa-B, SRF and AP1 transactivation. | GAS2-like protein 1; Seems to be involved in the cross-linking of microtubules and microfilaments (By similarity). Regulates microtubule dynamics and stability by interacting with microtubule plus-end tracking proteins, such as MAPRE1, to regulate microtubule growth along actin stress fibers (By similarity); Belongs to the GAS2 family. | 0.603 |
Catip | Gas2l1 | ENSMUSP00000095303 | ENSMUSP00000050275 | Ciliogenesis-associated TTC17-interacting protein; Plays a role in primary ciliogenesis by modulating actin polymerization; Belongs to the CATIP family. | GAS2-like protein 1; Seems to be involved in the cross-linking of microtubules and microfilaments (By similarity). Regulates microtubule dynamics and stability by interacting with microtubule plus-end tracking proteins, such as MAPRE1, to regulate microtubule growth along actin stress fibers (By similarity); Belongs to the GAS2 family. | 0.523 |
Crocc | Gas2l1 | ENSMUSP00000099549 | ENSMUSP00000050275 | Rootletin; Major structural component of the ciliary rootlet, a cytoskeletal-like structure in ciliated cells which originates from the basal body at the proximal end of a cilium and extends proximally toward the cell nucleus. Furthermore, is required for the correct positioning of the cilium basal body relative to the cell nucleus, to allow for ciliogenesis (By similarity). Contributes to centrosome cohesion before mitosis (By similarity). | GAS2-like protein 1; Seems to be involved in the cross-linking of microtubules and microfilaments (By similarity). Regulates microtubule dynamics and stability by interacting with microtubule plus-end tracking proteins, such as MAPRE1, to regulate microtubule growth along actin stress fibers (By similarity); Belongs to the GAS2 family. | 0.577 |
Crocc | Lrrc45 | ENSMUSP00000099549 | ENSMUSP00000026139 | Rootletin; Major structural component of the ciliary rootlet, a cytoskeletal-like structure in ciliated cells which originates from the basal body at the proximal end of a cilium and extends proximally toward the cell nucleus. Furthermore, is required for the correct positioning of the cilium basal body relative to the cell nucleus, to allow for ciliogenesis (By similarity). Contributes to centrosome cohesion before mitosis (By similarity). | Leucine-rich repeat-containing protein 45; Component of the proteinaceous fiber-like linker between two centrioles, required for centrosome cohesion. | 0.983 |
Ctdspl2 | Gas2l1 | ENSMUSP00000047543 | ENSMUSP00000050275 | CTD small phosphatase-like protein 2; Probable phosphatase; Belongs to the CTDSPL2 family. | GAS2-like protein 1; Seems to be involved in the cross-linking of microtubules and microfilaments (By similarity). Regulates microtubule dynamics and stability by interacting with microtubule plus-end tracking proteins, such as MAPRE1, to regulate microtubule growth along actin stress fibers (By similarity); Belongs to the GAS2 family. | 0.588 |
Ctdspl2 | Klhdc1 | ENSMUSP00000047543 | ENSMUSP00000068046 | CTD small phosphatase-like protein 2; Probable phosphatase; Belongs to the CTDSPL2 family. | Kelch domain-containing protein 1. | 0.591 |
Gas2l1 | Ap1b1 | ENSMUSP00000050275 | ENSMUSP00000009234 | GAS2-like protein 1; Seems to be involved in the cross-linking of microtubules and microfilaments (By similarity). Regulates microtubule dynamics and stability by interacting with microtubule plus-end tracking proteins, such as MAPRE1, to regulate microtubule growth along actin stress fibers (By similarity); Belongs to the GAS2 family. | AP-1 complex subunit beta-1; Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the late-Golgi/trans-Golgi network (TGN) and/or endosomes. The AP complexes mediate both the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules. | 0.551 |
Gas2l1 | Ascc2 | ENSMUSP00000050275 | ENSMUSP00000063272 | GAS2-like protein 1; Seems to be involved in the cross-linking of microtubules and microfilaments (By similarity). Regulates microtubule dynamics and stability by interacting with microtubule plus-end tracking proteins, such as MAPRE1, to regulate microtubule growth along actin stress fibers (By similarity); Belongs to the GAS2 family. | Activating signal cointegrator 1 complex subunit 2; Plays a role in DNA damage repair as component of the ASCC complex. Recruits ASCC3 and ALKBH3 to sites of DNA damage by binding to polyubiquitinated proteins that have 'Lys-63'-linked polyubiquitin chains. Part of the ASC-1 complex that enhances NF-kappa-B, SRF and AP1 transactivation. | 0.603 |
Gas2l1 | Catip | ENSMUSP00000050275 | ENSMUSP00000095303 | GAS2-like protein 1; Seems to be involved in the cross-linking of microtubules and microfilaments (By similarity). Regulates microtubule dynamics and stability by interacting with microtubule plus-end tracking proteins, such as MAPRE1, to regulate microtubule growth along actin stress fibers (By similarity); Belongs to the GAS2 family. | Ciliogenesis-associated TTC17-interacting protein; Plays a role in primary ciliogenesis by modulating actin polymerization; Belongs to the CATIP family. | 0.523 |
Gas2l1 | Crocc | ENSMUSP00000050275 | ENSMUSP00000099549 | GAS2-like protein 1; Seems to be involved in the cross-linking of microtubules and microfilaments (By similarity). Regulates microtubule dynamics and stability by interacting with microtubule plus-end tracking proteins, such as MAPRE1, to regulate microtubule growth along actin stress fibers (By similarity); Belongs to the GAS2 family. | Rootletin; Major structural component of the ciliary rootlet, a cytoskeletal-like structure in ciliated cells which originates from the basal body at the proximal end of a cilium and extends proximally toward the cell nucleus. Furthermore, is required for the correct positioning of the cilium basal body relative to the cell nucleus, to allow for ciliogenesis (By similarity). Contributes to centrosome cohesion before mitosis (By similarity). | 0.577 |
Gas2l1 | Ctdspl2 | ENSMUSP00000050275 | ENSMUSP00000047543 | GAS2-like protein 1; Seems to be involved in the cross-linking of microtubules and microfilaments (By similarity). Regulates microtubule dynamics and stability by interacting with microtubule plus-end tracking proteins, such as MAPRE1, to regulate microtubule growth along actin stress fibers (By similarity); Belongs to the GAS2 family. | CTD small phosphatase-like protein 2; Probable phosphatase; Belongs to the CTDSPL2 family. | 0.588 |
Gas2l1 | Klhdc1 | ENSMUSP00000050275 | ENSMUSP00000068046 | GAS2-like protein 1; Seems to be involved in the cross-linking of microtubules and microfilaments (By similarity). Regulates microtubule dynamics and stability by interacting with microtubule plus-end tracking proteins, such as MAPRE1, to regulate microtubule growth along actin stress fibers (By similarity); Belongs to the GAS2 family. | Kelch domain-containing protein 1. | 0.602 |
Gas2l1 | Lrrc45 | ENSMUSP00000050275 | ENSMUSP00000026139 | GAS2-like protein 1; Seems to be involved in the cross-linking of microtubules and microfilaments (By similarity). Regulates microtubule dynamics and stability by interacting with microtubule plus-end tracking proteins, such as MAPRE1, to regulate microtubule growth along actin stress fibers (By similarity); Belongs to the GAS2 family. | Leucine-rich repeat-containing protein 45; Component of the proteinaceous fiber-like linker between two centrioles, required for centrosome cohesion. | 0.649 |
Gas2l1 | Mapre3 | ENSMUSP00000050275 | ENSMUSP00000031058 | GAS2-like protein 1; Seems to be involved in the cross-linking of microtubules and microfilaments (By similarity). Regulates microtubule dynamics and stability by interacting with microtubule plus-end tracking proteins, such as MAPRE1, to regulate microtubule growth along actin stress fibers (By similarity); Belongs to the GAS2 family. | Microtubule-associated protein RP/EB family member 3; Plus-end tracking protein (+TIP) that binds to the plus-end of microtubules and regulates the dynamics of the microtubule cytoskeleton. Promotes microtubule growth. May be involved in spindle function by stabilizing microtubules and anchoring them at centrosomes. Also acts as a regulator of minus-end microtubule organization: interacts with the complex formed by AKAP9 and PDE4DIP, leading to recruit CAMSAP2 to the Golgi apparatus, thereby tethering non- centrosomal minus-end microtubules to the Golgi, an important step for polarized [...] | 0.608 |
Gas2l1 | Mrps5 | ENSMUSP00000050275 | ENSMUSP00000028852 | GAS2-like protein 1; Seems to be involved in the cross-linking of microtubules and microfilaments (By similarity). Regulates microtubule dynamics and stability by interacting with microtubule plus-end tracking proteins, such as MAPRE1, to regulate microtubule growth along actin stress fibers (By similarity); Belongs to the GAS2 family. | 28S ribosomal protein S5, mitochondrial; Belongs to the universal ribosomal protein uS5 family. | 0.640 |
Gas2l1 | Rasl10a | ENSMUSP00000050275 | ENSMUSP00000048453 | GAS2-like protein 1; Seems to be involved in the cross-linking of microtubules and microfilaments (By similarity). Regulates microtubule dynamics and stability by interacting with microtubule plus-end tracking proteins, such as MAPRE1, to regulate microtubule growth along actin stress fibers (By similarity); Belongs to the GAS2 family. | Ras-like protein family member 10A; Potent inhibitor of cellular proliferation. | 0.684 |