node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Atl1 | Ckap4 | ENSMUSP00000021466 | ENSMUSP00000050336 | Atlastin-1; GTPase tethering membranes through formation of trans- homooligomers and mediating homotypic fusion of endoplasmic reticulum membranes. Functions in endoplasmic reticulum tubular network biogenesis. May also regulate Golgi biogenesis. May regulate axonal development. | Cytoskeleton-associated protein 4; High-affinity epithelial cell surface receptor for APF. | 0.646 |
Atl1 | Ktn1 | ENSMUSP00000021466 | ENSMUSP00000140324 | Atlastin-1; GTPase tethering membranes through formation of trans- homooligomers and mediating homotypic fusion of endoplasmic reticulum membranes. Functions in endoplasmic reticulum tubular network biogenesis. May also regulate Golgi biogenesis. May regulate axonal development. | Kinectin; Receptor for kinesin thus involved in kinesin-driven vesicle motility. Accumulates in integrin-based adhesion complexes (IAC) upon integrin aggregation by fibronectin (By similarity). | 0.491 |
Atl1 | Reep5 | ENSMUSP00000021466 | ENSMUSP00000006027 | Atlastin-1; GTPase tethering membranes through formation of trans- homooligomers and mediating homotypic fusion of endoplasmic reticulum membranes. Functions in endoplasmic reticulum tubular network biogenesis. May also regulate Golgi biogenesis. May regulate axonal development. | Receptor expression-enhancing protein 5; May promote functional cell surface expression of olfactory receptors; Belongs to the DP1 family. | 0.715 |
Atl2 | Ckap4 | ENSMUSP00000064758 | ENSMUSP00000050336 | Atlastin-2; GTPase tethering membranes through formation of trans- homooligomers and mediating homotypic fusion of endoplasmic reticulum membranes. Functions in endoplasmic reticulum tubular network biogenesis; Belongs to the TRAFAC class dynamin-like GTPase superfamily. GB1/RHD3-type GTPase family. GB1 subfamily. | Cytoskeleton-associated protein 4; High-affinity epithelial cell surface receptor for APF. | 0.610 |
Atl2 | Ktn1 | ENSMUSP00000064758 | ENSMUSP00000140324 | Atlastin-2; GTPase tethering membranes through formation of trans- homooligomers and mediating homotypic fusion of endoplasmic reticulum membranes. Functions in endoplasmic reticulum tubular network biogenesis; Belongs to the TRAFAC class dynamin-like GTPase superfamily. GB1/RHD3-type GTPase family. GB1 subfamily. | Kinectin; Receptor for kinesin thus involved in kinesin-driven vesicle motility. Accumulates in integrin-based adhesion complexes (IAC) upon integrin aggregation by fibronectin (By similarity). | 0.496 |
Atl2 | Reep5 | ENSMUSP00000064758 | ENSMUSP00000006027 | Atlastin-2; GTPase tethering membranes through formation of trans- homooligomers and mediating homotypic fusion of endoplasmic reticulum membranes. Functions in endoplasmic reticulum tubular network biogenesis; Belongs to the TRAFAC class dynamin-like GTPase superfamily. GB1/RHD3-type GTPase family. GB1 subfamily. | Receptor expression-enhancing protein 5; May promote functional cell surface expression of olfactory receptors; Belongs to the DP1 family. | 0.676 |
Atl3 | Ckap4 | ENSMUSP00000025668 | ENSMUSP00000050336 | Atlastin-3; GTPase tethering membranes through formation of trans- homooligomers and mediating homotypic fusion of endoplasmic reticulum membranes. Functions in endoplasmic reticulum tubular network biogenesis (By similarity); Belongs to the TRAFAC class dynamin-like GTPase superfamily. GB1/RHD3-type GTPase family. GB1 subfamily. | Cytoskeleton-associated protein 4; High-affinity epithelial cell surface receptor for APF. | 0.649 |
Atl3 | Ktn1 | ENSMUSP00000025668 | ENSMUSP00000140324 | Atlastin-3; GTPase tethering membranes through formation of trans- homooligomers and mediating homotypic fusion of endoplasmic reticulum membranes. Functions in endoplasmic reticulum tubular network biogenesis (By similarity); Belongs to the TRAFAC class dynamin-like GTPase superfamily. GB1/RHD3-type GTPase family. GB1 subfamily. | Kinectin; Receptor for kinesin thus involved in kinesin-driven vesicle motility. Accumulates in integrin-based adhesion complexes (IAC) upon integrin aggregation by fibronectin (By similarity). | 0.492 |
Atl3 | Reep5 | ENSMUSP00000025668 | ENSMUSP00000006027 | Atlastin-3; GTPase tethering membranes through formation of trans- homooligomers and mediating homotypic fusion of endoplasmic reticulum membranes. Functions in endoplasmic reticulum tubular network biogenesis (By similarity); Belongs to the TRAFAC class dynamin-like GTPase superfamily. GB1/RHD3-type GTPase family. GB1 subfamily. | Receptor expression-enhancing protein 5; May promote functional cell surface expression of olfactory receptors; Belongs to the DP1 family. | 0.689 |
Ckap4 | Atl1 | ENSMUSP00000050336 | ENSMUSP00000021466 | Cytoskeleton-associated protein 4; High-affinity epithelial cell surface receptor for APF. | Atlastin-1; GTPase tethering membranes through formation of trans- homooligomers and mediating homotypic fusion of endoplasmic reticulum membranes. Functions in endoplasmic reticulum tubular network biogenesis. May also regulate Golgi biogenesis. May regulate axonal development. | 0.646 |
Ckap4 | Atl2 | ENSMUSP00000050336 | ENSMUSP00000064758 | Cytoskeleton-associated protein 4; High-affinity epithelial cell surface receptor for APF. | Atlastin-2; GTPase tethering membranes through formation of trans- homooligomers and mediating homotypic fusion of endoplasmic reticulum membranes. Functions in endoplasmic reticulum tubular network biogenesis; Belongs to the TRAFAC class dynamin-like GTPase superfamily. GB1/RHD3-type GTPase family. GB1 subfamily. | 0.610 |
Ckap4 | Atl3 | ENSMUSP00000050336 | ENSMUSP00000025668 | Cytoskeleton-associated protein 4; High-affinity epithelial cell surface receptor for APF. | Atlastin-3; GTPase tethering membranes through formation of trans- homooligomers and mediating homotypic fusion of endoplasmic reticulum membranes. Functions in endoplasmic reticulum tubular network biogenesis (By similarity); Belongs to the TRAFAC class dynamin-like GTPase superfamily. GB1/RHD3-type GTPase family. GB1 subfamily. | 0.649 |
Ckap4 | Dkk1 | ENSMUSP00000050336 | ENSMUSP00000025803 | Cytoskeleton-associated protein 4; High-affinity epithelial cell surface receptor for APF. | Dickkopf-related protein 1; Antagonizes canonical Wnt signaling by inhibiting LRP5/6 interaction with Wnt and by forming a ternary complex with the transmembrane protein KREMEN that promotes internalization of LRP5/6. Inhibits the pro-apoptotic function of KREMEN1 in a Wnt-independent manner, and has anti-apoptotic activity. Plays a role in limb development; attenuates Wnt signaling in the developing limb to allow normal limb patterning ; Belongs to the dickkopf family. | 0.962 |
Ckap4 | Ktn1 | ENSMUSP00000050336 | ENSMUSP00000140324 | Cytoskeleton-associated protein 4; High-affinity epithelial cell surface receptor for APF. | Kinectin; Receptor for kinesin thus involved in kinesin-driven vesicle motility. Accumulates in integrin-based adhesion complexes (IAC) upon integrin aggregation by fibronectin (By similarity). | 0.666 |
Ckap4 | Reep5 | ENSMUSP00000050336 | ENSMUSP00000006027 | Cytoskeleton-associated protein 4; High-affinity epithelial cell surface receptor for APF. | Receptor expression-enhancing protein 5; May promote functional cell surface expression of olfactory receptors; Belongs to the DP1 family. | 0.617 |
Ckap4 | Rnd3 | ENSMUSP00000050336 | ENSMUSP00000017288 | Cytoskeleton-associated protein 4; High-affinity epithelial cell surface receptor for APF. | Rho-related GTP-binding protein RhoE; Binds GTP but lacks intrinsic GTPase activity and is resistant to Rho-specific GTPase-activating proteins. | 0.583 |
Ckap4 | Sftpa1 | ENSMUSP00000050336 | ENSMUSP00000129696 | Cytoskeleton-associated protein 4; High-affinity epithelial cell surface receptor for APF. | Pulmonary surfactant-associated protein A; In presence of calcium ions, it binds to surfactant phospholipids and contributes to lower the surface tension at the air- liquid interface in the alveoli of the mammalian lung and is essential for normal respiration. Enhances the expression of MYO18A/SP-R210 on alveolar macrophages ; Belongs to the SFTPA family. | 0.724 |
Ckap4 | Tmem214 | ENSMUSP00000050336 | ENSMUSP00000144615 | Cytoskeleton-associated protein 4; High-affinity epithelial cell surface receptor for APF. | Transmembrane protein 214; Critical mediator, in cooperation with CASP4, of endoplasmic reticulum-stress induced apoptosis. Required or the activation of CASP4 following endoplasmic reticulum stress (By similarity); Belongs to the TMEM214 family. | 0.654 |
Ckap4 | Zdhhc2 | ENSMUSP00000050336 | ENSMUSP00000041727 | Cytoskeleton-associated protein 4; High-affinity epithelial cell surface receptor for APF. | Palmitoyltransferase ZDHHC2; Palmitoyltransferase specific for GAP43 and DLG4/PSD95. | 0.922 |
Dkk1 | Ckap4 | ENSMUSP00000025803 | ENSMUSP00000050336 | Dickkopf-related protein 1; Antagonizes canonical Wnt signaling by inhibiting LRP5/6 interaction with Wnt and by forming a ternary complex with the transmembrane protein KREMEN that promotes internalization of LRP5/6. Inhibits the pro-apoptotic function of KREMEN1 in a Wnt-independent manner, and has anti-apoptotic activity. Plays a role in limb development; attenuates Wnt signaling in the developing limb to allow normal limb patterning ; Belongs to the dickkopf family. | Cytoskeleton-associated protein 4; High-affinity epithelial cell surface receptor for APF. | 0.962 |