STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Mblac2Metallo-beta-lactamase domain-containing protein 2. (279 aa)    
Predicted Functional Partners:
Olfr299
Olfactory receptor Olfr299.
      
 0.739
2510039O18Rik
Uncharacterized protein KIAA2013.
      
 0.674
Lysmd3
LysM and putative peptidoglycan-binding domain-containing protein 3; Essential for Golgi structural integrity.
 
    
 0.633
Esyt2
Extended synaptotagmin-2; Tethers the endoplasmic reticulum to the cell membrane and promotes the formation of appositions between the endoplasmic reticulum and the cell membrane. Binds glycerophospholipids in a barrel-like domain and may play a role in cellular lipid transport. Plays a role in FGF signaling via its role in the rapid internalization of FGFR1 that has been activated by FGF1 binding; this occurs most likely via the AP- 2 complex (By similarity).
      
 0.613
Rmdn3
Regulator of microtubule dynamics protein 3; Involved in cellular calcium homeostasis regulation (By similarity). May participate in differentiation and apoptosis of keratinocytes. Overexpression induces apoptosis (By similarity). Belongs to the RMDN family.
  
  
 0.602
Arl15
ADP-ribosylation factor-like protein 15; Belongs to the small GTPase superfamily. Arf family.
   
  
 0.568
Suox
Sulfite oxidase, mitochondrial.
   
  
 0.558
Lrrc39
Leucine-rich repeat-containing protein 39; Component of the sarcomeric M-band which plays a role in myocyte response to biomechanical stress. May regulate expression of other M-band proteins via an SRF-dependent pathway. Important for normal contractile function in heart.
      
 0.555
Lyrm9
LYR motif-containing protein 9; Belongs to the complex I LYR family. LYRM9 subfamily.
   
  
 0.553
Mblac1
Metallo-beta-lactamase domain-containing protein 1.
      
 0.545
Your Current Organism:
Mus musculus
NCBI taxonomy Id: 10090
Other names: LK3 transgenic mice, M. musculus, Mus sp. 129SV, house mouse, mouse, nude mice, transgenic mice
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