node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Ak8 | Catip | ENSMUSP00000073789 | ENSMUSP00000095303 | Adenylate kinase 8; Nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates. Has highest activity toward AMP, and weaker activity toward dAMP, CMP and dCMP. Also displays broad nucleoside diphosphate kinase activity. | Ciliogenesis-associated TTC17-interacting protein; Plays a role in primary ciliogenesis by modulating actin polymerization; Belongs to the CATIP family. | 0.641 |
Ak8 | Gas2l2 | ENSMUSP00000073789 | ENSMUSP00000051907 | Adenylate kinase 8; Nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates. Has highest activity toward AMP, and weaker activity toward dAMP, CMP and dCMP. Also displays broad nucleoside diphosphate kinase activity. | GAS2-like protein 2; Involved in the cross-linking of microtubules and microfilaments (By similarity). Regulates microtubule dynamics and stability by interacting with microtubule plus-end tracking proteins, such as MAPRE1, to regulate microtubule growth along actin stress fibers (By similarity). Enhances ADORA2-mediated adenylyl cyclase activation by acting as a scaffold to recruit trimeric G-protein complexes to ADORA2A. Regulates ciliary orientation and performance in cells located in the airway. | 0.590 |
Ak8 | Tekt1 | ENSMUSP00000073789 | ENSMUSP00000021155 | Adenylate kinase 8; Nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates. Has highest activity toward AMP, and weaker activity toward dAMP, CMP and dCMP. Also displays broad nucleoside diphosphate kinase activity. | Tektin-1; Structural component of ciliary and flagellar microtubules. Forms filamentous polymers in the walls of ciliary and flagellar microtubules (By similarity). | 0.447 |
Bsph2 | Gas2l2 | ENSMUSP00000104166 | ENSMUSP00000051907 | Binder of sperm protein homolog 2; Binds sperm in vitro but has no effect on sperm capacitation. Also binds gelatin and heparin, but not chondroitin sulfate B or phospholipid liposomes. | GAS2-like protein 2; Involved in the cross-linking of microtubules and microfilaments (By similarity). Regulates microtubule dynamics and stability by interacting with microtubule plus-end tracking proteins, such as MAPRE1, to regulate microtubule growth along actin stress fibers (By similarity). Enhances ADORA2-mediated adenylyl cyclase activation by acting as a scaffold to recruit trimeric G-protein complexes to ADORA2A. Regulates ciliary orientation and performance in cells located in the airway. | 0.585 |
Catip | Ak8 | ENSMUSP00000095303 | ENSMUSP00000073789 | Ciliogenesis-associated TTC17-interacting protein; Plays a role in primary ciliogenesis by modulating actin polymerization; Belongs to the CATIP family. | Adenylate kinase 8; Nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates. Has highest activity toward AMP, and weaker activity toward dAMP, CMP and dCMP. Also displays broad nucleoside diphosphate kinase activity. | 0.641 |
Catip | Gas2l2 | ENSMUSP00000095303 | ENSMUSP00000051907 | Ciliogenesis-associated TTC17-interacting protein; Plays a role in primary ciliogenesis by modulating actin polymerization; Belongs to the CATIP family. | GAS2-like protein 2; Involved in the cross-linking of microtubules and microfilaments (By similarity). Regulates microtubule dynamics and stability by interacting with microtubule plus-end tracking proteins, such as MAPRE1, to regulate microtubule growth along actin stress fibers (By similarity). Enhances ADORA2-mediated adenylyl cyclase activation by acting as a scaffold to recruit trimeric G-protein complexes to ADORA2A. Regulates ciliary orientation and performance in cells located in the airway. | 0.619 |
Cfap65 | Gas2l2 | ENSMUSP00000092440 | ENSMUSP00000051907 | Cilia- and flagella-associated protein 65; May play a role in sperm motility. Belongs to the CFAP65 family. | GAS2-like protein 2; Involved in the cross-linking of microtubules and microfilaments (By similarity). Regulates microtubule dynamics and stability by interacting with microtubule plus-end tracking proteins, such as MAPRE1, to regulate microtubule growth along actin stress fibers (By similarity). Enhances ADORA2-mediated adenylyl cyclase activation by acting as a scaffold to recruit trimeric G-protein complexes to ADORA2A. Regulates ciliary orientation and performance in cells located in the airway. | 0.633 |
Cfap65 | Vwa3a | ENSMUSP00000092440 | ENSMUSP00000033180 | Cilia- and flagella-associated protein 65; May play a role in sperm motility. Belongs to the CFAP65 family. | Von Willebrand factor A domain-containing protein 3A. | 0.615 |
Gas2l2 | Ak8 | ENSMUSP00000051907 | ENSMUSP00000073789 | GAS2-like protein 2; Involved in the cross-linking of microtubules and microfilaments (By similarity). Regulates microtubule dynamics and stability by interacting with microtubule plus-end tracking proteins, such as MAPRE1, to regulate microtubule growth along actin stress fibers (By similarity). Enhances ADORA2-mediated adenylyl cyclase activation by acting as a scaffold to recruit trimeric G-protein complexes to ADORA2A. Regulates ciliary orientation and performance in cells located in the airway. | Adenylate kinase 8; Nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates. Has highest activity toward AMP, and weaker activity toward dAMP, CMP and dCMP. Also displays broad nucleoside diphosphate kinase activity. | 0.590 |
Gas2l2 | Bsph2 | ENSMUSP00000051907 | ENSMUSP00000104166 | GAS2-like protein 2; Involved in the cross-linking of microtubules and microfilaments (By similarity). Regulates microtubule dynamics and stability by interacting with microtubule plus-end tracking proteins, such as MAPRE1, to regulate microtubule growth along actin stress fibers (By similarity). Enhances ADORA2-mediated adenylyl cyclase activation by acting as a scaffold to recruit trimeric G-protein complexes to ADORA2A. Regulates ciliary orientation and performance in cells located in the airway. | Binder of sperm protein homolog 2; Binds sperm in vitro but has no effect on sperm capacitation. Also binds gelatin and heparin, but not chondroitin sulfate B or phospholipid liposomes. | 0.585 |
Gas2l2 | Catip | ENSMUSP00000051907 | ENSMUSP00000095303 | GAS2-like protein 2; Involved in the cross-linking of microtubules and microfilaments (By similarity). Regulates microtubule dynamics and stability by interacting with microtubule plus-end tracking proteins, such as MAPRE1, to regulate microtubule growth along actin stress fibers (By similarity). Enhances ADORA2-mediated adenylyl cyclase activation by acting as a scaffold to recruit trimeric G-protein complexes to ADORA2A. Regulates ciliary orientation and performance in cells located in the airway. | Ciliogenesis-associated TTC17-interacting protein; Plays a role in primary ciliogenesis by modulating actin polymerization; Belongs to the CATIP family. | 0.619 |
Gas2l2 | Cfap65 | ENSMUSP00000051907 | ENSMUSP00000092440 | GAS2-like protein 2; Involved in the cross-linking of microtubules and microfilaments (By similarity). Regulates microtubule dynamics and stability by interacting with microtubule plus-end tracking proteins, such as MAPRE1, to regulate microtubule growth along actin stress fibers (By similarity). Enhances ADORA2-mediated adenylyl cyclase activation by acting as a scaffold to recruit trimeric G-protein complexes to ADORA2A. Regulates ciliary orientation and performance in cells located in the airway. | Cilia- and flagella-associated protein 65; May play a role in sperm motility. Belongs to the CFAP65 family. | 0.633 |
Gas2l2 | Ldlrad1 | ENSMUSP00000051907 | ENSMUSP00000092521 | GAS2-like protein 2; Involved in the cross-linking of microtubules and microfilaments (By similarity). Regulates microtubule dynamics and stability by interacting with microtubule plus-end tracking proteins, such as MAPRE1, to regulate microtubule growth along actin stress fibers (By similarity). Enhances ADORA2-mediated adenylyl cyclase activation by acting as a scaffold to recruit trimeric G-protein complexes to ADORA2A. Regulates ciliary orientation and performance in cells located in the airway. | Low density lipoprotein receptor class A domain-containing 1. | 0.535 |
Gas2l2 | Lrrc56 | ENSMUSP00000051907 | ENSMUSP00000063912 | GAS2-like protein 2; Involved in the cross-linking of microtubules and microfilaments (By similarity). Regulates microtubule dynamics and stability by interacting with microtubule plus-end tracking proteins, such as MAPRE1, to regulate microtubule growth along actin stress fibers (By similarity). Enhances ADORA2-mediated adenylyl cyclase activation by acting as a scaffold to recruit trimeric G-protein complexes to ADORA2A. Regulates ciliary orientation and performance in cells located in the airway. | Leucine-rich repeat-containing protein 56; Required for the assembly of dynein arms. | 0.507 |
Gas2l2 | Shisa3 | ENSMUSP00000051907 | ENSMUSP00000084494 | GAS2-like protein 2; Involved in the cross-linking of microtubules and microfilaments (By similarity). Regulates microtubule dynamics and stability by interacting with microtubule plus-end tracking proteins, such as MAPRE1, to regulate microtubule growth along actin stress fibers (By similarity). Enhances ADORA2-mediated adenylyl cyclase activation by acting as a scaffold to recruit trimeric G-protein complexes to ADORA2A. Regulates ciliary orientation and performance in cells located in the airway. | Protein shisa-3 homolog; Plays an essential role in the maturation of presomitic mesoderm cells by individual attenuation of both FGF and WNT signaling. Belongs to the shisa family. | 0.532 |
Gas2l2 | Tekt1 | ENSMUSP00000051907 | ENSMUSP00000021155 | GAS2-like protein 2; Involved in the cross-linking of microtubules and microfilaments (By similarity). Regulates microtubule dynamics and stability by interacting with microtubule plus-end tracking proteins, such as MAPRE1, to regulate microtubule growth along actin stress fibers (By similarity). Enhances ADORA2-mediated adenylyl cyclase activation by acting as a scaffold to recruit trimeric G-protein complexes to ADORA2A. Regulates ciliary orientation and performance in cells located in the airway. | Tektin-1; Structural component of ciliary and flagellar microtubules. Forms filamentous polymers in the walls of ciliary and flagellar microtubules (By similarity). | 0.750 |
Gas2l2 | Vwa3a | ENSMUSP00000051907 | ENSMUSP00000033180 | GAS2-like protein 2; Involved in the cross-linking of microtubules and microfilaments (By similarity). Regulates microtubule dynamics and stability by interacting with microtubule plus-end tracking proteins, such as MAPRE1, to regulate microtubule growth along actin stress fibers (By similarity). Enhances ADORA2-mediated adenylyl cyclase activation by acting as a scaffold to recruit trimeric G-protein complexes to ADORA2A. Regulates ciliary orientation and performance in cells located in the airway. | Von Willebrand factor A domain-containing protein 3A. | 0.607 |
Gas2l2 | Vwde | ENSMUSP00000051907 | ENSMUSP00000058110 | GAS2-like protein 2; Involved in the cross-linking of microtubules and microfilaments (By similarity). Regulates microtubule dynamics and stability by interacting with microtubule plus-end tracking proteins, such as MAPRE1, to regulate microtubule growth along actin stress fibers (By similarity). Enhances ADORA2-mediated adenylyl cyclase activation by acting as a scaffold to recruit trimeric G-protein complexes to ADORA2A. Regulates ciliary orientation and performance in cells located in the airway. | Von Willebrand factor D and EGF domain-containing protein. | 0.517 |
Ldlrad1 | Gas2l2 | ENSMUSP00000092521 | ENSMUSP00000051907 | Low density lipoprotein receptor class A domain-containing 1. | GAS2-like protein 2; Involved in the cross-linking of microtubules and microfilaments (By similarity). Regulates microtubule dynamics and stability by interacting with microtubule plus-end tracking proteins, such as MAPRE1, to regulate microtubule growth along actin stress fibers (By similarity). Enhances ADORA2-mediated adenylyl cyclase activation by acting as a scaffold to recruit trimeric G-protein complexes to ADORA2A. Regulates ciliary orientation and performance in cells located in the airway. | 0.535 |
Lrrc56 | Gas2l2 | ENSMUSP00000063912 | ENSMUSP00000051907 | Leucine-rich repeat-containing protein 56; Required for the assembly of dynein arms. | GAS2-like protein 2; Involved in the cross-linking of microtubules and microfilaments (By similarity). Regulates microtubule dynamics and stability by interacting with microtubule plus-end tracking proteins, such as MAPRE1, to regulate microtubule growth along actin stress fibers (By similarity). Enhances ADORA2-mediated adenylyl cyclase activation by acting as a scaffold to recruit trimeric G-protein complexes to ADORA2A. Regulates ciliary orientation and performance in cells located in the airway. | 0.507 |