node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Arhgap6 | Tmem215 | ENSMUSP00000033721 | ENSMUSP00000052129 | Rho GTPase-activating protein 6; GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state. Could regulate the interactions of signaling molecules with the actin cytoskeleton. Promotes continuous elongation of cytoplasmic processes during cell motility and simultaneous retraction of the cell body changing the cell morphology (By similarity). | Transmembrane protein 215. | 0.424 |
Arhgef16 | Tmem215 | ENSMUSP00000030898 | ENSMUSP00000052129 | Rho guanine nucleotide exchange factor 16; Guanyl-nucleotide exchange factor of the RHOG GTPase stimulating the exchange of RHOG-associated GDP for GTP. May play a role in chemotactic cell migration by mediating the activation of RAC1 by EPHA2. May also activate CDC42 (By similarity). | Transmembrane protein 215. | 0.484 |
Cdh18 | Tmem215 | ENSMUSP00000130851 | ENSMUSP00000052129 | Cadherin 18; Cadherins are calcium-dependent cell adhesion proteins. | Transmembrane protein 215. | 0.587 |
March3 | Tanc1 | ENSMUSP00000099976 | ENSMUSP00000036003 | E3 ubiquitin-protein ligase MARCHF3; E3 ubiquitin-protein ligase which may be involved in endosomal trafficking. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfer the ubiquitin to targeted substrates. | Protein TANC1; May be a scaffold component in the postsynaptic density. | 0.410 |
March3 | Tmem215 | ENSMUSP00000099976 | ENSMUSP00000052129 | E3 ubiquitin-protein ligase MARCHF3; E3 ubiquitin-protein ligase which may be involved in endosomal trafficking. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfer the ubiquitin to targeted substrates. | Transmembrane protein 215. | 0.480 |
Mex3a | Tmem215 | ENSMUSP00000134222 | ENSMUSP00000052129 | Mex3 RNA-binding family member A. | Transmembrane protein 215. | 0.461 |
Mex3a | Zswim1 | ENSMUSP00000134222 | ENSMUSP00000017908 | Mex3 RNA-binding family member A. | Zinc finger SWIM domain-containing protein 1. | 0.446 |
Prdm8 | Tmem215 | ENSMUSP00000108583 | ENSMUSP00000052129 | PR domain zinc finger protein 8; Probable histone methyltransferase, preferentially acting on 'Lys-9' of histone H3. Histone methyltransferase activity has not been confirmed in other species. Involved in the control of steroidogenesis through transcriptional repression of steroidogenesis marker genes such as CYP17A1 and LHCGR. Forms with BHLHE22 a transcriptional repressor complex controlling genes involved in neural development and neuronal differentiation. In the retina, it is required for rod bipolar and type 2 OFF-cone bipolar cell survival. | Transmembrane protein 215. | 0.504 |
Prdm8 | Vsx1 | ENSMUSP00000108583 | ENSMUSP00000039088 | PR domain zinc finger protein 8; Probable histone methyltransferase, preferentially acting on 'Lys-9' of histone H3. Histone methyltransferase activity has not been confirmed in other species. Involved in the control of steroidogenesis through transcriptional repression of steroidogenesis marker genes such as CYP17A1 and LHCGR. Forms with BHLHE22 a transcriptional repressor complex controlling genes involved in neural development and neuronal differentiation. In the retina, it is required for rod bipolar and type 2 OFF-cone bipolar cell survival. | Visual system homeobox 1; Binds to the 37-bp core of the locus control region (LCR) of the red/green visual pigment gene cluster (By similarity). May regulate the activity of the LCR and the cone opsin genes at earlier stages of development (By similarity). Dispensable in early retinal development. | 0.566 |
Tanc1 | March3 | ENSMUSP00000036003 | ENSMUSP00000099976 | Protein TANC1; May be a scaffold component in the postsynaptic density. | E3 ubiquitin-protein ligase MARCHF3; E3 ubiquitin-protein ligase which may be involved in endosomal trafficking. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfer the ubiquitin to targeted substrates. | 0.410 |
Tanc1 | Tmem215 | ENSMUSP00000036003 | ENSMUSP00000052129 | Protein TANC1; May be a scaffold component in the postsynaptic density. | Transmembrane protein 215. | 0.491 |
Thap2 | Tmem215 | ENSMUSP00000151353 | ENSMUSP00000052129 | THAP domain-containing protein 2. | Transmembrane protein 215. | 0.449 |
Tmem215 | Arhgap6 | ENSMUSP00000052129 | ENSMUSP00000033721 | Transmembrane protein 215. | Rho GTPase-activating protein 6; GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state. Could regulate the interactions of signaling molecules with the actin cytoskeleton. Promotes continuous elongation of cytoplasmic processes during cell motility and simultaneous retraction of the cell body changing the cell morphology (By similarity). | 0.424 |
Tmem215 | Arhgef16 | ENSMUSP00000052129 | ENSMUSP00000030898 | Transmembrane protein 215. | Rho guanine nucleotide exchange factor 16; Guanyl-nucleotide exchange factor of the RHOG GTPase stimulating the exchange of RHOG-associated GDP for GTP. May play a role in chemotactic cell migration by mediating the activation of RAC1 by EPHA2. May also activate CDC42 (By similarity). | 0.484 |
Tmem215 | Cdh18 | ENSMUSP00000052129 | ENSMUSP00000130851 | Transmembrane protein 215. | Cadherin 18; Cadherins are calcium-dependent cell adhesion proteins. | 0.587 |
Tmem215 | March3 | ENSMUSP00000052129 | ENSMUSP00000099976 | Transmembrane protein 215. | E3 ubiquitin-protein ligase MARCHF3; E3 ubiquitin-protein ligase which may be involved in endosomal trafficking. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfer the ubiquitin to targeted substrates. | 0.480 |
Tmem215 | Mex3a | ENSMUSP00000052129 | ENSMUSP00000134222 | Transmembrane protein 215. | Mex3 RNA-binding family member A. | 0.461 |
Tmem215 | Prdm8 | ENSMUSP00000052129 | ENSMUSP00000108583 | Transmembrane protein 215. | PR domain zinc finger protein 8; Probable histone methyltransferase, preferentially acting on 'Lys-9' of histone H3. Histone methyltransferase activity has not been confirmed in other species. Involved in the control of steroidogenesis through transcriptional repression of steroidogenesis marker genes such as CYP17A1 and LHCGR. Forms with BHLHE22 a transcriptional repressor complex controlling genes involved in neural development and neuronal differentiation. In the retina, it is required for rod bipolar and type 2 OFF-cone bipolar cell survival. | 0.504 |
Tmem215 | Tanc1 | ENSMUSP00000052129 | ENSMUSP00000036003 | Transmembrane protein 215. | Protein TANC1; May be a scaffold component in the postsynaptic density. | 0.491 |
Tmem215 | Thap2 | ENSMUSP00000052129 | ENSMUSP00000151353 | Transmembrane protein 215. | THAP domain-containing protein 2. | 0.449 |