node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Ankrd7 | Pxt1 | ENSMUSP00000111054 | ENSMUSP00000053366 | Ankyrin repeat domain-containing protein 7. | Peroxisomal testis-specific protein 1. | 0.476 |
Gnpat | Pex13 | ENSMUSP00000034466 | ENSMUSP00000020523 | Dihydroxyacetone phosphate acyltransferase; Belongs to the GPAT/DAPAT family. | Peroxisomal membrane protein PEX13; Component of the peroxisomal translocation machinery with PEX14 and PEX17. Functions as a docking factor for the predominantly cytoplasmic PTS1 receptor (PAS10/PEX5). Involved in the import of PTS1 and PTS2 proteins (By similarity). | 0.754 |
Gnpat | Pxt1 | ENSMUSP00000034466 | ENSMUSP00000053366 | Dihydroxyacetone phosphate acyltransferase; Belongs to the GPAT/DAPAT family. | Peroxisomal testis-specific protein 1. | 0.548 |
Inca1 | Nkx1-1 | ENSMUSP00000073311 | ENSMUSP00000133620 | Protein INCA1; Binds to CDK2-bound cyclins and inhibits the kinase activity of CDK2; binding to cyclins is critical for its function as CDK inhibitor. Inhibits cell growth and proliferation and may play a role in cell cycle control. Required for ING5-mediated regulation of S-phase progression, enhancement of Fas-induced apoptosis and inhibition of cell growth. | NK1 homeobox 1. | 0.461 |
Inca1 | Pxt1 | ENSMUSP00000073311 | ENSMUSP00000053366 | Protein INCA1; Binds to CDK2-bound cyclins and inhibits the kinase activity of CDK2; binding to cyclins is critical for its function as CDK inhibitor. Inhibits cell growth and proliferation and may play a role in cell cycle control. Required for ING5-mediated regulation of S-phase progression, enhancement of Fas-induced apoptosis and inhibition of cell growth. | Peroxisomal testis-specific protein 1. | 0.441 |
Lmod2 | Pxt1 | ENSMUSP00000031694 | ENSMUSP00000053366 | Leiomodin-2; Mediates nucleation of actin filaments and thereby promotes actin polymerization (By similarity). Plays a role in the regulation of actin filament length. Required for normal sarcomere organization in the heart, and for normal heart function. | Peroxisomal testis-specific protein 1. | 0.494 |
Mpv17l2 | Pxt1 | ENSMUSP00000037929 | ENSMUSP00000053366 | Mpv17-like protein 2; Required for the assembly and stability of the mitochondrial ribosome (By similarity). Is a positive regulator of mitochondrial protein synthesis (By similarity). | Peroxisomal testis-specific protein 1. | 0.418 |
Nkx1-1 | Inca1 | ENSMUSP00000133620 | ENSMUSP00000073311 | NK1 homeobox 1. | Protein INCA1; Binds to CDK2-bound cyclins and inhibits the kinase activity of CDK2; binding to cyclins is critical for its function as CDK inhibitor. Inhibits cell growth and proliferation and may play a role in cell cycle control. Required for ING5-mediated regulation of S-phase progression, enhancement of Fas-induced apoptosis and inhibition of cell growth. | 0.461 |
Nkx1-1 | Pxt1 | ENSMUSP00000133620 | ENSMUSP00000053366 | NK1 homeobox 1. | Peroxisomal testis-specific protein 1. | 0.458 |
Pex13 | Gnpat | ENSMUSP00000020523 | ENSMUSP00000034466 | Peroxisomal membrane protein PEX13; Component of the peroxisomal translocation machinery with PEX14 and PEX17. Functions as a docking factor for the predominantly cytoplasmic PTS1 receptor (PAS10/PEX5). Involved in the import of PTS1 and PTS2 proteins (By similarity). | Dihydroxyacetone phosphate acyltransferase; Belongs to the GPAT/DAPAT family. | 0.754 |
Pex13 | Pxt1 | ENSMUSP00000020523 | ENSMUSP00000053366 | Peroxisomal membrane protein PEX13; Component of the peroxisomal translocation machinery with PEX14 and PEX17. Functions as a docking factor for the predominantly cytoplasmic PTS1 receptor (PAS10/PEX5). Involved in the import of PTS1 and PTS2 proteins (By similarity). | Peroxisomal testis-specific protein 1. | 0.578 |
Pxt1 | Ankrd7 | ENSMUSP00000053366 | ENSMUSP00000111054 | Peroxisomal testis-specific protein 1. | Ankyrin repeat domain-containing protein 7. | 0.476 |
Pxt1 | Gnpat | ENSMUSP00000053366 | ENSMUSP00000034466 | Peroxisomal testis-specific protein 1. | Dihydroxyacetone phosphate acyltransferase; Belongs to the GPAT/DAPAT family. | 0.548 |
Pxt1 | Inca1 | ENSMUSP00000053366 | ENSMUSP00000073311 | Peroxisomal testis-specific protein 1. | Protein INCA1; Binds to CDK2-bound cyclins and inhibits the kinase activity of CDK2; binding to cyclins is critical for its function as CDK inhibitor. Inhibits cell growth and proliferation and may play a role in cell cycle control. Required for ING5-mediated regulation of S-phase progression, enhancement of Fas-induced apoptosis and inhibition of cell growth. | 0.441 |
Pxt1 | Lmod2 | ENSMUSP00000053366 | ENSMUSP00000031694 | Peroxisomal testis-specific protein 1. | Leiomodin-2; Mediates nucleation of actin filaments and thereby promotes actin polymerization (By similarity). Plays a role in the regulation of actin filament length. Required for normal sarcomere organization in the heart, and for normal heart function. | 0.494 |
Pxt1 | Mpv17l2 | ENSMUSP00000053366 | ENSMUSP00000037929 | Peroxisomal testis-specific protein 1. | Mpv17-like protein 2; Required for the assembly and stability of the mitochondrial ribosome (By similarity). Is a positive regulator of mitochondrial protein synthesis (By similarity). | 0.418 |
Pxt1 | Nkx1-1 | ENSMUSP00000053366 | ENSMUSP00000133620 | Peroxisomal testis-specific protein 1. | NK1 homeobox 1. | 0.458 |
Pxt1 | Pex13 | ENSMUSP00000053366 | ENSMUSP00000020523 | Peroxisomal testis-specific protein 1. | Peroxisomal membrane protein PEX13; Component of the peroxisomal translocation machinery with PEX14 and PEX17. Functions as a docking factor for the predominantly cytoplasmic PTS1 receptor (PAS10/PEX5). Involved in the import of PTS1 and PTS2 proteins (By similarity). | 0.578 |
Pxt1 | Rtn1 | ENSMUSP00000053366 | ENSMUSP00000077594 | Peroxisomal testis-specific protein 1. | Reticulon-1; May be involved in neuroendocrine secretion or in membrane trafficking in neuroendocrine cells. | 0.468 |
Pxt1 | Tnp2 | ENSMUSP00000053366 | ENSMUSP00000053078 | Peroxisomal testis-specific protein 1. | Nuclear transition protein 2; Plays a key role in the replacement of histones to protamine in the elongating spermatids of mammals. In condensing spermatids, loaded onto the nucleosomes, where it promotes the recruitment and processing of protamines, which are responsible for histone eviction. The histone H2AB1-H2BC1/TH2B dimer is required for loading of TNP2 onto chromatin. Belongs to the nuclear transition protein 2 family. | 0.430 |