node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Fah | Gstz1 | ENSMUSP00000032865 | ENSMUSP00000053540 | Fumarylacetoacetase; Belongs to the FAH family. | Maleylacetoacetate isomerase; Probable bifunctional enzyme showing minimal glutathione- conjugating activity with ethacrynic acid and 7-chloro-4-nitrobenz-2- oxa-1, 3-diazole and maleylacetoacetate isomerase activity. Has also low glutathione peroxidase activity with t-butyl and cumene hydroperoxides. Is able to catalyze the glutathione dependent oxygenation of dichloroacetic acid to glyoxylic acid (By similarity). Belongs to the GST superfamily. Zeta family. | 0.992 |
Fah | Hgd | ENSMUSP00000032865 | ENSMUSP00000125492 | Fumarylacetoacetase; Belongs to the FAH family. | Homogentisate 1,2-dioxygenase. | 0.963 |
Gstm1 | Gstm3 | ENSMUSP00000004140 | ENSMUSP00000004136 | Glutathione S-transferase Mu 1; Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. | Glutathione S-transferase Mu 3; Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles; Belongs to the GST superfamily. Mu family. | 0.808 |
Gstm1 | Gstm5 | ENSMUSP00000004140 | ENSMUSP00000004134 | Glutathione S-transferase Mu 1; Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. | Glutathione S-transferase Mu 5; Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles; Belongs to the GST superfamily. Mu family. | 0.774 |
Gstm1 | Gstm6 | ENSMUSP00000004140 | ENSMUSP00000102296 | Glutathione S-transferase Mu 1; Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. | Glutathione S-transferase Mu 6; Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. | 0.746 |
Gstm1 | Gstp1 | ENSMUSP00000004140 | ENSMUSP00000129565 | Glutathione S-transferase Mu 1; Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. | Glutathione S-transferase P 1; Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. Can metabolize 1- chloro-2,4-dinitrobenzene. Regulates negatively CDK5 activity via p25/p35 translocation to prevent neurodegeneration (By similarity). | 0.839 |
Gstm1 | Gstt1 | ENSMUSP00000004140 | ENSMUSP00000001713 | Glutathione S-transferase Mu 1; Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. | Glutathione S-transferase theta-1; Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. Also binds steroids, bilirubin, carcinogens and numerous organic anions. Has dichloromethane dehalogenase activity. | 0.975 |
Gstm1 | Gstt2 | ENSMUSP00000004140 | ENSMUSP00000151239 | Glutathione S-transferase Mu 1; Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. | Glutathione S-transferase theta-2; Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. | 0.877 |
Gstm1 | Gstz1 | ENSMUSP00000004140 | ENSMUSP00000053540 | Glutathione S-transferase Mu 1; Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. | Maleylacetoacetate isomerase; Probable bifunctional enzyme showing minimal glutathione- conjugating activity with ethacrynic acid and 7-chloro-4-nitrobenz-2- oxa-1, 3-diazole and maleylacetoacetate isomerase activity. Has also low glutathione peroxidase activity with t-butyl and cumene hydroperoxides. Is able to catalyze the glutathione dependent oxygenation of dichloroacetic acid to glyoxylic acid (By similarity). Belongs to the GST superfamily. Zeta family. | 0.847 |
Gstm1 | Hpgds | ENSMUSP00000004140 | ENSMUSP00000031982 | Glutathione S-transferase Mu 1; Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. | Hematopoietic prostaglandin D synthase; Bifunctional enzyme which catalyzes both the conversion of PGH2 to PGD2, a prostaglandin involved in smooth muscle contraction/relaxation and a potent inhibitor of platelet aggregation, and the conjugation of glutathione with a wide range of aryl halides and organic isothiocyanates. Also exhibits low glutathione-peroxidase activity. | 0.769 |
Gstm3 | Gstm1 | ENSMUSP00000004136 | ENSMUSP00000004140 | Glutathione S-transferase Mu 3; Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles; Belongs to the GST superfamily. Mu family. | Glutathione S-transferase Mu 1; Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. | 0.808 |
Gstm3 | Gstm5 | ENSMUSP00000004136 | ENSMUSP00000004134 | Glutathione S-transferase Mu 3; Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles; Belongs to the GST superfamily. Mu family. | Glutathione S-transferase Mu 5; Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles; Belongs to the GST superfamily. Mu family. | 0.763 |
Gstm3 | Gstm6 | ENSMUSP00000004136 | ENSMUSP00000102296 | Glutathione S-transferase Mu 3; Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles; Belongs to the GST superfamily. Mu family. | Glutathione S-transferase Mu 6; Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. | 0.796 |
Gstm3 | Gstp1 | ENSMUSP00000004136 | ENSMUSP00000129565 | Glutathione S-transferase Mu 3; Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles; Belongs to the GST superfamily. Mu family. | Glutathione S-transferase P 1; Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. Can metabolize 1- chloro-2,4-dinitrobenzene. Regulates negatively CDK5 activity via p25/p35 translocation to prevent neurodegeneration (By similarity). | 0.750 |
Gstm3 | Gstt1 | ENSMUSP00000004136 | ENSMUSP00000001713 | Glutathione S-transferase Mu 3; Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles; Belongs to the GST superfamily. Mu family. | Glutathione S-transferase theta-1; Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. Also binds steroids, bilirubin, carcinogens and numerous organic anions. Has dichloromethane dehalogenase activity. | 0.895 |
Gstm3 | Gstt2 | ENSMUSP00000004136 | ENSMUSP00000151239 | Glutathione S-transferase Mu 3; Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles; Belongs to the GST superfamily. Mu family. | Glutathione S-transferase theta-2; Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. | 0.844 |
Gstm3 | Gstz1 | ENSMUSP00000004136 | ENSMUSP00000053540 | Glutathione S-transferase Mu 3; Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles; Belongs to the GST superfamily. Mu family. | Maleylacetoacetate isomerase; Probable bifunctional enzyme showing minimal glutathione- conjugating activity with ethacrynic acid and 7-chloro-4-nitrobenz-2- oxa-1, 3-diazole and maleylacetoacetate isomerase activity. Has also low glutathione peroxidase activity with t-butyl and cumene hydroperoxides. Is able to catalyze the glutathione dependent oxygenation of dichloroacetic acid to glyoxylic acid (By similarity). Belongs to the GST superfamily. Zeta family. | 0.764 |
Gstm3 | Hpgds | ENSMUSP00000004136 | ENSMUSP00000031982 | Glutathione S-transferase Mu 3; Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles; Belongs to the GST superfamily. Mu family. | Hematopoietic prostaglandin D synthase; Bifunctional enzyme which catalyzes both the conversion of PGH2 to PGD2, a prostaglandin involved in smooth muscle contraction/relaxation and a potent inhibitor of platelet aggregation, and the conjugation of glutathione with a wide range of aryl halides and organic isothiocyanates. Also exhibits low glutathione-peroxidase activity. | 0.754 |
Gstm5 | Gstm1 | ENSMUSP00000004134 | ENSMUSP00000004140 | Glutathione S-transferase Mu 5; Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles; Belongs to the GST superfamily. Mu family. | Glutathione S-transferase Mu 1; Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. | 0.774 |
Gstm5 | Gstm3 | ENSMUSP00000004134 | ENSMUSP00000004136 | Glutathione S-transferase Mu 5; Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles; Belongs to the GST superfamily. Mu family. | Glutathione S-transferase Mu 3; Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles; Belongs to the GST superfamily. Mu family. | 0.763 |