node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Cxcl14 | Gpr85 | ENSMUSP00000021970 | ENSMUSP00000053837 | C-X-C motif chemokine 14; Chemotactic for CESS B-cells and THP-1 monocytes, but not T- cells. | Probable G-protein coupled receptor 85; Orphan receptor; Belongs to the G-protein coupled receptor 1 family. | 0.703 |
Gnao1 | Gpr85 | ENSMUSP00000148550 | ENSMUSP00000053837 | Guanine nucleotide-binding protein G(o) subunit alpha; Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. Stimulated by RGS14. The G(o) protein function is not clear. | Probable G-protein coupled receptor 85; Orphan receptor; Belongs to the G-protein coupled receptor 1 family. | 0.501 |
Gnao1 | Tac1 | ENSMUSP00000148550 | ENSMUSP00000139347 | Guanine nucleotide-binding protein G(o) subunit alpha; Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. Stimulated by RGS14. The G(o) protein function is not clear. | C-terminal-flanking peptide; Tachykinins are active peptides which excite neurons, evoke behavioral responses, are potent vasodilators and secretagogues, and contract (directly or indirectly) many smooth muscles; Belongs to the tachykinin family. | 0.443 |
Gpr176 | Gpr85 | ENSMUSP00000037586 | ENSMUSP00000053837 | G-protein coupled receptor 176; Orphan receptor involved in normal circadian rhythm behavior. Acts through the G-protein subclass G(z)-alpha and has an agonist-independent basal activity to repress cAMP production. | Probable G-protein coupled receptor 85; Orphan receptor; Belongs to the G-protein coupled receptor 1 family. | 0.496 |
Gpr63 | Gpr85 | ENSMUSP00000039312 | ENSMUSP00000053837 | Probable G-protein coupled receptor 63; Orphan receptor. May play a role in brain function. | Probable G-protein coupled receptor 85; Orphan receptor; Belongs to the G-protein coupled receptor 1 family. | 0.439 |
Gpr85 | Cxcl14 | ENSMUSP00000053837 | ENSMUSP00000021970 | Probable G-protein coupled receptor 85; Orphan receptor; Belongs to the G-protein coupled receptor 1 family. | C-X-C motif chemokine 14; Chemotactic for CESS B-cells and THP-1 monocytes, but not T- cells. | 0.703 |
Gpr85 | Gnao1 | ENSMUSP00000053837 | ENSMUSP00000148550 | Probable G-protein coupled receptor 85; Orphan receptor; Belongs to the G-protein coupled receptor 1 family. | Guanine nucleotide-binding protein G(o) subunit alpha; Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. Stimulated by RGS14. The G(o) protein function is not clear. | 0.501 |
Gpr85 | Gpr176 | ENSMUSP00000053837 | ENSMUSP00000037586 | Probable G-protein coupled receptor 85; Orphan receptor; Belongs to the G-protein coupled receptor 1 family. | G-protein coupled receptor 176; Orphan receptor involved in normal circadian rhythm behavior. Acts through the G-protein subclass G(z)-alpha and has an agonist-independent basal activity to repress cAMP production. | 0.496 |
Gpr85 | Gpr63 | ENSMUSP00000053837 | ENSMUSP00000039312 | Probable G-protein coupled receptor 85; Orphan receptor; Belongs to the G-protein coupled receptor 1 family. | Probable G-protein coupled receptor 63; Orphan receptor. May play a role in brain function. | 0.439 |
Gpr85 | Rbbp8nl | ENSMUSP00000053837 | ENSMUSP00000047237 | Probable G-protein coupled receptor 85; Orphan receptor; Belongs to the G-protein coupled receptor 1 family. | RBBP8 N-terminal-like. | 0.509 |
Gpr85 | Rnf139 | ENSMUSP00000053837 | ENSMUSP00000046467 | Probable G-protein coupled receptor 85; Orphan receptor; Belongs to the G-protein coupled receptor 1 family. | E3 ubiquitin-protein ligase RNF139; E3-ubiquitin ligase; acts as a negative regulator of the cell proliferation through mechanisms involving G2/M arrest and cell death. Required for MHC class I ubiquitination in cells expressing the cytomegalovirus protein US2 before dislocation from the endoplasmic reticulum (ER). Affects SREBP processing by hindering the SREBP/SCAP complex translocation from the ER to the Golgi, thereby reducing SREBF2 target gene expression. Required for INSIG1 ubiquitination. May be required for EIF3 complex ubiquitination. May function as a signaling receptor. | 0.526 |
Gpr85 | Srgap2 | ENSMUSP00000053837 | ENSMUSP00000095195 | Probable G-protein coupled receptor 85; Orphan receptor; Belongs to the G-protein coupled receptor 1 family. | SLIT-ROBO Rho GTPase-activating protein 2; RAC1 GTPase activating protein (GAP) that binds and deforms membranes, and regulates actin dynamics to regulate cell migration and differentiation. Plays an important role in different aspects of neuronal morphogenesis and migration mainly during development of the cerebral cortex. This includes the biogenesis of neurites, where it is required for both axons and dendrites outgrowth, and the maturation of the dendritic spines. Also stimulates the branching of the leading process and negatively regulates neuron radial migration in the cerebral c [...] | 0.507 |
Gpr85 | Tac1 | ENSMUSP00000053837 | ENSMUSP00000139347 | Probable G-protein coupled receptor 85; Orphan receptor; Belongs to the G-protein coupled receptor 1 family. | C-terminal-flanking peptide; Tachykinins are active peptides which excite neurons, evoke behavioral responses, are potent vasodilators and secretagogues, and contract (directly or indirectly) many smooth muscles; Belongs to the tachykinin family. | 0.436 |
Gpr85 | Tm9sf4 | ENSMUSP00000053837 | ENSMUSP00000086422 | Probable G-protein coupled receptor 85; Orphan receptor; Belongs to the G-protein coupled receptor 1 family. | Transmembrane 9 superfamily member 4; Associates with proteins harboring glycine-rich transmembrane domains and ensures their efficient localization to the cell surface. Belongs to the nonaspanin (TM9SF) (TC 9.A.2) family. | 0.423 |
Gpr85 | Tmem168 | ENSMUSP00000053837 | ENSMUSP00000031554 | Probable G-protein coupled receptor 85; Orphan receptor; Belongs to the G-protein coupled receptor 1 family. | Transmembrane protein 168. | 0.443 |
Rbbp8nl | Gpr85 | ENSMUSP00000047237 | ENSMUSP00000053837 | RBBP8 N-terminal-like. | Probable G-protein coupled receptor 85; Orphan receptor; Belongs to the G-protein coupled receptor 1 family. | 0.509 |
Rbbp8nl | Tm9sf4 | ENSMUSP00000047237 | ENSMUSP00000086422 | RBBP8 N-terminal-like. | Transmembrane 9 superfamily member 4; Associates with proteins harboring glycine-rich transmembrane domains and ensures their efficient localization to the cell surface. Belongs to the nonaspanin (TM9SF) (TC 9.A.2) family. | 0.775 |
Rnf139 | Gpr85 | ENSMUSP00000046467 | ENSMUSP00000053837 | E3 ubiquitin-protein ligase RNF139; E3-ubiquitin ligase; acts as a negative regulator of the cell proliferation through mechanisms involving G2/M arrest and cell death. Required for MHC class I ubiquitination in cells expressing the cytomegalovirus protein US2 before dislocation from the endoplasmic reticulum (ER). Affects SREBP processing by hindering the SREBP/SCAP complex translocation from the ER to the Golgi, thereby reducing SREBF2 target gene expression. Required for INSIG1 ubiquitination. May be required for EIF3 complex ubiquitination. May function as a signaling receptor. | Probable G-protein coupled receptor 85; Orphan receptor; Belongs to the G-protein coupled receptor 1 family. | 0.526 |
Srgap2 | Gpr85 | ENSMUSP00000095195 | ENSMUSP00000053837 | SLIT-ROBO Rho GTPase-activating protein 2; RAC1 GTPase activating protein (GAP) that binds and deforms membranes, and regulates actin dynamics to regulate cell migration and differentiation. Plays an important role in different aspects of neuronal morphogenesis and migration mainly during development of the cerebral cortex. This includes the biogenesis of neurites, where it is required for both axons and dendrites outgrowth, and the maturation of the dendritic spines. Also stimulates the branching of the leading process and negatively regulates neuron radial migration in the cerebral c [...] | Probable G-protein coupled receptor 85; Orphan receptor; Belongs to the G-protein coupled receptor 1 family. | 0.507 |
Tac1 | Gnao1 | ENSMUSP00000139347 | ENSMUSP00000148550 | C-terminal-flanking peptide; Tachykinins are active peptides which excite neurons, evoke behavioral responses, are potent vasodilators and secretagogues, and contract (directly or indirectly) many smooth muscles; Belongs to the tachykinin family. | Guanine nucleotide-binding protein G(o) subunit alpha; Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. Stimulated by RGS14. The G(o) protein function is not clear. | 0.443 |