STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KcnrgPotassium channel regulatory protein; Inhibits potassium fluxes in cells. May regulate Kv1 family channel proteins by retaining a fraction of channels in endomembranes (By similarity). (264 aa)    
Predicted Functional Partners:
Fau
Ubiquitin-like protein FUBI; Belongs to the ubiquitin family.
   
 
 0.877
Bpifb1
BPI fold-containing family B member 1; May play a role in innate immunity in mouth, nose and lungs. Binds bacterial lipopolysaccharide (LPS) and modulates the cellular responses to LPS. May be involved in formation of the left-right axis in the node of the developing embryo.
   
  
 0.697
Btbd10
BTB/POZ domain-containing protein 10; Plays a major role as an activator of AKT family members by inhibiting PPP2CA-mediated dephosphorylation, thereby keeping AKTs activated. Plays a role in preventing motor neuronal death and in accelerating the growth of pancreatic beta cells.
      
 0.647
Rps28
40S ribosomal protein S28; Belongs to the eukaryotic ribosomal protein eS28 family.
   
 
 0.625
Rpl34
60S ribosomal protein L34; Component of the large ribosomal subunit.
  
 
 0.622
Rpl37a
60S ribosomal protein L37a; Belongs to the eukaryotic ribosomal protein eL43 family.
   
 
 0.617
Rpl31
60S ribosomal protein L31; Belongs to the eukaryotic ribosomal protein eL31 family.
   
 
 0.617
Rpl23a
60S ribosomal protein L23a; Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. Binds a specific region on the 26S rRNA (By similarity). May promote p53/TP53 degradation possibly through the stimulation of MDM2-mediated TP53 polyubiquitination (By similarity); Belongs to the universal ribosomal protein uL23 family.
   
 
 0.615
Rpl23
60S ribosomal protein L23.
   
 
 0.613
Rpl38
60S ribosomal protein L38; Belongs to the eukaryotic ribosomal protein eL38 family.
   
 
 0.613
Your Current Organism:
Mus musculus
NCBI taxonomy Id: 10090
Other names: LK3 transgenic mice, M. musculus, Mus sp. 129SV, house mouse, mouse, nude mice, transgenic mice
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