node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Akap6 | Bmpr2 | ENSMUSP00000093406 | ENSMUSP00000084701 | A kinase (PRKA) anchor protein 6. | Bone morphogenetic protein receptor type-2; On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Binds to BMP7, BMP2 and, less efficiently, BMP4. Binding is weak but enhanced by the presence of type I receptors for BMPs. Mediates induction of adipogenesis by GDF6. | 0.431 |
Akap6 | Grip2 | ENSMUSP00000093406 | ENSMUSP00000124709 | A kinase (PRKA) anchor protein 6. | Glutamate receptor-interacting protein 2. | 0.606 |
Akap6 | Gtf2f1 | ENSMUSP00000093406 | ENSMUSP00000002733 | A kinase (PRKA) anchor protein 6. | General transcription factor IIF subunit 1; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation (By similarity); Belongs to the TFIIF alpha subunit family. | 0.601 |
Akap6 | Rusc2 | ENSMUSP00000093406 | ENSMUSP00000095710 | A kinase (PRKA) anchor protein 6. | Iporin. | 0.634 |
Akap6 | Zfp668 | ENSMUSP00000093406 | ENSMUSP00000056105 | A kinase (PRKA) anchor protein 6. | Zinc finger protein 668; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family. | 0.625 |
Bmpr2 | Akap6 | ENSMUSP00000084701 | ENSMUSP00000093406 | Bone morphogenetic protein receptor type-2; On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Binds to BMP7, BMP2 and, less efficiently, BMP4. Binding is weak but enhanced by the presence of type I receptors for BMPs. Mediates induction of adipogenesis by GDF6. | A kinase (PRKA) anchor protein 6. | 0.431 |
Bmpr2 | Grip2 | ENSMUSP00000084701 | ENSMUSP00000124709 | Bone morphogenetic protein receptor type-2; On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Binds to BMP7, BMP2 and, less efficiently, BMP4. Binding is weak but enhanced by the presence of type I receptors for BMPs. Mediates induction of adipogenesis by GDF6. | Glutamate receptor-interacting protein 2. | 0.435 |
Bmpr2 | Gtf2f1 | ENSMUSP00000084701 | ENSMUSP00000002733 | Bone morphogenetic protein receptor type-2; On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Binds to BMP7, BMP2 and, less efficiently, BMP4. Binding is weak but enhanced by the presence of type I receptors for BMPs. Mediates induction of adipogenesis by GDF6. | General transcription factor IIF subunit 1; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation (By similarity); Belongs to the TFIIF alpha subunit family. | 0.499 |
Bmpr2 | Zfp668 | ENSMUSP00000084701 | ENSMUSP00000056105 | Bone morphogenetic protein receptor type-2; On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Binds to BMP7, BMP2 and, less efficiently, BMP4. Binding is weak but enhanced by the presence of type I receptors for BMPs. Mediates induction of adipogenesis by GDF6. | Zinc finger protein 668; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family. | 0.518 |
Galnt7 | Sec23ip | ENSMUSP00000034021 | ENSMUSP00000035610 | N-acetylgalactosaminyltransferase 7; Glycopeptide transferase involved in O-linked oligosaccharide biosynthesis, which catalyzes the transfer of an N-acetyl-D- galactosamine residue to an already glycosylated peptide. In contrast to other proteins of the family, it does not act as a peptide transferase that transfers GalNAc onto serine or threonine residue on the protein receptor, but instead requires the prior addition of a GalNAc on a peptide before adding additional GalNAc moieties. Some peptide transferase activity is however not excluded, considering that its appropriate peptide s [...] | SEC23-interacting protein; Plays a role in the organization of endoplasmic reticulum exit sites. Specifically binds to phosphatidylinositol 3-phosphate (PI(3)P), phosphatidylinositol 4-phosphate (PI(4)P) and phosphatidylinositol 5-phosphate (PI(5)P). | 0.573 |
Galnt7 | Zfp668 | ENSMUSP00000034021 | ENSMUSP00000056105 | N-acetylgalactosaminyltransferase 7; Glycopeptide transferase involved in O-linked oligosaccharide biosynthesis, which catalyzes the transfer of an N-acetyl-D- galactosamine residue to an already glycosylated peptide. In contrast to other proteins of the family, it does not act as a peptide transferase that transfers GalNAc onto serine or threonine residue on the protein receptor, but instead requires the prior addition of a GalNAc on a peptide before adding additional GalNAc moieties. Some peptide transferase activity is however not excluded, considering that its appropriate peptide s [...] | Zinc finger protein 668; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family. | 0.590 |
Grip2 | Akap6 | ENSMUSP00000124709 | ENSMUSP00000093406 | Glutamate receptor-interacting protein 2. | A kinase (PRKA) anchor protein 6. | 0.606 |
Grip2 | Bmpr2 | ENSMUSP00000124709 | ENSMUSP00000084701 | Glutamate receptor-interacting protein 2. | Bone morphogenetic protein receptor type-2; On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Binds to BMP7, BMP2 and, less efficiently, BMP4. Binding is weak but enhanced by the presence of type I receptors for BMPs. Mediates induction of adipogenesis by GDF6. | 0.435 |
Grip2 | Gtf2f1 | ENSMUSP00000124709 | ENSMUSP00000002733 | Glutamate receptor-interacting protein 2. | General transcription factor IIF subunit 1; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation (By similarity); Belongs to the TFIIF alpha subunit family. | 0.555 |
Grip2 | Rusc2 | ENSMUSP00000124709 | ENSMUSP00000095710 | Glutamate receptor-interacting protein 2. | Iporin. | 0.600 |
Grip2 | Zfp668 | ENSMUSP00000124709 | ENSMUSP00000056105 | Glutamate receptor-interacting protein 2. | Zinc finger protein 668; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family. | 0.651 |
Gtf2f1 | Akap6 | ENSMUSP00000002733 | ENSMUSP00000093406 | General transcription factor IIF subunit 1; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation (By similarity); Belongs to the TFIIF alpha subunit family. | A kinase (PRKA) anchor protein 6. | 0.601 |
Gtf2f1 | Bmpr2 | ENSMUSP00000002733 | ENSMUSP00000084701 | General transcription factor IIF subunit 1; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation (By similarity); Belongs to the TFIIF alpha subunit family. | Bone morphogenetic protein receptor type-2; On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Binds to BMP7, BMP2 and, less efficiently, BMP4. Binding is weak but enhanced by the presence of type I receptors for BMPs. Mediates induction of adipogenesis by GDF6. | 0.499 |
Gtf2f1 | Grip2 | ENSMUSP00000002733 | ENSMUSP00000124709 | General transcription factor IIF subunit 1; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation (By similarity); Belongs to the TFIIF alpha subunit family. | Glutamate receptor-interacting protein 2. | 0.555 |
Gtf2f1 | Rusc2 | ENSMUSP00000002733 | ENSMUSP00000095710 | General transcription factor IIF subunit 1; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation (By similarity); Belongs to the TFIIF alpha subunit family. | Iporin. | 0.655 |