| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Fau | Npsr1 | ENSMUSP00000136358 | ENSMUSP00000056432 | Ubiquitin-like protein FUBI; Belongs to the ubiquitin family. | Neuropeptide S receptor; G-protein coupled receptor for neuropeptide S (NPS). Promotes mobilization of intracellular Ca(2+) stores. Inhibits cell growth in response to NPS binding. Involved in pathogenesis of asthma and other IgE-mediated diseases. | 0.997 |
| Fau | Rpl15 | ENSMUSP00000136358 | ENSMUSP00000079163 | Ubiquitin-like protein FUBI; Belongs to the ubiquitin family. | 60S ribosomal protein L15; Belongs to the eukaryotic ribosomal protein eL15 family. | 0.999 |
| Fau | Rpl19 | ENSMUSP00000136358 | ENSMUSP00000017548 | Ubiquitin-like protein FUBI; Belongs to the ubiquitin family. | 60S ribosomal protein L19. | 0.999 |
| Fau | Rpl21 | ENSMUSP00000136358 | ENSMUSP00000041652 | Ubiquitin-like protein FUBI; Belongs to the ubiquitin family. | 60S ribosomal protein L21; Component of the large ribosomal subunit. | 0.999 |
| Fau | Rpl32 | ENSMUSP00000136358 | ENSMUSP00000145350 | Ubiquitin-like protein FUBI; Belongs to the ubiquitin family. | 60S ribosomal protein L32; Belongs to the eukaryotic ribosomal protein eL32 family. | 0.999 |
| Fau | Rpl5 | ENSMUSP00000136358 | ENSMUSP00000080854 | Ubiquitin-like protein FUBI; Belongs to the ubiquitin family. | 60S ribosomal protein L5; Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules. The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain. The nascent polypeptides leave the ribosome through [...] | 0.999 |
| Fau | Rps3 | ENSMUSP00000136358 | ENSMUSP00000032998 | Ubiquitin-like protein FUBI; Belongs to the ubiquitin family. | 40S ribosomal protein S3; Involved in translation as a component of the 40S small ribosomal subunit (By similarity). Has endonuclease activity and plays a role in repair of damaged DNA. Cleaves phosphodiester bonds of DNAs containing altered bases with broad specificity and cleaves supercoiled DNA more efficiently than relaxed DNA (By similarity). Displays high binding affinity for 7,8-dihydro-8- oxoguanine (8-oxoG), a common DNA lesion caused by reactive oxygen species (ROS) (By similarity). Has also been shown to bind with similar affinity to intact and damaged DNA (By similarity). S [...] | 0.999 |
| Fau | Rps3a1 | ENSMUSP00000136358 | ENSMUSP00000029722 | Ubiquitin-like protein FUBI; Belongs to the ubiquitin family. | 40S ribosomal protein S3a; May play a role during erythropoiesis through regulation of transcription factor DDIT3. | 0.999 |
| Fau | Rps6 | ENSMUSP00000136358 | ENSMUSP00000099878 | Ubiquitin-like protein FUBI; Belongs to the ubiquitin family. | 40S ribosomal protein S6; May play an important role in controlling cell growth and proliferation through the selective translation of particular classes of mRNA. | 0.999 |
| Nps | Npsr1 | ENSMUSP00000095597 | ENSMUSP00000056432 | Neuropeptide S; May play an important anorexigenic role. Modulates arousal and anxiety as well as increases locomotor activity. Binds to its receptor NPSR1 with nanomolar affinity to increase intracellular calcium concentrations. | Neuropeptide S receptor; G-protein coupled receptor for neuropeptide S (NPS). Promotes mobilization of intracellular Ca(2+) stores. Inhibits cell growth in response to NPS binding. Involved in pathogenesis of asthma and other IgE-mediated diseases. | 0.997 |
| Npsr1 | Fau | ENSMUSP00000056432 | ENSMUSP00000136358 | Neuropeptide S receptor; G-protein coupled receptor for neuropeptide S (NPS). Promotes mobilization of intracellular Ca(2+) stores. Inhibits cell growth in response to NPS binding. Involved in pathogenesis of asthma and other IgE-mediated diseases. | Ubiquitin-like protein FUBI; Belongs to the ubiquitin family. | 0.997 |
| Npsr1 | Nps | ENSMUSP00000056432 | ENSMUSP00000095597 | Neuropeptide S receptor; G-protein coupled receptor for neuropeptide S (NPS). Promotes mobilization of intracellular Ca(2+) stores. Inhibits cell growth in response to NPS binding. Involved in pathogenesis of asthma and other IgE-mediated diseases. | Neuropeptide S; May play an important anorexigenic role. Modulates arousal and anxiety as well as increases locomotor activity. Binds to its receptor NPSR1 with nanomolar affinity to increase intracellular calcium concentrations. | 0.997 |
| Npsr1 | Rpl15 | ENSMUSP00000056432 | ENSMUSP00000079163 | Neuropeptide S receptor; G-protein coupled receptor for neuropeptide S (NPS). Promotes mobilization of intracellular Ca(2+) stores. Inhibits cell growth in response to NPS binding. Involved in pathogenesis of asthma and other IgE-mediated diseases. | 60S ribosomal protein L15; Belongs to the eukaryotic ribosomal protein eL15 family. | 0.942 |
| Npsr1 | Rpl19 | ENSMUSP00000056432 | ENSMUSP00000017548 | Neuropeptide S receptor; G-protein coupled receptor for neuropeptide S (NPS). Promotes mobilization of intracellular Ca(2+) stores. Inhibits cell growth in response to NPS binding. Involved in pathogenesis of asthma and other IgE-mediated diseases. | 60S ribosomal protein L19. | 0.949 |
| Npsr1 | Rpl21 | ENSMUSP00000056432 | ENSMUSP00000041652 | Neuropeptide S receptor; G-protein coupled receptor for neuropeptide S (NPS). Promotes mobilization of intracellular Ca(2+) stores. Inhibits cell growth in response to NPS binding. Involved in pathogenesis of asthma and other IgE-mediated diseases. | 60S ribosomal protein L21; Component of the large ribosomal subunit. | 0.945 |
| Npsr1 | Rpl32 | ENSMUSP00000056432 | ENSMUSP00000145350 | Neuropeptide S receptor; G-protein coupled receptor for neuropeptide S (NPS). Promotes mobilization of intracellular Ca(2+) stores. Inhibits cell growth in response to NPS binding. Involved in pathogenesis of asthma and other IgE-mediated diseases. | 60S ribosomal protein L32; Belongs to the eukaryotic ribosomal protein eL32 family. | 0.949 |
| Npsr1 | Rpl5 | ENSMUSP00000056432 | ENSMUSP00000080854 | Neuropeptide S receptor; G-protein coupled receptor for neuropeptide S (NPS). Promotes mobilization of intracellular Ca(2+) stores. Inhibits cell growth in response to NPS binding. Involved in pathogenesis of asthma and other IgE-mediated diseases. | 60S ribosomal protein L5; Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules. The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain. The nascent polypeptides leave the ribosome through [...] | 0.954 |
| Npsr1 | Rps3 | ENSMUSP00000056432 | ENSMUSP00000032998 | Neuropeptide S receptor; G-protein coupled receptor for neuropeptide S (NPS). Promotes mobilization of intracellular Ca(2+) stores. Inhibits cell growth in response to NPS binding. Involved in pathogenesis of asthma and other IgE-mediated diseases. | 40S ribosomal protein S3; Involved in translation as a component of the 40S small ribosomal subunit (By similarity). Has endonuclease activity and plays a role in repair of damaged DNA. Cleaves phosphodiester bonds of DNAs containing altered bases with broad specificity and cleaves supercoiled DNA more efficiently than relaxed DNA (By similarity). Displays high binding affinity for 7,8-dihydro-8- oxoguanine (8-oxoG), a common DNA lesion caused by reactive oxygen species (ROS) (By similarity). Has also been shown to bind with similar affinity to intact and damaged DNA (By similarity). S [...] | 0.949 |
| Npsr1 | Rps3a1 | ENSMUSP00000056432 | ENSMUSP00000029722 | Neuropeptide S receptor; G-protein coupled receptor for neuropeptide S (NPS). Promotes mobilization of intracellular Ca(2+) stores. Inhibits cell growth in response to NPS binding. Involved in pathogenesis of asthma and other IgE-mediated diseases. | 40S ribosomal protein S3a; May play a role during erythropoiesis through regulation of transcription factor DDIT3. | 0.945 |
| Npsr1 | Rps6 | ENSMUSP00000056432 | ENSMUSP00000099878 | Neuropeptide S receptor; G-protein coupled receptor for neuropeptide S (NPS). Promotes mobilization of intracellular Ca(2+) stores. Inhibits cell growth in response to NPS binding. Involved in pathogenesis of asthma and other IgE-mediated diseases. | 40S ribosomal protein S6; May play an important role in controlling cell growth and proliferation through the selective translation of particular classes of mRNA. | 0.947 |
STRING v12.5 is now available!
