node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Fancm | Ldoc1 | ENSMUSP00000054797 | ENSMUSP00000075366 | Fanconi anemia group M protein homolog; DNA-dependent ATPase component of the Fanconi anemia (FA) core complex. Required for the normal activation of the FA pathway, leading to monoubiquitination of the FANCI-FANCD2 complex in response to DNA damage, cellular resistance to DNA cross-linking drugs, and prevention of chromosomal breakage. In complex with CENPS and CENPX, binds double-stranded DNA (dsDNA), fork-structured DNA (fsDNA) and Holliday junction substrates. Its ATP-dependent DNA branch migration activity can process branched DNA structures such as a movable replication fork. Thi [...] | Protein LDOC1; May have an important role in the development and/or progression of some cancers. | 0.679 |
Fancm | Pnma3 | ENSMUSP00000054797 | ENSMUSP00000054177 | Fanconi anemia group M protein homolog; DNA-dependent ATPase component of the Fanconi anemia (FA) core complex. Required for the normal activation of the FA pathway, leading to monoubiquitination of the FANCI-FANCD2 complex in response to DNA damage, cellular resistance to DNA cross-linking drugs, and prevention of chromosomal breakage. In complex with CENPS and CENPX, binds double-stranded DNA (dsDNA), fork-structured DNA (fsDNA) and Holliday junction substrates. Its ATP-dependent DNA branch migration activity can process branched DNA structures such as a movable replication fork. Thi [...] | Paraneoplastic antigen Ma3 homolog; Belongs to the PNMA family. | 0.679 |
Fancm | Pnma5 | ENSMUSP00000054797 | ENSMUSP00000063061 | Fanconi anemia group M protein homolog; DNA-dependent ATPase component of the Fanconi anemia (FA) core complex. Required for the normal activation of the FA pathway, leading to monoubiquitination of the FANCI-FANCD2 complex in response to DNA damage, cellular resistance to DNA cross-linking drugs, and prevention of chromosomal breakage. In complex with CENPS and CENPX, binds double-stranded DNA (dsDNA), fork-structured DNA (fsDNA) and Holliday junction substrates. Its ATP-dependent DNA branch migration activity can process branched DNA structures such as a movable replication fork. Thi [...] | Paraneoplastic antigen-like protein 5. | 0.679 |
Fancm | Pnmal1 | ENSMUSP00000054797 | ENSMUSP00000040929 | Fanconi anemia group M protein homolog; DNA-dependent ATPase component of the Fanconi anemia (FA) core complex. Required for the normal activation of the FA pathway, leading to monoubiquitination of the FANCI-FANCD2 complex in response to DNA damage, cellular resistance to DNA cross-linking drugs, and prevention of chromosomal breakage. In complex with CENPS and CENPX, binds double-stranded DNA (dsDNA), fork-structured DNA (fsDNA) and Holliday junction substrates. Its ATP-dependent DNA branch migration activity can process branched DNA structures such as a movable replication fork. Thi [...] | Paraneoplastic antigen-like protein 8A; Belongs to the PNMA family. | 0.680 |
Fancm | Rtl3 | ENSMUSP00000054797 | ENSMUSP00000060157 | Fanconi anemia group M protein homolog; DNA-dependent ATPase component of the Fanconi anemia (FA) core complex. Required for the normal activation of the FA pathway, leading to monoubiquitination of the FANCI-FANCD2 complex in response to DNA damage, cellular resistance to DNA cross-linking drugs, and prevention of chromosomal breakage. In complex with CENPS and CENPX, binds double-stranded DNA (dsDNA), fork-structured DNA (fsDNA) and Holliday junction substrates. Its ATP-dependent DNA branch migration activity can process branched DNA structures such as a movable replication fork. Thi [...] | Retrotransposon Gag-like protein 3; May function as a transcriptional regulator (Probable). Plays a role in postnatal myogenesis, may be involved in the regulation of satellite cells self-renewal. | 0.679 |
Fancm | Rtl6 | ENSMUSP00000054797 | ENSMUSP00000069947 | Fanconi anemia group M protein homolog; DNA-dependent ATPase component of the Fanconi anemia (FA) core complex. Required for the normal activation of the FA pathway, leading to monoubiquitination of the FANCI-FANCD2 complex in response to DNA damage, cellular resistance to DNA cross-linking drugs, and prevention of chromosomal breakage. In complex with CENPS and CENPX, binds double-stranded DNA (dsDNA), fork-structured DNA (fsDNA) and Holliday junction substrates. Its ATP-dependent DNA branch migration activity can process branched DNA structures such as a movable replication fork. Thi [...] | Retrotransposon Gag-like protein 6. | 0.679 |
Fancm | Rtl8a | ENSMUSP00000054797 | ENSMUSP00000086158 | Fanconi anemia group M protein homolog; DNA-dependent ATPase component of the Fanconi anemia (FA) core complex. Required for the normal activation of the FA pathway, leading to monoubiquitination of the FANCI-FANCD2 complex in response to DNA damage, cellular resistance to DNA cross-linking drugs, and prevention of chromosomal breakage. In complex with CENPS and CENPX, binds double-stranded DNA (dsDNA), fork-structured DNA (fsDNA) and Holliday junction substrates. Its ATP-dependent DNA branch migration activity can process branched DNA structures such as a movable replication fork. Thi [...] | Retrotransposon Gag like 8A. | 0.679 |
Fancm | Rtl9 | ENSMUSP00000054797 | ENSMUSP00000128287 | Fanconi anemia group M protein homolog; DNA-dependent ATPase component of the Fanconi anemia (FA) core complex. Required for the normal activation of the FA pathway, leading to monoubiquitination of the FANCI-FANCD2 complex in response to DNA damage, cellular resistance to DNA cross-linking drugs, and prevention of chromosomal breakage. In complex with CENPS and CENPX, binds double-stranded DNA (dsDNA), fork-structured DNA (fsDNA) and Holliday junction substrates. Its ATP-dependent DNA branch migration activity can process branched DNA structures such as a movable replication fork. Thi [...] | Retrotransposon Gag-like protein 9. | 0.679 |
Gm17657 | Rtl3 | ENSMUSP00000157004 | ENSMUSP00000060157 | Predicted gene, 17657. | Retrotransposon Gag-like protein 3; May function as a transcriptional regulator (Probable). Plays a role in postnatal myogenesis, may be involved in the regulation of satellite cells self-renewal. | 0.449 |
Ldoc1 | Fancm | ENSMUSP00000075366 | ENSMUSP00000054797 | Protein LDOC1; May have an important role in the development and/or progression of some cancers. | Fanconi anemia group M protein homolog; DNA-dependent ATPase component of the Fanconi anemia (FA) core complex. Required for the normal activation of the FA pathway, leading to monoubiquitination of the FANCI-FANCD2 complex in response to DNA damage, cellular resistance to DNA cross-linking drugs, and prevention of chromosomal breakage. In complex with CENPS and CENPX, binds double-stranded DNA (dsDNA), fork-structured DNA (fsDNA) and Holliday junction substrates. Its ATP-dependent DNA branch migration activity can process branched DNA structures such as a movable replication fork. Thi [...] | 0.679 |
Ldoc1 | Pnma5 | ENSMUSP00000075366 | ENSMUSP00000063061 | Protein LDOC1; May have an important role in the development and/or progression of some cancers. | Paraneoplastic antigen-like protein 5. | 0.489 |
Ldoc1 | Rtl3 | ENSMUSP00000075366 | ENSMUSP00000060157 | Protein LDOC1; May have an important role in the development and/or progression of some cancers. | Retrotransposon Gag-like protein 3; May function as a transcriptional regulator (Probable). Plays a role in postnatal myogenesis, may be involved in the regulation of satellite cells self-renewal. | 0.537 |
Ldoc1 | Rtl9 | ENSMUSP00000075366 | ENSMUSP00000128287 | Protein LDOC1; May have an important role in the development and/or progression of some cancers. | Retrotransposon Gag-like protein 9. | 0.677 |
Pnma3 | Fancm | ENSMUSP00000054177 | ENSMUSP00000054797 | Paraneoplastic antigen Ma3 homolog; Belongs to the PNMA family. | Fanconi anemia group M protein homolog; DNA-dependent ATPase component of the Fanconi anemia (FA) core complex. Required for the normal activation of the FA pathway, leading to monoubiquitination of the FANCI-FANCD2 complex in response to DNA damage, cellular resistance to DNA cross-linking drugs, and prevention of chromosomal breakage. In complex with CENPS and CENPX, binds double-stranded DNA (dsDNA), fork-structured DNA (fsDNA) and Holliday junction substrates. Its ATP-dependent DNA branch migration activity can process branched DNA structures such as a movable replication fork. Thi [...] | 0.679 |
Pnma3 | Pnmal1 | ENSMUSP00000054177 | ENSMUSP00000040929 | Paraneoplastic antigen Ma3 homolog; Belongs to the PNMA family. | Paraneoplastic antigen-like protein 8A; Belongs to the PNMA family. | 0.442 |
Pnma3 | Rtl3 | ENSMUSP00000054177 | ENSMUSP00000060157 | Paraneoplastic antigen Ma3 homolog; Belongs to the PNMA family. | Retrotransposon Gag-like protein 3; May function as a transcriptional regulator (Probable). Plays a role in postnatal myogenesis, may be involved in the regulation of satellite cells self-renewal. | 0.548 |
Pnma5 | Fancm | ENSMUSP00000063061 | ENSMUSP00000054797 | Paraneoplastic antigen-like protein 5. | Fanconi anemia group M protein homolog; DNA-dependent ATPase component of the Fanconi anemia (FA) core complex. Required for the normal activation of the FA pathway, leading to monoubiquitination of the FANCI-FANCD2 complex in response to DNA damage, cellular resistance to DNA cross-linking drugs, and prevention of chromosomal breakage. In complex with CENPS and CENPX, binds double-stranded DNA (dsDNA), fork-structured DNA (fsDNA) and Holliday junction substrates. Its ATP-dependent DNA branch migration activity can process branched DNA structures such as a movable replication fork. Thi [...] | 0.679 |
Pnma5 | Ldoc1 | ENSMUSP00000063061 | ENSMUSP00000075366 | Paraneoplastic antigen-like protein 5. | Protein LDOC1; May have an important role in the development and/or progression of some cancers. | 0.489 |
Pnma5 | Rtl3 | ENSMUSP00000063061 | ENSMUSP00000060157 | Paraneoplastic antigen-like protein 5. | Retrotransposon Gag-like protein 3; May function as a transcriptional regulator (Probable). Plays a role in postnatal myogenesis, may be involved in the regulation of satellite cells self-renewal. | 0.592 |
Pnma5 | Rtl6 | ENSMUSP00000063061 | ENSMUSP00000069947 | Paraneoplastic antigen-like protein 5. | Retrotransposon Gag-like protein 6. | 0.471 |