node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Clns1a | Ints4 | ENSMUSP00000026506 | ENSMUSP00000026126 | Methylosome subunit pICln; Involved in both the assembly of spliceosomal snRNPs and the methylation of Sm proteins (By similarity). Chaperone that regulates the assembly of spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Thereby, plays an important role in the splicing of cellular pre-mRNAs. Most spliceosomal snRNPs contain a common set of Sm proteins SNRPB, SNRPD1, SNRPD2, SNRPD3, SNRPE, SNRPF and SNRPG that assemble in a heptameric protein ring on the Sm site of the small nuclear RNA to form the core snRNP. In the cyto [...] | Integrator complex subunit 4; Component of the Integrator (INT) complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3'-box-dependent processing. The Integrator complex is associated with the C-terminal domain (CTD) of RNA polymerase II largest subunit (POLR2A) and is recruited to the U1 and U2 snRNAs genes. Mediates recruitment of cytoplasmic dynein to the nuclear envelope, probably as component of the INT complex. | 0.401 |
Clns1a | Kctd14 | ENSMUSP00000026506 | ENSMUSP00000145558 | Methylosome subunit pICln; Involved in both the assembly of spliceosomal snRNPs and the methylation of Sm proteins (By similarity). Chaperone that regulates the assembly of spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Thereby, plays an important role in the splicing of cellular pre-mRNAs. Most spliceosomal snRNPs contain a common set of Sm proteins SNRPB, SNRPD1, SNRPD2, SNRPD3, SNRPE, SNRPF and SNRPG that assemble in a heptameric protein ring on the Sm site of the small nuclear RNA to form the core snRNP. In the cyto [...] | Potassium channel tetramerisation domain-containing 14. | 0.443 |
Ints4 | Clns1a | ENSMUSP00000026126 | ENSMUSP00000026506 | Integrator complex subunit 4; Component of the Integrator (INT) complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3'-box-dependent processing. The Integrator complex is associated with the C-terminal domain (CTD) of RNA polymerase II largest subunit (POLR2A) and is recruited to the U1 and U2 snRNAs genes. Mediates recruitment of cytoplasmic dynein to the nuclear envelope, probably as component of the INT complex. | Methylosome subunit pICln; Involved in both the assembly of spliceosomal snRNPs and the methylation of Sm proteins (By similarity). Chaperone that regulates the assembly of spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Thereby, plays an important role in the splicing of cellular pre-mRNAs. Most spliceosomal snRNPs contain a common set of Sm proteins SNRPB, SNRPD1, SNRPD2, SNRPD3, SNRPE, SNRPF and SNRPG that assemble in a heptameric protein ring on the Sm site of the small nuclear RNA to form the core snRNP. In the cyto [...] | 0.401 |
Ints4 | Kctd14 | ENSMUSP00000026126 | ENSMUSP00000145558 | Integrator complex subunit 4; Component of the Integrator (INT) complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3'-box-dependent processing. The Integrator complex is associated with the C-terminal domain (CTD) of RNA polymerase II largest subunit (POLR2A) and is recruited to the U1 and U2 snRNAs genes. Mediates recruitment of cytoplasmic dynein to the nuclear envelope, probably as component of the INT complex. | Potassium channel tetramerisation domain-containing 14. | 0.549 |
Kctd14 | Clns1a | ENSMUSP00000145558 | ENSMUSP00000026506 | Potassium channel tetramerisation domain-containing 14. | Methylosome subunit pICln; Involved in both the assembly of spliceosomal snRNPs and the methylation of Sm proteins (By similarity). Chaperone that regulates the assembly of spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Thereby, plays an important role in the splicing of cellular pre-mRNAs. Most spliceosomal snRNPs contain a common set of Sm proteins SNRPB, SNRPD1, SNRPD2, SNRPD3, SNRPE, SNRPF and SNRPG that assemble in a heptameric protein ring on the Sm site of the small nuclear RNA to form the core snRNP. In the cyto [...] | 0.443 |
Kctd14 | Ints4 | ENSMUSP00000145558 | ENSMUSP00000026126 | Potassium channel tetramerisation domain-containing 14. | Integrator complex subunit 4; Component of the Integrator (INT) complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3'-box-dependent processing. The Integrator complex is associated with the C-terminal domain (CTD) of RNA polymerase II largest subunit (POLR2A) and is recruited to the U1 and U2 snRNAs genes. Mediates recruitment of cytoplasmic dynein to the nuclear envelope, probably as component of the INT complex. | 0.549 |
Kctd14 | Kctd9 | ENSMUSP00000145558 | ENSMUSP00000114489 | Potassium channel tetramerisation domain-containing 14. | BTB/POZ domain-containing protein KCTD9; Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex, which mediates the ubiquitination of target proteins, leading to their degradation by the proteasome. | 0.456 |
Kctd14 | Slc7a15 | ENSMUSP00000145558 | ENSMUSP00000093548 | Potassium channel tetramerisation domain-containing 14. | Solute carrier family 7 (cationic amino acid transporter, y+ system), member 15. | 0.523 |
Kctd14 | Smim3 | ENSMUSP00000145558 | ENSMUSP00000039285 | Potassium channel tetramerisation domain-containing 14. | Small integral membrane protein 3. | 0.572 |
Kctd14 | Spred3 | ENSMUSP00000145558 | ENSMUSP00000046216 | Potassium channel tetramerisation domain-containing 14. | Sprouty-related, EVH1 domain-containing protein 3; Tyrosine kinase substrate that inhibits growth-factor- mediated activation of MAP kinase. | 0.455 |
Kctd14 | Tmem184a | ENSMUSP00000145558 | ENSMUSP00000035399 | Potassium channel tetramerisation domain-containing 14. | Transmembrane protein 184A; Acts as a heparin receptor in vascular cells (By similarity). May be involved in vesicle transport in exocrine cells and Sertoli cells. Belongs to the TMEM184 family. | 0.680 |
Kctd9 | Kctd14 | ENSMUSP00000114489 | ENSMUSP00000145558 | BTB/POZ domain-containing protein KCTD9; Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex, which mediates the ubiquitination of target proteins, leading to their degradation by the proteasome. | Potassium channel tetramerisation domain-containing 14. | 0.456 |
Slc7a15 | Kctd14 | ENSMUSP00000093548 | ENSMUSP00000145558 | Solute carrier family 7 (cationic amino acid transporter, y+ system), member 15. | Potassium channel tetramerisation domain-containing 14. | 0.523 |
Smim3 | Kctd14 | ENSMUSP00000039285 | ENSMUSP00000145558 | Small integral membrane protein 3. | Potassium channel tetramerisation domain-containing 14. | 0.572 |
Smim3 | Spred3 | ENSMUSP00000039285 | ENSMUSP00000046216 | Small integral membrane protein 3. | Sprouty-related, EVH1 domain-containing protein 3; Tyrosine kinase substrate that inhibits growth-factor- mediated activation of MAP kinase. | 0.562 |
Spred3 | Kctd14 | ENSMUSP00000046216 | ENSMUSP00000145558 | Sprouty-related, EVH1 domain-containing protein 3; Tyrosine kinase substrate that inhibits growth-factor- mediated activation of MAP kinase. | Potassium channel tetramerisation domain-containing 14. | 0.455 |
Spred3 | Smim3 | ENSMUSP00000046216 | ENSMUSP00000039285 | Sprouty-related, EVH1 domain-containing protein 3; Tyrosine kinase substrate that inhibits growth-factor- mediated activation of MAP kinase. | Small integral membrane protein 3. | 0.562 |
Tmem184a | Kctd14 | ENSMUSP00000035399 | ENSMUSP00000145558 | Transmembrane protein 184A; Acts as a heparin receptor in vascular cells (By similarity). May be involved in vesicle transport in exocrine cells and Sertoli cells. Belongs to the TMEM184 family. | Potassium channel tetramerisation domain-containing 14. | 0.680 |