node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Cdcp3 | Dmbt1 | ENSMUSP00000061529 | ENSMUSP00000146685 | Putative DMBT1-like protein. | Deleted in malignant brain tumors 1 protein; May play roles in mucosal defense system and cellular immune defense. May play a role in liver regeneration. May be an important factor in fate decision and differentiation of transit-amplifying ductular (oval) cells within the hepatic lineage. May function as a binding protein in saliva for the regulation of taste sensation. May play a role as an opsonin receptor for SFTPD and SPAR in macrophage tissues throughout the body, including epithelial cells lining the gastrointestinal tract (By similarity). Required for terminal differentiation of [...] | 0.905 |
Cdcp3 | L3mbtl2 | ENSMUSP00000061529 | ENSMUSP00000133967 | Putative DMBT1-like protein. | Lethal(3)malignant brain tumor-like protein 2; Putative Polycomb group (PcG) protein. PcG proteins maintain the transcriptionally repressive state of genes, probably via a modification of chromatin, rendering it heritably changed in its expressibility. Its association with a chromatin-remodeling complex suggests that it may contribute to prevent expression of genes that trigger the cell into mitosis. Binds to monomethylated and dimethylated 'Lys-20' on histone H4. Binds histone H3 peptides that are monomethylated or dimethylated on 'Lys-4', 'Lys-9' or 'Lys-27' (By similarity). | 0.432 |
Cdcp3 | Ppp1r37 | ENSMUSP00000061529 | ENSMUSP00000060233 | Putative DMBT1-like protein. | Protein phosphatase 1 regulatory subunit 37; Inhibits phosphatase activity of protein phosphatase 1 (PP1) complexes; Belongs to the PPP1R37 family. | 0.523 |
Cdcp3 | Rbpjl | ENSMUSP00000061529 | ENSMUSP00000017151 | Putative DMBT1-like protein. | Recombining binding protein suppressor of hairless-like protein; Putative transcription factor, which cooperates with EBNA2 to activate transcription; Belongs to the Su(H) family. | 0.436 |
Cdcp3 | Rnf216 | ENSMUSP00000061529 | ENSMUSP00000143705 | Putative DMBT1-like protein. | E3 ubiquitin-protein ligase RNF216; Acts as an E3 ubiquitin ligase, which accepts ubiquitin from specific E2 ubiquitin-conjugating enzymes, and then transfers it to substrates promoting their degradation by the proteasome. Promotes degradation of TRAF3, TLR4 and TLR9. Contributes to the regulation of antiviral responses. Down-regulates activation of NF-kappa-B, IRF3 activation and IFNB production. Promotes TNF and RIP mediated apoptosis. | 0.437 |
Cdcp3 | Sbp | ENSMUSP00000061529 | ENSMUSP00000138219 | Putative DMBT1-like protein. | Prostatic spermine-binding protein; This protein seems to be functional equivalent to rat prostatic spermine-binding protein, which is involved in polyamine binding. | 0.716 |
Cdcp3 | Tcaf3 | ENSMUSP00000061529 | ENSMUSP00000064060 | Putative DMBT1-like protein. | TRPM8 channel-associated factor 3; May play a role in the regulation of the cation channel TRPM8 activity. | 0.660 |
Cdcp3 | Try5 | ENSMUSP00000061529 | ENSMUSP00000064498 | Putative DMBT1-like protein. | Trypsinogen 9; Belongs to the peptidase S1 family. | 0.406 |
Cdcp3 | Upb1 | ENSMUSP00000061529 | ENSMUSP00000049342 | Putative DMBT1-like protein. | Beta-ureidopropionase; Catalyzes a late step in pyrimidine degradation. Converts N- carbamoyl-beta-alanine (3-ureidopropanoate) into beta-alanine, ammonia and carbon dioxide. Likewise, converts N-carbamoyl-beta- aminoisobutyrate (3-ureidoisobutyrate) into beta-aminoisobutyrate, ammonia and carbon dioxide; Belongs to the carbon-nitrogen hydrolase superfamily. BUP family. | 0.535 |
Dmbt1 | Cdcp3 | ENSMUSP00000146685 | ENSMUSP00000061529 | Deleted in malignant brain tumors 1 protein; May play roles in mucosal defense system and cellular immune defense. May play a role in liver regeneration. May be an important factor in fate decision and differentiation of transit-amplifying ductular (oval) cells within the hepatic lineage. May function as a binding protein in saliva for the regulation of taste sensation. May play a role as an opsonin receptor for SFTPD and SPAR in macrophage tissues throughout the body, including epithelial cells lining the gastrointestinal tract (By similarity). Required for terminal differentiation of [...] | Putative DMBT1-like protein. | 0.905 |
L3mbtl2 | Cdcp3 | ENSMUSP00000133967 | ENSMUSP00000061529 | Lethal(3)malignant brain tumor-like protein 2; Putative Polycomb group (PcG) protein. PcG proteins maintain the transcriptionally repressive state of genes, probably via a modification of chromatin, rendering it heritably changed in its expressibility. Its association with a chromatin-remodeling complex suggests that it may contribute to prevent expression of genes that trigger the cell into mitosis. Binds to monomethylated and dimethylated 'Lys-20' on histone H4. Binds histone H3 peptides that are monomethylated or dimethylated on 'Lys-4', 'Lys-9' or 'Lys-27' (By similarity). | Putative DMBT1-like protein. | 0.432 |
Ppp1r37 | Cdcp3 | ENSMUSP00000060233 | ENSMUSP00000061529 | Protein phosphatase 1 regulatory subunit 37; Inhibits phosphatase activity of protein phosphatase 1 (PP1) complexes; Belongs to the PPP1R37 family. | Putative DMBT1-like protein. | 0.523 |
Rbpjl | Cdcp3 | ENSMUSP00000017151 | ENSMUSP00000061529 | Recombining binding protein suppressor of hairless-like protein; Putative transcription factor, which cooperates with EBNA2 to activate transcription; Belongs to the Su(H) family. | Putative DMBT1-like protein. | 0.436 |
Rnf216 | Cdcp3 | ENSMUSP00000143705 | ENSMUSP00000061529 | E3 ubiquitin-protein ligase RNF216; Acts as an E3 ubiquitin ligase, which accepts ubiquitin from specific E2 ubiquitin-conjugating enzymes, and then transfers it to substrates promoting their degradation by the proteasome. Promotes degradation of TRAF3, TLR4 and TLR9. Contributes to the regulation of antiviral responses. Down-regulates activation of NF-kappa-B, IRF3 activation and IFNB production. Promotes TNF and RIP mediated apoptosis. | Putative DMBT1-like protein. | 0.437 |
Sbp | Cdcp3 | ENSMUSP00000138219 | ENSMUSP00000061529 | Prostatic spermine-binding protein; This protein seems to be functional equivalent to rat prostatic spermine-binding protein, which is involved in polyamine binding. | Putative DMBT1-like protein. | 0.716 |
Sbp | Tcaf3 | ENSMUSP00000138219 | ENSMUSP00000064060 | Prostatic spermine-binding protein; This protein seems to be functional equivalent to rat prostatic spermine-binding protein, which is involved in polyamine binding. | TRPM8 channel-associated factor 3; May play a role in the regulation of the cation channel TRPM8 activity. | 0.644 |
Tcaf3 | Cdcp3 | ENSMUSP00000064060 | ENSMUSP00000061529 | TRPM8 channel-associated factor 3; May play a role in the regulation of the cation channel TRPM8 activity. | Putative DMBT1-like protein. | 0.660 |
Tcaf3 | Sbp | ENSMUSP00000064060 | ENSMUSP00000138219 | TRPM8 channel-associated factor 3; May play a role in the regulation of the cation channel TRPM8 activity. | Prostatic spermine-binding protein; This protein seems to be functional equivalent to rat prostatic spermine-binding protein, which is involved in polyamine binding. | 0.644 |
Try5 | Cdcp3 | ENSMUSP00000064498 | ENSMUSP00000061529 | Trypsinogen 9; Belongs to the peptidase S1 family. | Putative DMBT1-like protein. | 0.406 |
Upb1 | Cdcp3 | ENSMUSP00000049342 | ENSMUSP00000061529 | Beta-ureidopropionase; Catalyzes a late step in pyrimidine degradation. Converts N- carbamoyl-beta-alanine (3-ureidopropanoate) into beta-alanine, ammonia and carbon dioxide. Likewise, converts N-carbamoyl-beta- aminoisobutyrate (3-ureidoisobutyrate) into beta-aminoisobutyrate, ammonia and carbon dioxide; Belongs to the carbon-nitrogen hydrolase superfamily. BUP family. | Putative DMBT1-like protein. | 0.535 |