Lrtm1 protein (mouse) - STRING interaction network

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Lrtm1

Leucine-rich repeat and transmembrane domain-containing protein 1. (356 aa)

Predicted Functional Partners:

Corin

0.635

Clstn2

0.521

Tmem220

0.484

Sebox

0.470

Arhgap28

0.434

Lmx1a

0.429

Ccl3

0.420

Pde6h

0.418

Erc2

0.414

Adprhl1

0.413

Your Current Organism:

Mus musculus

NCBI taxonomy Id: 10090
Other names: LK3 transgenic mice, M. musculus, Mus sp. 129SV, house mouse, mouse, nude mice, transgenic mice

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Adprhl1	Lrtm1	ENSMUSP00000033825	ENSMUSP00000061828	[Protein ADP-ribosylarginine] hydrolase-like protein 1; Seems not to catalyse the hydrolysis of O-acetyl-ADP-ribose.	Leucine-rich repeat and transmembrane domain-containing protein 1.	0.413
Arhgap28	Lrtm1	ENSMUSP00000024840	ENSMUSP00000061828	Rho GTPase-activating protein 28; GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state.	Leucine-rich repeat and transmembrane domain-containing protein 1.	0.434
Ccl3	Lrtm1	ENSMUSP00000001008	ENSMUSP00000061828	C-C motif chemokine 3; Monokine with inflammatory, pyrogenic and chemokinetic properties. Has a potent chemotactic activity for eosinophils. Binding to a high-affinity receptor activates calcium release in neutrophils; Belongs to the intercrine beta (chemokine CC) family.	Leucine-rich repeat and transmembrane domain-containing protein 1.	0.420
Clstn2	Lrtm1	ENSMUSP00000035027	ENSMUSP00000061828	Calsyntenin-2; May modulate calcium-mediated postsynaptic signals.	Leucine-rich repeat and transmembrane domain-containing protein 1.	0.521
Corin	Lmx1a	ENSMUSP00000005352	ENSMUSP00000028003	Atrial natriuretic peptide-converting enzyme, activated protease fragment; Serine-type endopeptidase involved in atrial natriuretic peptide hormone (NPPA) processing. Converts through proteolytic cleavage the non-functional propeptide NPPA into the active hormone, thereby regulating blood pressure in heart and promoting natriuresis, diuresis and vasodilation. Proteolytic cleavage of pro-NPPA also plays a role in female pregnancy by promoting trophoblast invasion and spiral artery remodeling in uterus. Also acts as a regulator of sodium reabsorption in kidney. May also process pro-NPPB [...]	LIM homeobox transcription factor 1-alpha; Acts as a transcriptional activator by binding to an A/T-rich sequence, the FLAT element, in the insulin gene promoter. Required for development of the roof plate and, in turn, for specification of dorsal cell fates in the CNS and developing vertebrae.	0.678
Corin	Lrtm1	ENSMUSP00000005352	ENSMUSP00000061828	Atrial natriuretic peptide-converting enzyme, activated protease fragment; Serine-type endopeptidase involved in atrial natriuretic peptide hormone (NPPA) processing. Converts through proteolytic cleavage the non-functional propeptide NPPA into the active hormone, thereby regulating blood pressure in heart and promoting natriuresis, diuresis and vasodilation. Proteolytic cleavage of pro-NPPA also plays a role in female pregnancy by promoting trophoblast invasion and spiral artery remodeling in uterus. Also acts as a regulator of sodium reabsorption in kidney. May also process pro-NPPB [...]	Leucine-rich repeat and transmembrane domain-containing protein 1.	0.635
Erc2	Lrtm1	ENSMUSP00000087773	ENSMUSP00000061828	ERC protein 2; Thought to be involved in the organization of the cytomatrix at the nerve terminals active zone (CAZ) which regulates neurotransmitter release. Seems to act together with BSN. May recruit liprin-alpha proteins to the CAZ.	Leucine-rich repeat and transmembrane domain-containing protein 1.	0.414
Lmx1a	Corin	ENSMUSP00000028003	ENSMUSP00000005352	LIM homeobox transcription factor 1-alpha; Acts as a transcriptional activator by binding to an A/T-rich sequence, the FLAT element, in the insulin gene promoter. Required for development of the roof plate and, in turn, for specification of dorsal cell fates in the CNS and developing vertebrae.	Atrial natriuretic peptide-converting enzyme, activated protease fragment; Serine-type endopeptidase involved in atrial natriuretic peptide hormone (NPPA) processing. Converts through proteolytic cleavage the non-functional propeptide NPPA into the active hormone, thereby regulating blood pressure in heart and promoting natriuresis, diuresis and vasodilation. Proteolytic cleavage of pro-NPPA also plays a role in female pregnancy by promoting trophoblast invasion and spiral artery remodeling in uterus. Also acts as a regulator of sodium reabsorption in kidney. May also process pro-NPPB [...]	0.678
Lmx1a	Lrtm1	ENSMUSP00000028003	ENSMUSP00000061828	LIM homeobox transcription factor 1-alpha; Acts as a transcriptional activator by binding to an A/T-rich sequence, the FLAT element, in the insulin gene promoter. Required for development of the roof plate and, in turn, for specification of dorsal cell fates in the CNS and developing vertebrae.	Leucine-rich repeat and transmembrane domain-containing protein 1.	0.429
Lrtm1	Adprhl1	ENSMUSP00000061828	ENSMUSP00000033825	Leucine-rich repeat and transmembrane domain-containing protein 1.	[Protein ADP-ribosylarginine] hydrolase-like protein 1; Seems not to catalyse the hydrolysis of O-acetyl-ADP-ribose.	0.413
Lrtm1	Arhgap28	ENSMUSP00000061828	ENSMUSP00000024840	Leucine-rich repeat and transmembrane domain-containing protein 1.	Rho GTPase-activating protein 28; GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state.	0.434
Lrtm1	Ccl3	ENSMUSP00000061828	ENSMUSP00000001008	Leucine-rich repeat and transmembrane domain-containing protein 1.	C-C motif chemokine 3; Monokine with inflammatory, pyrogenic and chemokinetic properties. Has a potent chemotactic activity for eosinophils. Binding to a high-affinity receptor activates calcium release in neutrophils; Belongs to the intercrine beta (chemokine CC) family.	0.420
Lrtm1	Clstn2	ENSMUSP00000061828	ENSMUSP00000035027	Leucine-rich repeat and transmembrane domain-containing protein 1.	Calsyntenin-2; May modulate calcium-mediated postsynaptic signals.	0.521
Lrtm1	Corin	ENSMUSP00000061828	ENSMUSP00000005352	Leucine-rich repeat and transmembrane domain-containing protein 1.	Atrial natriuretic peptide-converting enzyme, activated protease fragment; Serine-type endopeptidase involved in atrial natriuretic peptide hormone (NPPA) processing. Converts through proteolytic cleavage the non-functional propeptide NPPA into the active hormone, thereby regulating blood pressure in heart and promoting natriuresis, diuresis and vasodilation. Proteolytic cleavage of pro-NPPA also plays a role in female pregnancy by promoting trophoblast invasion and spiral artery remodeling in uterus. Also acts as a regulator of sodium reabsorption in kidney. May also process pro-NPPB [...]	0.635
Lrtm1	Erc2	ENSMUSP00000061828	ENSMUSP00000087773	Leucine-rich repeat and transmembrane domain-containing protein 1.	ERC protein 2; Thought to be involved in the organization of the cytomatrix at the nerve terminals active zone (CAZ) which regulates neurotransmitter release. Seems to act together with BSN. May recruit liprin-alpha proteins to the CAZ.	0.414
Lrtm1	Lmx1a	ENSMUSP00000061828	ENSMUSP00000028003	Leucine-rich repeat and transmembrane domain-containing protein 1.	LIM homeobox transcription factor 1-alpha; Acts as a transcriptional activator by binding to an A/T-rich sequence, the FLAT element, in the insulin gene promoter. Required for development of the roof plate and, in turn, for specification of dorsal cell fates in the CNS and developing vertebrae.	0.429
Lrtm1	Pde6h	ENSMUSP00000061828	ENSMUSP00000119246	Leucine-rich repeat and transmembrane domain-containing protein 1.	Retinal cone rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma; Participates in processes of transmission and amplification of the visual signal. cGMP-PDEs are the effector molecules in G- protein-mediated phototransduction in vertebrate rods and cones; Belongs to the rod/cone cGMP-PDE gamma subunit family.	0.418
Lrtm1	Sebox	ENSMUSP00000061828	ENSMUSP00000001130	Leucine-rich repeat and transmembrane domain-containing protein 1.	Homeobox protein SEBOX; Probable transcription factor involved in the control of specification of mesoderm and endoderm; Belongs to the paired homeobox family.	0.470
Lrtm1	Tmem220	ENSMUSP00000061828	ENSMUSP00000078084	Leucine-rich repeat and transmembrane domain-containing protein 1.	Transmembrane protein 220.	0.484
Pde6h	Lrtm1	ENSMUSP00000119246	ENSMUSP00000061828	Retinal cone rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma; Participates in processes of transmission and amplification of the visual signal. cGMP-PDEs are the effector molecules in G- protein-mediated phototransduction in vertebrate rods and cones; Belongs to the rod/cone cGMP-PDE gamma subunit family.	Leucine-rich repeat and transmembrane domain-containing protein 1.	0.418