STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Ces2bCarboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. (556 aa)    
Predicted Functional Partners:
Cda
Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.
     
 0.916
Gusb
Beta-glucuronidase; Plays an important role in the degradation of dermatan and keratan sulfates.
    
 0.915
Ugt2b38
UDP glucuronosyltransferase 2 family, polypeptide B38.
   
 
 0.847
Vmn1r58
Vomeronasal type-1 receptor.
   
   0.813
Skint8
Selection and upkeep of intraepithelial T-cells protein 8; May act by engaging a cell surface molecule on immature T- cells in the embryonic thymus.
   
  
 0.813
Cpa6
Carboxypeptidase A6; May be involved in the proteolytic inactivation of enkephalins and neurotensin in some brain areas. May convert inactive angiotensin I into the biologically active angiotensin II. Releases a C-terminal amino acid, with preference for large hydrophobic C-terminal amino acids and shows only very weak activity toward small amino acids and histidine.
   
  
 0.812
Ugt1a1
UDP-glucuronosyltransferase 1-1; UDPGT is of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds.
     
 0.809
Ugt2b35
UDP-glucuronosyltransferase; Belongs to the UDP-glycosyltransferase family.
   
 
 0.798
Ugt2b37
UDP-glucuronosyltransferase; Belongs to the UDP-glycosyltransferase family.
   
 
 0.795
Ugt2b1
UDP-glucuronosyltransferase; Belongs to the UDP-glycosyltransferase family.
   
 
 0.794
Your Current Organism:
Mus musculus
NCBI taxonomy Id: 10090
Other names: LK3 transgenic mice, M. musculus, Mus sp. 129SV, house mouse, mouse, nude mice, transgenic mice
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