STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SpinklSerine protease inhibitor kazal-like protein, major form; Does not function as an inhibitor of trypsin, chymotrypsin, subtilisin or elastase. Binds sperm and enhances sperm motility. May act as a decapacitation factor, suppresses BSA-stimulated sperm capacitation and blocks sperm-oocyte interactions in vitro. (90 aa)    
Predicted Functional Partners:
Svs2
Seminal vesicle secretory protein 2.
   
  
 0.880
Svs4
Seminal vesicle secretory protein 4.
   
  
 0.821
Svs3a
Seminal vesicle secretory protein 3A; Component of the copulatory plug.
   
  
 0.819
Pate4
Prostate and testis expressed protein 4; Enhances sperm motility. Binds to calmodulin and inhibits calcium transport into spermatozoa. May modulate the function of nicotinic acetylcholine receptors.
   
  
 0.813
Svs6
Seminal vesicle secretory protein 6.
   
  
 0.805
Svs5
Seminal vesicle secretory protein 5.
   
  
 0.742
Sva
Seminal vesicle antigen.
   
  
 0.712
9530003J23Rik
RIKEN cDNA 9530003J23 gene; Belongs to the glycosyl hydrolase 22 family.
   
  
 0.680
Svs3b
Seminal vesicle secretory protein 3B.
   
  
 0.679
Ceacam10
Carcinoembryonic antigen-related cell adhesion molecule 10; May interact with other CEACAM proteins on the sperm surface. Belongs to the immunoglobulin superfamily. CEA family.
   
  
 0.659
Your Current Organism:
Mus musculus
NCBI taxonomy Id: 10090
Other names: LK3 transgenic mice, M. musculus, Mus sp. 129SV, house mouse, mouse, nude mice, transgenic mice
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