node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Arhgap25 | Dmrtb1 | ENSMUSP00000109267 | ENSMUSP00000064220 | Rho GTPase-activating protein 25; GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state. | Doublesex- and mab-3-related transcription factor B1; Belongs to the DMRT family. | 0.466 |
Dazl | Dmrtb1 | ENSMUSP00000010736 | ENSMUSP00000064220 | Deleted in azoospermia-like; RNA-binding protein, which is essential for gametogenesis in both males and females. Plays a central role during spermatogenesis. Acts by binding to the 3'-UTR of mRNA, specifically recognizing GUU triplets, and thereby regulating the translation of key transcripts. | Doublesex- and mab-3-related transcription factor B1; Belongs to the DMRT family. | 0.476 |
Dazl | Rbm46 | ENSMUSP00000010736 | ENSMUSP00000045511 | Deleted in azoospermia-like; RNA-binding protein, which is essential for gametogenesis in both males and females. Plays a central role during spermatogenesis. Acts by binding to the 3'-UTR of mRNA, specifically recognizing GUU triplets, and thereby regulating the translation of key transcripts. | Probable RNA-binding protein 46. | 0.521 |
Dazl | Sohlh1 | ENSMUSP00000010736 | ENSMUSP00000076253 | Deleted in azoospermia-like; RNA-binding protein, which is essential for gametogenesis in both males and females. Plays a central role during spermatogenesis. Acts by binding to the 3'-UTR of mRNA, specifically recognizing GUU triplets, and thereby regulating the translation of key transcripts. | Spermatogenesis- and oogenesis-specific basic helix-loop-helix-containing protein 1; Transcription regulator of both male and female germline differentiation. Suppresses genes involved in spermatogonial stem cells maintenance, and induces genes important for spermatogonial differentiation. Coordinates oocyte differentiation without affecting meiosis I. | 0.666 |
Dazl | Sohlh2 | ENSMUSP00000010736 | ENSMUSP00000029369 | Deleted in azoospermia-like; RNA-binding protein, which is essential for gametogenesis in both males and females. Plays a central role during spermatogenesis. Acts by binding to the 3'-UTR of mRNA, specifically recognizing GUU triplets, and thereby regulating the translation of key transcripts. | Spermatogenesis- and oogenesis-specific basic helix-loop-helix-containing protein 2; Transcription regulator of both male and female germline differentiation. Suppresses genes involved in spermatogonial stem cells maintenance, and induces genes important for spermatogonial differentiation. Coordinates oocyte differentiation without affecting meiosis I. | 0.775 |
Dazl | Stra8 | ENSMUSP00000010736 | ENSMUSP00000031876 | Deleted in azoospermia-like; RNA-binding protein, which is essential for gametogenesis in both males and females. Plays a central role during spermatogenesis. Acts by binding to the 3'-UTR of mRNA, specifically recognizing GUU triplets, and thereby regulating the translation of key transcripts. | Stimulated by retinoic acid gene 8 protein; Meiosis-inducer required for the transition into meiosis for both female and male germ cells. In female germ cells, required for premeiotic DNA replication and subsequent events in meiotic prophase. During spermatogenesis, next to its role in meiotic initiation, promotes (but is not required for) spermatogonial differentiation. Can associate with DNA (possibly in an indirect manner), and in vitro can activate DNA transcription. | 0.891 |
Dmrtb1 | Arhgap25 | ENSMUSP00000064220 | ENSMUSP00000109267 | Doublesex- and mab-3-related transcription factor B1; Belongs to the DMRT family. | Rho GTPase-activating protein 25; GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state. | 0.466 |
Dmrtb1 | Dazl | ENSMUSP00000064220 | ENSMUSP00000010736 | Doublesex- and mab-3-related transcription factor B1; Belongs to the DMRT family. | Deleted in azoospermia-like; RNA-binding protein, which is essential for gametogenesis in both males and females. Plays a central role during spermatogenesis. Acts by binding to the 3'-UTR of mRNA, specifically recognizing GUU triplets, and thereby regulating the translation of key transcripts. | 0.476 |
Dmrtb1 | Fmr1nb | ENSMUSP00000064220 | ENSMUSP00000071748 | Doublesex- and mab-3-related transcription factor B1; Belongs to the DMRT family. | Fragile X mental retardation 1 neighbor protein. | 0.501 |
Dmrtb1 | Rbm46 | ENSMUSP00000064220 | ENSMUSP00000045511 | Doublesex- and mab-3-related transcription factor B1; Belongs to the DMRT family. | Probable RNA-binding protein 46. | 0.659 |
Dmrtb1 | Sohlh1 | ENSMUSP00000064220 | ENSMUSP00000076253 | Doublesex- and mab-3-related transcription factor B1; Belongs to the DMRT family. | Spermatogenesis- and oogenesis-specific basic helix-loop-helix-containing protein 1; Transcription regulator of both male and female germline differentiation. Suppresses genes involved in spermatogonial stem cells maintenance, and induces genes important for spermatogonial differentiation. Coordinates oocyte differentiation without affecting meiosis I. | 0.559 |
Dmrtb1 | Sohlh2 | ENSMUSP00000064220 | ENSMUSP00000029369 | Doublesex- and mab-3-related transcription factor B1; Belongs to the DMRT family. | Spermatogenesis- and oogenesis-specific basic helix-loop-helix-containing protein 2; Transcription regulator of both male and female germline differentiation. Suppresses genes involved in spermatogonial stem cells maintenance, and induces genes important for spermatogonial differentiation. Coordinates oocyte differentiation without affecting meiosis I. | 0.544 |
Dmrtb1 | Stra8 | ENSMUSP00000064220 | ENSMUSP00000031876 | Doublesex- and mab-3-related transcription factor B1; Belongs to the DMRT family. | Stimulated by retinoic acid gene 8 protein; Meiosis-inducer required for the transition into meiosis for both female and male germ cells. In female germ cells, required for premeiotic DNA replication and subsequent events in meiotic prophase. During spermatogenesis, next to its role in meiotic initiation, promotes (but is not required for) spermatogonial differentiation. Can associate with DNA (possibly in an indirect manner), and in vitro can activate DNA transcription. | 0.604 |
Dmrtb1 | Swt1 | ENSMUSP00000064220 | ENSMUSP00000067516 | Doublesex- and mab-3-related transcription factor B1; Belongs to the DMRT family. | Transcriptional protein SWT1. | 0.488 |
Dmrtb1 | Tex36 | ENSMUSP00000064220 | ENSMUSP00000033275 | Doublesex- and mab-3-related transcription factor B1; Belongs to the DMRT family. | Testis-expressed 36. | 0.476 |
Dmrtb1 | Triml2 | ENSMUSP00000064220 | ENSMUSP00000148196 | Doublesex- and mab-3-related transcription factor B1; Belongs to the DMRT family. | Tripartite motif family-like 2. | 0.481 |
Fmr1nb | Dmrtb1 | ENSMUSP00000071748 | ENSMUSP00000064220 | Fragile X mental retardation 1 neighbor protein. | Doublesex- and mab-3-related transcription factor B1; Belongs to the DMRT family. | 0.501 |
Fmr1nb | Swt1 | ENSMUSP00000071748 | ENSMUSP00000067516 | Fragile X mental retardation 1 neighbor protein. | Transcriptional protein SWT1. | 0.592 |
Fmr1nb | Triml2 | ENSMUSP00000071748 | ENSMUSP00000148196 | Fragile X mental retardation 1 neighbor protein. | Tripartite motif family-like 2. | 0.564 |
Rbm46 | Dazl | ENSMUSP00000045511 | ENSMUSP00000010736 | Probable RNA-binding protein 46. | Deleted in azoospermia-like; RNA-binding protein, which is essential for gametogenesis in both males and females. Plays a central role during spermatogenesis. Acts by binding to the 3'-UTR of mRNA, specifically recognizing GUU triplets, and thereby regulating the translation of key transcripts. | 0.521 |