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Alas2 protein (mouse) - STRING interaction network
"Alas2" - 5-aminolevulinate synthase, erythroid-specific, mitochondrial in Mus musculus
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second shell of interactors
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proteins of unknown 3D structure
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
Alas25-aminolevulinate synthase, erythroid-specific, mitochondrial; Aminolevulinic acid synthase 2, erythroid (587 aa)    
Predicted Functional Partners:
Alad
Delta-aminolevulinic acid dehydratase; Catalyzes an early step in the biosynthesis of tetrapyrroles. Binds two molecules of 5-aminolevulinate per subunit, each at a distinct site, and catalyzes their condensation to form porphobilinogen (By similarity); Belongs to the ALAD family (330 aa)
   
 
  0.977
Fech
Ferrochelatase, mitochondrial; Catalyzes the ferrous insertion into protoporphyrin IX (422 aa)
   
   
  0.922
Tha1
Threonine aldolase 1 (400 aa)
   
  0.920
Shmt2
Serine hydroxymethyltransferase; Interconversion of serine and glycine; Belongs to the SHMT family (504 aa)
   
 
  0.920
Agxt2
Alanine--glyoxylate aminotransferase 2, mitochondrial; Can metabolize asymmetric dimethylarginine (ADMA) via transamination to alpha-keto-delta-(NN-dimethylguanidino) valeric acid (DMGV). ADMA is a potent inhibitor of nitric-oxide (NO) synthase, and this activity provides mechanism through which the kidney regulates blood pressure (541 aa)
     
 
  0.920
Dao
D-amino-acid oxidase; Regulates the level of the neuromodulator D-serine in the brain. Has high activity towards D-DOPA and contributes to dopamine synthesis. Could act as a detoxifying agent which removes D-amino acids accumulated during aging. Acts on a variety of D- amino acids with a preference for those having small hydrophobic side chains followed by those bearing polar, aromatic, and basic groups. Does not act on acidic amino acids (345 aa)
   
 
  0.918
Shmt1
Serine hydroxymethyltransferase, cytosolic; Interconversion of serine and glycine (478 aa)
   
 
  0.918
Gldc
Glycine dehydrogenase (decarboxylating), mitochondrial; The glycine cleavage system catalyzes the degradation of glycine. The P protein (GLDC) binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein (GCSH) (By similarity); Belongs to the GcvP family (1025 aa)
     
 
  0.915
Sardh
Sarcosine dehydrogenase, mitochondrial; Sarcosine dehydrogenase; Belongs to the GcvT family (919 aa)
     
 
  0.914
Pipox
Peroxisomal sarcosine oxidase; Metabolizes sarcosine, L-pipecolic acid and L-proline (390 aa)
   
 
  0.913
Your Current Organism:
Mus musculus
NCBI taxonomy Id: 10090
Other names: LK3 transgenic mice, M. musculus, Mus muscaris, Mus musculus, Mus sp. 129SV, house mouse, mouse, nude mice, transgenic mice
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