Lce3a protein (mouse) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

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Gene Fusion

Cooccurrence

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[Homology]

Score

Lce3a

Late cornified envelope 3A. (98 aa)

Predicted Functional Partners:

Lce3b

0.870

Lce3f

0.857

Krt4

0.731

Sprr3

0.712

Lce3c

0.711

Serpinb3a

0.707

Defb4

0.672

Lce3e

0.660

Sprr2a1

0.657

Lce1m

0.617

Your Current Organism:

Mus musculus

NCBI taxonomy Id: 10090
Other names: LK3 transgenic mice, M. musculus, Mus sp. 129SV, house mouse, mouse, nude mice, transgenic mice

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Defb4	Krt4	ENSMUSP00000079808	ENSMUSP00000023797	Beta-defensin 4; Exhibits antimicrobial activity against Gram-negative bacteria and Gram-positive bacteria. May act as a ligand for C-C chemokine receptor CCR6. Can bind to mouse (but not human) CCR6 and induce chemotactic activity of CCR6-expressing cells.	Keratin, type II cytoskeletal 4.	0.561
Defb4	Lce3a	ENSMUSP00000079808	ENSMUSP00000066468	Beta-defensin 4; Exhibits antimicrobial activity against Gram-negative bacteria and Gram-positive bacteria. May act as a ligand for C-C chemokine receptor CCR6. Can bind to mouse (but not human) CCR6 and induce chemotactic activity of CCR6-expressing cells.	Late cornified envelope 3A.	0.672
Defb4	Lce3b	ENSMUSP00000079808	ENSMUSP00000046325	Beta-defensin 4; Exhibits antimicrobial activity against Gram-negative bacteria and Gram-positive bacteria. May act as a ligand for C-C chemokine receptor CCR6. Can bind to mouse (but not human) CCR6 and induce chemotactic activity of CCR6-expressing cells.	Late cornified envelope 3B.	0.796
Defb4	Lce3c	ENSMUSP00000079808	ENSMUSP00000050666	Beta-defensin 4; Exhibits antimicrobial activity against Gram-negative bacteria and Gram-positive bacteria. May act as a ligand for C-C chemokine receptor CCR6. Can bind to mouse (but not human) CCR6 and induce chemotactic activity of CCR6-expressing cells.	Late cornified envelope 3C.	0.589
Defb4	Lce3e	ENSMUSP00000079808	ENSMUSP00000096484	Beta-defensin 4; Exhibits antimicrobial activity against Gram-negative bacteria and Gram-positive bacteria. May act as a ligand for C-C chemokine receptor CCR6. Can bind to mouse (but not human) CCR6 and induce chemotactic activity of CCR6-expressing cells.	Late cornified envelope 3E.	0.611
Defb4	Lce3f	ENSMUSP00000079808	ENSMUSP00000088375	Beta-defensin 4; Exhibits antimicrobial activity against Gram-negative bacteria and Gram-positive bacteria. May act as a ligand for C-C chemokine receptor CCR6. Can bind to mouse (but not human) CCR6 and induce chemotactic activity of CCR6-expressing cells.	Late cornified envelope 3F.	0.586
Defb4	Serpinb3a	ENSMUSP00000079808	ENSMUSP00000027567	Beta-defensin 4; Exhibits antimicrobial activity against Gram-negative bacteria and Gram-positive bacteria. May act as a ligand for C-C chemokine receptor CCR6. Can bind to mouse (but not human) CCR6 and induce chemotactic activity of CCR6-expressing cells.	Serine (or cysteine) peptidase inhibitor, clade B (ovalbumin), member 3A; Belongs to the serpin family.	0.656
Defb4	Sprr3	ENSMUSP00000079808	ENSMUSP00000056287	Beta-defensin 4; Exhibits antimicrobial activity against Gram-negative bacteria and Gram-positive bacteria. May act as a ligand for C-C chemokine receptor CCR6. Can bind to mouse (but not human) CCR6 and induce chemotactic activity of CCR6-expressing cells.	Small proline-rich protein 3; Cross-linked envelope protein of keratinocytes; Belongs to the cornifin (SPRR) family.	0.614
Krt4	Defb4	ENSMUSP00000023797	ENSMUSP00000079808	Keratin, type II cytoskeletal 4.	Beta-defensin 4; Exhibits antimicrobial activity against Gram-negative bacteria and Gram-positive bacteria. May act as a ligand for C-C chemokine receptor CCR6. Can bind to mouse (but not human) CCR6 and induce chemotactic activity of CCR6-expressing cells.	0.561
Krt4	Lce3a	ENSMUSP00000023797	ENSMUSP00000066468	Keratin, type II cytoskeletal 4.	Late cornified envelope 3A.	0.731
Krt4	Lce3c	ENSMUSP00000023797	ENSMUSP00000050666	Keratin, type II cytoskeletal 4.	Late cornified envelope 3C.	0.607
Krt4	Lce3f	ENSMUSP00000023797	ENSMUSP00000088375	Keratin, type II cytoskeletal 4.	Late cornified envelope 3F.	0.520
Krt4	Serpinb3a	ENSMUSP00000023797	ENSMUSP00000027567	Keratin, type II cytoskeletal 4.	Serine (or cysteine) peptidase inhibitor, clade B (ovalbumin), member 3A; Belongs to the serpin family.	0.566
Krt4	Sprr2a1	ENSMUSP00000023797	ENSMUSP00000083330	Keratin, type II cytoskeletal 4.	Small proline-rich protein 2A3; Cross-linked envelope protein of keratinocytes. It is a keratinocyte protein that first appears in the cell cytosol, but ultimately becomes cross-linked to membrane proteins by transglutaminase. All that results in the formation of an insoluble envelope beneath the plasma membrane (By similarity). Belongs to the cornifin (SPRR) family.	0.478
Krt4	Sprr3	ENSMUSP00000023797	ENSMUSP00000056287	Keratin, type II cytoskeletal 4.	Small proline-rich protein 3; Cross-linked envelope protein of keratinocytes; Belongs to the cornifin (SPRR) family.	0.804
Lce1m	Lce3a	ENSMUSP00000029520	ENSMUSP00000066468	Late cornified envelope 1M.	Late cornified envelope 3A.	0.617
Lce1m	Lce3b	ENSMUSP00000029520	ENSMUSP00000046325	Late cornified envelope 1M.	Late cornified envelope 3B.	0.442
Lce1m	Lce3c	ENSMUSP00000029520	ENSMUSP00000050666	Late cornified envelope 1M.	Late cornified envelope 3C.	0.477
Lce1m	Lce3f	ENSMUSP00000029520	ENSMUSP00000088375	Late cornified envelope 1M.	Late cornified envelope 3F.	0.530
Lce3a	Defb4	ENSMUSP00000066468	ENSMUSP00000079808	Late cornified envelope 3A.	Beta-defensin 4; Exhibits antimicrobial activity against Gram-negative bacteria and Gram-positive bacteria. May act as a ligand for C-C chemokine receptor CCR6. Can bind to mouse (but not human) CCR6 and induce chemotactic activity of CCR6-expressing cells.	0.672