Export your current network:
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of protiens in your network
Browse interactions in tabular form:
| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Ang2 | Ang4 | ENSMUSP00000154100 | ENSMUSP00000073525 | Angiogenin-2; Has ribonuclease activity (in vitro). Seems to lack angiogenic activity. | Angiogenin-4; Has bactericidal activity against E.faecalis and L.monocytogenes, but not against L.innocua and E.coli. Promotes angiogenesis (in vitro). Has low ribonuclease activity (in vitro). Promotes proliferation of melanoma cells, but not of endothelial cells or fibroblasts (in vitro). | 0.848 |
| Ang2 | Ang5 | ENSMUSP00000154100 | ENSMUSP00000067008 | Angiogenin-2; Has ribonuclease activity (in vitro). Seems to lack angiogenic activity. | Angiogenin-3; May promote vascularization of normal and malignant tissues (By similarity). Has low ribonuclease activity (in vitro). | 0.478 |
| Ang2 | Tek | ENSMUSP00000154100 | ENSMUSP00000099862 | Angiogenin-2; Has ribonuclease activity (in vitro). Seems to lack angiogenic activity. | Angiopoietin-1 receptor; Tyrosine-protein kinase that acts as cell-surface receptor for ANGPT1, ANGPT2 and ANGPT4 and regulates angiogenesis, endothelial cell survival, proliferation, migration, adhesion and cell spreading, reorganization of the actin cytoskeleton, but also maintenance of vascular quiescence. Has anti-inflammatory effects by preventing the leakage of proinflammatory plasma proteins and leukocytes from blood vessels. Required for normal angiogenesis and heart development during embryogenesis. Required for post-natal hematopoiesis. After birth, activates or inhibits angi [...] | 0.728 |
| Ang4 | Ang2 | ENSMUSP00000073525 | ENSMUSP00000154100 | Angiogenin-4; Has bactericidal activity against E.faecalis and L.monocytogenes, but not against L.innocua and E.coli. Promotes angiogenesis (in vitro). Has low ribonuclease activity (in vitro). Promotes proliferation of melanoma cells, but not of endothelial cells or fibroblasts (in vitro). | Angiogenin-2; Has ribonuclease activity (in vitro). Seems to lack angiogenic activity. | 0.848 |
| Ang4 | Ang5 | ENSMUSP00000073525 | ENSMUSP00000067008 | Angiogenin-4; Has bactericidal activity against E.faecalis and L.monocytogenes, but not against L.innocua and E.coli. Promotes angiogenesis (in vitro). Has low ribonuclease activity (in vitro). Promotes proliferation of melanoma cells, but not of endothelial cells or fibroblasts (in vitro). | Angiogenin-3; May promote vascularization of normal and malignant tissues (By similarity). Has low ribonuclease activity (in vitro). | 0.542 |
| Ang4 | Ang6 | ENSMUSP00000073525 | ENSMUSP00000094632 | Angiogenin-4; Has bactericidal activity against E.faecalis and L.monocytogenes, but not against L.innocua and E.coli. Promotes angiogenesis (in vitro). Has low ribonuclease activity (in vitro). Promotes proliferation of melanoma cells, but not of endothelial cells or fibroblasts (in vitro). | Angiogenin, ribonuclease A family, member 6; Belongs to the pancreatic ribonuclease family. | 0.783 |
| Ang4 | Tek | ENSMUSP00000073525 | ENSMUSP00000099862 | Angiogenin-4; Has bactericidal activity against E.faecalis and L.monocytogenes, but not against L.innocua and E.coli. Promotes angiogenesis (in vitro). Has low ribonuclease activity (in vitro). Promotes proliferation of melanoma cells, but not of endothelial cells or fibroblasts (in vitro). | Angiopoietin-1 receptor; Tyrosine-protein kinase that acts as cell-surface receptor for ANGPT1, ANGPT2 and ANGPT4 and regulates angiogenesis, endothelial cell survival, proliferation, migration, adhesion and cell spreading, reorganization of the actin cytoskeleton, but also maintenance of vascular quiescence. Has anti-inflammatory effects by preventing the leakage of proinflammatory plasma proteins and leukocytes from blood vessels. Required for normal angiogenesis and heart development during embryogenesis. Required for post-natal hematopoiesis. After birth, activates or inhibits angi [...] | 0.410 |
| Ang4 | Tyk2 | ENSMUSP00000073525 | ENSMUSP00000150354 | Angiogenin-4; Has bactericidal activity against E.faecalis and L.monocytogenes, but not against L.innocua and E.coli. Promotes angiogenesis (in vitro). Has low ribonuclease activity (in vitro). Promotes proliferation of melanoma cells, but not of endothelial cells or fibroblasts (in vitro). | Non-receptor tyrosine-protein kinase TYK2; Involved in intracellular signal transduction by amplifying type I and type II IFN signaling. Phosphorylates the interferon- alpha/beta receptor alpha chain. Plays an essential role in promoting selective immune responses, including innate host defense mechanisms and specific antiviral activities. | 0.427 |
| Ang5 | Ang2 | ENSMUSP00000067008 | ENSMUSP00000154100 | Angiogenin-3; May promote vascularization of normal and malignant tissues (By similarity). Has low ribonuclease activity (in vitro). | Angiogenin-2; Has ribonuclease activity (in vitro). Seems to lack angiogenic activity. | 0.478 |
| Ang5 | Ang4 | ENSMUSP00000067008 | ENSMUSP00000073525 | Angiogenin-3; May promote vascularization of normal and malignant tissues (By similarity). Has low ribonuclease activity (in vitro). | Angiogenin-4; Has bactericidal activity against E.faecalis and L.monocytogenes, but not against L.innocua and E.coli. Promotes angiogenesis (in vitro). Has low ribonuclease activity (in vitro). Promotes proliferation of melanoma cells, but not of endothelial cells or fibroblasts (in vitro). | 0.542 |
| Ang5 | Ang6 | ENSMUSP00000067008 | ENSMUSP00000094632 | Angiogenin-3; May promote vascularization of normal and malignant tissues (By similarity). Has low ribonuclease activity (in vitro). | Angiogenin, ribonuclease A family, member 6; Belongs to the pancreatic ribonuclease family. | 0.805 |
| Ang5 | Fh1 | ENSMUSP00000067008 | ENSMUSP00000027810 | Angiogenin-3; May promote vascularization of normal and malignant tissues (By similarity). Has low ribonuclease activity (in vitro). | Fumarate hydratase, mitochondrial; Catalyzes the reversible stereospecific interconversion of fumarate to L-malate. Experiments in different species have demonstrated that specific isoforms of this protein act in defined pathways and favor one direction over the other (Probable). [Isoform Cytoplasmic]: Catalyzes the dehydration of L-malate to fumarate. Fumarate metabolism in the cytosol plays a role during urea cycle and arginine metabolism; fumarate being a by- product of the urea cycle and amino-acid catabolism. Also plays a role in DNA repair by promoting non-homologous end-joining [...] | 0.491 |
| Ang5 | Guf1 | ENSMUSP00000067008 | ENSMUSP00000084480 | Angiogenin-3; May promote vascularization of normal and malignant tissues (By similarity). Has low ribonuclease activity (in vitro). | Translation factor Guf1, mitochondrial; Promotes mitochondrial protein synthesis. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Binds to mitochondrial ribosomes in a GTP-dependent manner. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily. | 0.499 |
| Ang5 | Tek | ENSMUSP00000067008 | ENSMUSP00000099862 | Angiogenin-3; May promote vascularization of normal and malignant tissues (By similarity). Has low ribonuclease activity (in vitro). | Angiopoietin-1 receptor; Tyrosine-protein kinase that acts as cell-surface receptor for ANGPT1, ANGPT2 and ANGPT4 and regulates angiogenesis, endothelial cell survival, proliferation, migration, adhesion and cell spreading, reorganization of the actin cytoskeleton, but also maintenance of vascular quiescence. Has anti-inflammatory effects by preventing the leakage of proinflammatory plasma proteins and leukocytes from blood vessels. Required for normal angiogenesis and heart development during embryogenesis. Required for post-natal hematopoiesis. After birth, activates or inhibits angi [...] | 0.492 |
| Ang5 | Tyk2 | ENSMUSP00000067008 | ENSMUSP00000150354 | Angiogenin-3; May promote vascularization of normal and malignant tissues (By similarity). Has low ribonuclease activity (in vitro). | Non-receptor tyrosine-protein kinase TYK2; Involved in intracellular signal transduction by amplifying type I and type II IFN signaling. Phosphorylates the interferon- alpha/beta receptor alpha chain. Plays an essential role in promoting selective immune responses, including innate host defense mechanisms and specific antiviral activities. | 0.410 |
| Ang5 | Vill | ENSMUSP00000067008 | ENSMUSP00000061731 | Angiogenin-3; May promote vascularization of normal and malignant tissues (By similarity). Has low ribonuclease activity (in vitro). | Villin-like protein; Possible tumor suppressor. | 0.444 |
| Ang6 | Ang4 | ENSMUSP00000094632 | ENSMUSP00000073525 | Angiogenin, ribonuclease A family, member 6; Belongs to the pancreatic ribonuclease family. | Angiogenin-4; Has bactericidal activity against E.faecalis and L.monocytogenes, but not against L.innocua and E.coli. Promotes angiogenesis (in vitro). Has low ribonuclease activity (in vitro). Promotes proliferation of melanoma cells, but not of endothelial cells or fibroblasts (in vitro). | 0.783 |
| Ang6 | Ang5 | ENSMUSP00000094632 | ENSMUSP00000067008 | Angiogenin, ribonuclease A family, member 6; Belongs to the pancreatic ribonuclease family. | Angiogenin-3; May promote vascularization of normal and malignant tissues (By similarity). Has low ribonuclease activity (in vitro). | 0.805 |
| Fh1 | Ang5 | ENSMUSP00000027810 | ENSMUSP00000067008 | Fumarate hydratase, mitochondrial; Catalyzes the reversible stereospecific interconversion of fumarate to L-malate. Experiments in different species have demonstrated that specific isoforms of this protein act in defined pathways and favor one direction over the other (Probable). [Isoform Cytoplasmic]: Catalyzes the dehydration of L-malate to fumarate. Fumarate metabolism in the cytosol plays a role during urea cycle and arginine metabolism; fumarate being a by- product of the urea cycle and amino-acid catabolism. Also plays a role in DNA repair by promoting non-homologous end-joining [...] | Angiogenin-3; May promote vascularization of normal and malignant tissues (By similarity). Has low ribonuclease activity (in vitro). | 0.491 |
| Fh1 | Guf1 | ENSMUSP00000027810 | ENSMUSP00000084480 | Fumarate hydratase, mitochondrial; Catalyzes the reversible stereospecific interconversion of fumarate to L-malate. Experiments in different species have demonstrated that specific isoforms of this protein act in defined pathways and favor one direction over the other (Probable). [Isoform Cytoplasmic]: Catalyzes the dehydration of L-malate to fumarate. Fumarate metabolism in the cytosol plays a role during urea cycle and arginine metabolism; fumarate being a by- product of the urea cycle and amino-acid catabolism. Also plays a role in DNA repair by promoting non-homologous end-joining [...] | Translation factor Guf1, mitochondrial; Promotes mitochondrial protein synthesis. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Binds to mitochondrial ribosomes in a GTP-dependent manner. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily. | 0.937 |
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