node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Dus3l | Tbcel | ENSMUSP00000007747 | ENSMUSP00000067882 | tRNA-dihydrouridine(47) synthase [NAD(P)(+)]-like; Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs. | Tubulin-specific chaperone cofactor E-like protein; Acts as a regulator of tubulin stability. | 0.521 |
Mitd1 | Tbcel | ENSMUSP00000027257 | ENSMUSP00000067882 | MIT domain-containing protein 1; Required for efficient abscission at the end of cytokinesis, together with components of the ESCRT-III complex. | Tubulin-specific chaperone cofactor E-like protein; Acts as a regulator of tubulin stability. | 0.660 |
Prrc2b | Tbcel | ENSMUSP00000064892 | ENSMUSP00000067882 | Protein PRRC2B. | Tubulin-specific chaperone cofactor E-like protein; Acts as a regulator of tubulin stability. | 0.510 |
Rab11fip4 | Tbcel | ENSMUSP00000017783 | ENSMUSP00000067882 | Rab11 family-interacting protein 4; Acts as a regulator of endocytic traffic by participating in membrane delivery. Required for the abcission step in cytokinesis, possibly by acting as an 'address tag' delivering recycling endosome membranes to the cleavage furrow during late cytokinesis (By similarity). May play a role in differentiation during retinal development, in a Rab11-independent manner. | Tubulin-specific chaperone cofactor E-like protein; Acts as a regulator of tubulin stability. | 0.475 |
Tbca | Tbcb | ENSMUSP00000038781 | ENSMUSP00000006254 | Tubulin-specific chaperone A; Tubulin-folding protein; involved in the early step of the tubulin folding pathway; Belongs to the TBCA family. | Tubulin-folding cofactor B; Binds to alpha-tubulin folding intermediates after their interaction with cytosolic chaperonin in the pathway leading from newly synthesized tubulin to properly folded heterodimer (By similarity). Involved in regulation of tubulin heterodimer dissociation. May function as a negative regulator of axonal growth ; Belongs to the TBCB family. | 0.834 |
Tbca | Tbcc | ENSMUSP00000038781 | ENSMUSP00000048696 | Tubulin-specific chaperone A; Tubulin-folding protein; involved in the early step of the tubulin folding pathway; Belongs to the TBCA family. | Tubulin-specific chaperone C; Tubulin-folding protein; involved in the final step of the tubulin folding pathway. | 0.687 |
Tbca | Tbcd | ENSMUSP00000038781 | ENSMUSP00000099302 | Tubulin-specific chaperone A; Tubulin-folding protein; involved in the early step of the tubulin folding pathway; Belongs to the TBCA family. | Tubulin-specific chaperone D; Tubulin-folding protein implicated in the first step of the tubulin folding pathway and required for tubulin complex assembly. Involved in the regulation of microtubule polymerization or depolymerization, it modulates microtubule dynamics by capturing GTP- bound beta-tubulin (TUBB). Its ability to interact with beta tubulin is regulated via its interaction with ARL2. Acts as a GTPase-activating protein (GAP) for ARL2. Induces microtubule disruption in absence of ARL2. Increases degradation of beta tubulin, when overexpressed in polarized cells. Promotes ep [...] | 0.787 |
Tbca | Tbcel | ENSMUSP00000038781 | ENSMUSP00000067882 | Tubulin-specific chaperone A; Tubulin-folding protein; involved in the early step of the tubulin folding pathway; Belongs to the TBCA family. | Tubulin-specific chaperone cofactor E-like protein; Acts as a regulator of tubulin stability. | 0.651 |
Tbcb | Tbca | ENSMUSP00000006254 | ENSMUSP00000038781 | Tubulin-folding cofactor B; Binds to alpha-tubulin folding intermediates after their interaction with cytosolic chaperonin in the pathway leading from newly synthesized tubulin to properly folded heterodimer (By similarity). Involved in regulation of tubulin heterodimer dissociation. May function as a negative regulator of axonal growth ; Belongs to the TBCB family. | Tubulin-specific chaperone A; Tubulin-folding protein; involved in the early step of the tubulin folding pathway; Belongs to the TBCA family. | 0.834 |
Tbcb | Tbcc | ENSMUSP00000006254 | ENSMUSP00000048696 | Tubulin-folding cofactor B; Binds to alpha-tubulin folding intermediates after their interaction with cytosolic chaperonin in the pathway leading from newly synthesized tubulin to properly folded heterodimer (By similarity). Involved in regulation of tubulin heterodimer dissociation. May function as a negative regulator of axonal growth ; Belongs to the TBCB family. | Tubulin-specific chaperone C; Tubulin-folding protein; involved in the final step of the tubulin folding pathway. | 0.743 |
Tbcb | Tbcd | ENSMUSP00000006254 | ENSMUSP00000099302 | Tubulin-folding cofactor B; Binds to alpha-tubulin folding intermediates after their interaction with cytosolic chaperonin in the pathway leading from newly synthesized tubulin to properly folded heterodimer (By similarity). Involved in regulation of tubulin heterodimer dissociation. May function as a negative regulator of axonal growth ; Belongs to the TBCB family. | Tubulin-specific chaperone D; Tubulin-folding protein implicated in the first step of the tubulin folding pathway and required for tubulin complex assembly. Involved in the regulation of microtubule polymerization or depolymerization, it modulates microtubule dynamics by capturing GTP- bound beta-tubulin (TUBB). Its ability to interact with beta tubulin is regulated via its interaction with ARL2. Acts as a GTPase-activating protein (GAP) for ARL2. Induces microtubule disruption in absence of ARL2. Increases degradation of beta tubulin, when overexpressed in polarized cells. Promotes ep [...] | 0.883 |
Tbcb | Tbcel | ENSMUSP00000006254 | ENSMUSP00000067882 | Tubulin-folding cofactor B; Binds to alpha-tubulin folding intermediates after their interaction with cytosolic chaperonin in the pathway leading from newly synthesized tubulin to properly folded heterodimer (By similarity). Involved in regulation of tubulin heterodimer dissociation. May function as a negative regulator of axonal growth ; Belongs to the TBCB family. | Tubulin-specific chaperone cofactor E-like protein; Acts as a regulator of tubulin stability. | 0.654 |
Tbcc | Tbca | ENSMUSP00000048696 | ENSMUSP00000038781 | Tubulin-specific chaperone C; Tubulin-folding protein; involved in the final step of the tubulin folding pathway. | Tubulin-specific chaperone A; Tubulin-folding protein; involved in the early step of the tubulin folding pathway; Belongs to the TBCA family. | 0.687 |
Tbcc | Tbcb | ENSMUSP00000048696 | ENSMUSP00000006254 | Tubulin-specific chaperone C; Tubulin-folding protein; involved in the final step of the tubulin folding pathway. | Tubulin-folding cofactor B; Binds to alpha-tubulin folding intermediates after their interaction with cytosolic chaperonin in the pathway leading from newly synthesized tubulin to properly folded heterodimer (By similarity). Involved in regulation of tubulin heterodimer dissociation. May function as a negative regulator of axonal growth ; Belongs to the TBCB family. | 0.743 |
Tbcc | Tbcd | ENSMUSP00000048696 | ENSMUSP00000099302 | Tubulin-specific chaperone C; Tubulin-folding protein; involved in the final step of the tubulin folding pathway. | Tubulin-specific chaperone D; Tubulin-folding protein implicated in the first step of the tubulin folding pathway and required for tubulin complex assembly. Involved in the regulation of microtubule polymerization or depolymerization, it modulates microtubule dynamics by capturing GTP- bound beta-tubulin (TUBB). Its ability to interact with beta tubulin is regulated via its interaction with ARL2. Acts as a GTPase-activating protein (GAP) for ARL2. Induces microtubule disruption in absence of ARL2. Increases degradation of beta tubulin, when overexpressed in polarized cells. Promotes ep [...] | 0.832 |
Tbcc | Tbcel | ENSMUSP00000048696 | ENSMUSP00000067882 | Tubulin-specific chaperone C; Tubulin-folding protein; involved in the final step of the tubulin folding pathway. | Tubulin-specific chaperone cofactor E-like protein; Acts as a regulator of tubulin stability. | 0.715 |
Tbcd | Tbca | ENSMUSP00000099302 | ENSMUSP00000038781 | Tubulin-specific chaperone D; Tubulin-folding protein implicated in the first step of the tubulin folding pathway and required for tubulin complex assembly. Involved in the regulation of microtubule polymerization or depolymerization, it modulates microtubule dynamics by capturing GTP- bound beta-tubulin (TUBB). Its ability to interact with beta tubulin is regulated via its interaction with ARL2. Acts as a GTPase-activating protein (GAP) for ARL2. Induces microtubule disruption in absence of ARL2. Increases degradation of beta tubulin, when overexpressed in polarized cells. Promotes ep [...] | Tubulin-specific chaperone A; Tubulin-folding protein; involved in the early step of the tubulin folding pathway; Belongs to the TBCA family. | 0.787 |
Tbcd | Tbcb | ENSMUSP00000099302 | ENSMUSP00000006254 | Tubulin-specific chaperone D; Tubulin-folding protein implicated in the first step of the tubulin folding pathway and required for tubulin complex assembly. Involved in the regulation of microtubule polymerization or depolymerization, it modulates microtubule dynamics by capturing GTP- bound beta-tubulin (TUBB). Its ability to interact with beta tubulin is regulated via its interaction with ARL2. Acts as a GTPase-activating protein (GAP) for ARL2. Induces microtubule disruption in absence of ARL2. Increases degradation of beta tubulin, when overexpressed in polarized cells. Promotes ep [...] | Tubulin-folding cofactor B; Binds to alpha-tubulin folding intermediates after their interaction with cytosolic chaperonin in the pathway leading from newly synthesized tubulin to properly folded heterodimer (By similarity). Involved in regulation of tubulin heterodimer dissociation. May function as a negative regulator of axonal growth ; Belongs to the TBCB family. | 0.883 |
Tbcd | Tbcc | ENSMUSP00000099302 | ENSMUSP00000048696 | Tubulin-specific chaperone D; Tubulin-folding protein implicated in the first step of the tubulin folding pathway and required for tubulin complex assembly. Involved in the regulation of microtubule polymerization or depolymerization, it modulates microtubule dynamics by capturing GTP- bound beta-tubulin (TUBB). Its ability to interact with beta tubulin is regulated via its interaction with ARL2. Acts as a GTPase-activating protein (GAP) for ARL2. Induces microtubule disruption in absence of ARL2. Increases degradation of beta tubulin, when overexpressed in polarized cells. Promotes ep [...] | Tubulin-specific chaperone C; Tubulin-folding protein; involved in the final step of the tubulin folding pathway. | 0.832 |
Tbcd | Tbcel | ENSMUSP00000099302 | ENSMUSP00000067882 | Tubulin-specific chaperone D; Tubulin-folding protein implicated in the first step of the tubulin folding pathway and required for tubulin complex assembly. Involved in the regulation of microtubule polymerization or depolymerization, it modulates microtubule dynamics by capturing GTP- bound beta-tubulin (TUBB). Its ability to interact with beta tubulin is regulated via its interaction with ARL2. Acts as a GTPase-activating protein (GAP) for ARL2. Induces microtubule disruption in absence of ARL2. Increases degradation of beta tubulin, when overexpressed in polarized cells. Promotes ep [...] | Tubulin-specific chaperone cofactor E-like protein; Acts as a regulator of tubulin stability. | 0.652 |