STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Depp1Protein DEPP1; Acts as a critical modulator of FOXO3-induced autophagy via increased cellular ROS. (205 aa)    
Predicted Functional Partners:
Wfdc13
WAP four-disulfide core domain protein 13; Putative acid-stable proteinase inhibitor.
      
 0.526
Crnn
Cornulin.
      
 0.515
Rptn
Repetin; Involved in the cornified cell envelope formation. Multifunctional epidermal matrix protein; Belongs to the S100-fused protein family.
      
 0.512
C130074G19Rik
Uncharacterized protein C1orf115 homolog.
   
  
 0.493
Actl11
Actin-like 11; Belongs to the actin family.
      
 0.489
Ccdc171
Coiled-coil domain-containing protein 171.
      
 0.479
Wdr38
WD repeat-containing protein 38.
      
 0.461
Gm21830
Predicted gene, 21830.
      
 0.457
Spint4
Kunitz-type protease inhibitor 4.
      
 0.440
Fam71b
Protein FAM71B; May be involved in RNA biogenesis.
      
 0.412
Your Current Organism:
Mus musculus
NCBI taxonomy Id: 10090
Other names: LK3 transgenic mice, M. musculus, Mus sp. 129SV, house mouse, mouse, nude mice, transgenic mice
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