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Amy1 protein (mouse) - STRING interaction network
"Amy1" - Amylase 1, salivary in Mus musculus
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Amy1Amylase 1, salivary (511 aa)    
Predicted Functional Partners:
Pygl
Liver glycogen phosphorylase; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity) (850 aa)
   
  0.987
Pygm
Muscle glycogen phosphorylase; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (842 aa)
   
  0.985
Pygb
Brain glycogen phosphorylase; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties (By similarity) (843 aa)
   
  0.985
Gbe1
Glucan (1,4-alpha-), branching enzyme 1; Required for sufficient glycogen accumulation. The alpha 1-6 branches of glycogen play an important role in increasing the solubility of the molecule and, consequently, in reducing the osmotic pressure within cells (By similarity) (702 aa)
   
 
  0.971
Agl
Amylo-1,6-glucosidase, 4-alpha-glucanotransferase (1532 aa)
   
  0.965
Mgam
Maltase-glucoamylase (1827 aa)
   
 
  0.957
Sis
Sucrase isomaltase (alpha-glucosidase) (1818 aa)
   
 
  0.956
Amy2a4
Amylase 2a4 (508 aa)
   
   
0.802
Gys2
Glycogen synthase 2; Transfers the glycosyl residue from UDP-Glc to the non- reducing end of alpha-1,4-glucan (704 aa)
   
  0.680
Gne
Glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase; Regulates and initiates biosynthesis of N- acetylneuraminic acid (NeuAc), a precursor of sialic acids. Required for normal sialylation in hematopoietic cells (By similarity). Sialylation is implicated in cell adhesion, signal transduction, tumorigenicity and metastatic behavior of malignant cells. Plays an essential role in early development (753 aa)
       
  0.680
Your Current Organism:
Mus musculus
NCBI taxonomy Id: 10090
Other names: LK3 transgenic mice, M. musculus, Mus, Mus muscaris, Mus musculus, Mus sp. 129SV, house mouse, mice, mouse, nude mice, transgenic mice
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