node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
B4galnt4 | Fra10ac1 | ENSMUSP00000039758 | ENSMUSP00000070534 | N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N-acetylgalactosaminyltransferase 1; Transfers N-acetylgalactosamine (GalNAc) from UDP-GalNAc to N-acetylglucosamine-beta-benzyl with a beta-1,4-linkage to form N,N'- diacetyllactosediamine, GalNAc-beta-1,4-GlcNAc structures in N-linked glycans and probably O-linked glycans; Belongs to the chondroitin N- acetylgalactosaminyltransferase family. | Protein FRA10AC1 homolog. | 0.514 |
Ccm2l | Fra10ac1 | ENSMUSP00000105425 | ENSMUSP00000070534 | Cerebral cavernous malformations 2 protein-like. | Protein FRA10AC1 homolog. | 0.451 |
Cwc27 | Fra10ac1 | ENSMUSP00000022228 | ENSMUSP00000070534 | Spliceosome-associated protein CWC27 homolog; As part of the spliceosome, plays a role in pre-mRNA splicing. Probable inactive PPIase with no peptidyl-prolyl cis-trans isomerase activity; Belongs to the cyclophilin-type PPIase family. | Protein FRA10AC1 homolog. | 0.672 |
Dnajc7 | Fra10ac1 | ENSMUSP00000014339 | ENSMUSP00000070534 | DnaJ homolog subfamily C member 7; Acts as co-chaperone regulating the molecular chaperones HSP70 and HSP90 in folding of steroid receptors, such as the glucocorticoid receptor and the progesterone receptor. Proposed to act as a recycling chaperone by facilitating the return of chaperone substrates to early stages of chaperoning if further folding is required. In vitro, induces ATP-independent dissociation of HSP90 but not of HSP70 from the chaperone-substrate complexes (By similarity). Recruits NR1I3 to the cytoplasm. | Protein FRA10AC1 homolog. | 0.525 |
Ebag9 | Fra10ac1 | ENSMUSP00000154361 | ENSMUSP00000070534 | Receptor-binding cancer antigen expressed on SiSo cells; May participate in suppression of cell proliferation and induces apoptotic cell death through activation of interleukin-1-beta converting enzyme (ICE)-like proteases. | Protein FRA10AC1 homolog. | 0.461 |
Engase | Fra10ac1 | ENSMUSP00000117538 | ENSMUSP00000070534 | Cytosolic endo-beta-N-acetylglucosaminidase; Endoglycosidase that releases N-glycans from glycoproteins by cleaving the beta-1,4-glycosidic bond in the N,N'-diacetylchitobiose core. Involved in the processing of free oligosaccharides in the cytosol (By similarity). | Protein FRA10AC1 homolog. | 0.461 |
Ess2 | Fra10ac1 | ENSMUSP00000003621 | ENSMUSP00000070534 | Splicing factor ESS-2 homolog; May be involved in pre-mRNA splicing. | Protein FRA10AC1 homolog. | 0.510 |
Fra10ac1 | B4galnt4 | ENSMUSP00000070534 | ENSMUSP00000039758 | Protein FRA10AC1 homolog. | N-acetyl-beta-glucosaminyl-glycoprotein 4-beta-N-acetylgalactosaminyltransferase 1; Transfers N-acetylgalactosamine (GalNAc) from UDP-GalNAc to N-acetylglucosamine-beta-benzyl with a beta-1,4-linkage to form N,N'- diacetyllactosediamine, GalNAc-beta-1,4-GlcNAc structures in N-linked glycans and probably O-linked glycans; Belongs to the chondroitin N- acetylgalactosaminyltransferase family. | 0.514 |
Fra10ac1 | Ccm2l | ENSMUSP00000070534 | ENSMUSP00000105425 | Protein FRA10AC1 homolog. | Cerebral cavernous malformations 2 protein-like. | 0.451 |
Fra10ac1 | Cwc27 | ENSMUSP00000070534 | ENSMUSP00000022228 | Protein FRA10AC1 homolog. | Spliceosome-associated protein CWC27 homolog; As part of the spliceosome, plays a role in pre-mRNA splicing. Probable inactive PPIase with no peptidyl-prolyl cis-trans isomerase activity; Belongs to the cyclophilin-type PPIase family. | 0.672 |
Fra10ac1 | Dnajc7 | ENSMUSP00000070534 | ENSMUSP00000014339 | Protein FRA10AC1 homolog. | DnaJ homolog subfamily C member 7; Acts as co-chaperone regulating the molecular chaperones HSP70 and HSP90 in folding of steroid receptors, such as the glucocorticoid receptor and the progesterone receptor. Proposed to act as a recycling chaperone by facilitating the return of chaperone substrates to early stages of chaperoning if further folding is required. In vitro, induces ATP-independent dissociation of HSP90 but not of HSP70 from the chaperone-substrate complexes (By similarity). Recruits NR1I3 to the cytoplasm. | 0.525 |
Fra10ac1 | Ebag9 | ENSMUSP00000070534 | ENSMUSP00000154361 | Protein FRA10AC1 homolog. | Receptor-binding cancer antigen expressed on SiSo cells; May participate in suppression of cell proliferation and induces apoptotic cell death through activation of interleukin-1-beta converting enzyme (ICE)-like proteases. | 0.461 |
Fra10ac1 | Engase | ENSMUSP00000070534 | ENSMUSP00000117538 | Protein FRA10AC1 homolog. | Cytosolic endo-beta-N-acetylglucosaminidase; Endoglycosidase that releases N-glycans from glycoproteins by cleaving the beta-1,4-glycosidic bond in the N,N'-diacetylchitobiose core. Involved in the processing of free oligosaccharides in the cytosol (By similarity). | 0.461 |
Fra10ac1 | Ess2 | ENSMUSP00000070534 | ENSMUSP00000003621 | Protein FRA10AC1 homolog. | Splicing factor ESS-2 homolog; May be involved in pre-mRNA splicing. | 0.510 |
Fra10ac1 | Gigyf1 | ENSMUSP00000070534 | ENSMUSP00000031727 | Protein FRA10AC1 homolog. | GRB10-interacting GYF protein 1; May act cooperatively with GRB10 to regulate tyrosine kinase receptor signaling. May increase IGF1 receptor phosphorylation under IGF1 stimulation as well as phosphorylation of IRS1 and SHC1. | 0.483 |
Fra10ac1 | Wdr41 | ENSMUSP00000070534 | ENSMUSP00000124033 | Protein FRA10AC1 homolog. | WD repeat-containing protein 41; Non-catalytic component of the C9orf72-SMCR8 complex, a complex that has guanine nucleotide exchange factor (GEF) activity and regulates autophagy. The C9orf72-SMCR8 complex promotes the exchange of GDP to GTP, converting inactive GDP-bound RAB8A and RAB39B into their active GTP-bound form, thereby promoting autophagosome maturation. The C9orf72-SMCR8 complex also acts as a negative regulator of autophagy initiation by interacting with the ATG1/ULK1 kinase complex and inhibiting its protein kinase activity. | 0.473 |
Fra10ac1 | Zfp637 | ENSMUSP00000070534 | ENSMUSP00000108481 | Protein FRA10AC1 homolog. | Zinc finger protein 32; May be involved in transcriptional regulation. | 0.472 |
Gigyf1 | Fra10ac1 | ENSMUSP00000031727 | ENSMUSP00000070534 | GRB10-interacting GYF protein 1; May act cooperatively with GRB10 to regulate tyrosine kinase receptor signaling. May increase IGF1 receptor phosphorylation under IGF1 stimulation as well as phosphorylation of IRS1 and SHC1. | Protein FRA10AC1 homolog. | 0.483 |
Wdr41 | Fra10ac1 | ENSMUSP00000124033 | ENSMUSP00000070534 | WD repeat-containing protein 41; Non-catalytic component of the C9orf72-SMCR8 complex, a complex that has guanine nucleotide exchange factor (GEF) activity and regulates autophagy. The C9orf72-SMCR8 complex promotes the exchange of GDP to GTP, converting inactive GDP-bound RAB8A and RAB39B into their active GTP-bound form, thereby promoting autophagosome maturation. The C9orf72-SMCR8 complex also acts as a negative regulator of autophagy initiation by interacting with the ATG1/ULK1 kinase complex and inhibiting its protein kinase activity. | Protein FRA10AC1 homolog. | 0.473 |
Zfp637 | Fra10ac1 | ENSMUSP00000108481 | ENSMUSP00000070534 | Zinc finger protein 32; May be involved in transcriptional regulation. | Protein FRA10AC1 homolog. | 0.472 |