node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Alb | Car12 | ENSMUSP00000031314 | ENSMUSP00000071786 | Serum albumin; Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc (By similarity). Major calcium and magnesium transporter in plasma, binds approximately 45% of circulating calcium and magnesium in plasma (By similarity). Potentially has more than two calcium-binding sites and might additionally bind calcium in a non-specific manner (B [...] | Carbonic anhydrase 12; Reversible hydration of carbon dioxide; Belongs to the alpha-carbonic anhydrase family. | 0.543 |
Alb | Car14 | ENSMUSP00000031314 | ENSMUSP00000036983 | Serum albumin; Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc (By similarity). Major calcium and magnesium transporter in plasma, binds approximately 45% of circulating calcium and magnesium in plasma (By similarity). Potentially has more than two calcium-binding sites and might additionally bind calcium in a non-specific manner (B [...] | Carbonic anhydrase 14; Reversible hydration of carbon dioxide; Belongs to the alpha-carbonic anhydrase family. | 0.555 |
Alb | Car4 | ENSMUSP00000031314 | ENSMUSP00000099483 | Serum albumin; Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc (By similarity). Major calcium and magnesium transporter in plasma, binds approximately 45% of circulating calcium and magnesium in plasma (By similarity). Potentially has more than two calcium-binding sites and might additionally bind calcium in a non-specific manner (B [...] | Carbonic anhydrase 4; Reversible hydration of carbon dioxide. May stimulate the sodium/bicarbonate transporter activity of SLC4A4 (By similarity). | 0.413 |
Alb | Car9 | ENSMUSP00000031314 | ENSMUSP00000030183 | Serum albumin; Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc (By similarity). Major calcium and magnesium transporter in plasma, binds approximately 45% of circulating calcium and magnesium in plasma (By similarity). Potentially has more than two calcium-binding sites and might additionally bind calcium in a non-specific manner (B [...] | Carbonic anhydrase 9; Reversible hydration of carbon dioxide. Participates in pH regulation (By similarity). | 0.657 |
Alb | Slc9a1 | ENSMUSP00000031314 | ENSMUSP00000030669 | Serum albumin; Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc (By similarity). Major calcium and magnesium transporter in plasma, binds approximately 45% of circulating calcium and magnesium in plasma (By similarity). Potentially has more than two calcium-binding sites and might additionally bind calcium in a non-specific manner (B [...] | Sodium/hydrogen exchanger 1; Involved in pH regulation to eliminate acids generated by active metabolism or to counter adverse environmental conditions. Major proton extruding system driven by the inward sodium ion chemical gradient. Plays an important role in signal transduction. | 0.400 |
Car12 | Alb | ENSMUSP00000071786 | ENSMUSP00000031314 | Carbonic anhydrase 12; Reversible hydration of carbon dioxide; Belongs to the alpha-carbonic anhydrase family. | Serum albumin; Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc (By similarity). Major calcium and magnesium transporter in plasma, binds approximately 45% of circulating calcium and magnesium in plasma (By similarity). Potentially has more than two calcium-binding sites and might additionally bind calcium in a non-specific manner (B [...] | 0.543 |
Car12 | Car14 | ENSMUSP00000071786 | ENSMUSP00000036983 | Carbonic anhydrase 12; Reversible hydration of carbon dioxide; Belongs to the alpha-carbonic anhydrase family. | Carbonic anhydrase 14; Reversible hydration of carbon dioxide; Belongs to the alpha-carbonic anhydrase family. | 0.566 |
Car12 | Car4 | ENSMUSP00000071786 | ENSMUSP00000099483 | Carbonic anhydrase 12; Reversible hydration of carbon dioxide; Belongs to the alpha-carbonic anhydrase family. | Carbonic anhydrase 4; Reversible hydration of carbon dioxide. May stimulate the sodium/bicarbonate transporter activity of SLC4A4 (By similarity). | 0.643 |
Car12 | Car9 | ENSMUSP00000071786 | ENSMUSP00000030183 | Carbonic anhydrase 12; Reversible hydration of carbon dioxide; Belongs to the alpha-carbonic anhydrase family. | Carbonic anhydrase 9; Reversible hydration of carbon dioxide. Participates in pH regulation (By similarity). | 0.649 |
Car12 | Rpf2 | ENSMUSP00000071786 | ENSMUSP00000138581 | Carbonic anhydrase 12; Reversible hydration of carbon dioxide; Belongs to the alpha-carbonic anhydrase family. | Ribosome production factor 2 homolog; Involved in ribosomal large subunit assembly. May regulate the localization of the 5S RNP/5S ribonucleoprotein particle to the nucleolus; Belongs to the RPF2 family. | 0.568 |
Car12 | Slc16a3 | ENSMUSP00000071786 | ENSMUSP00000125846 | Carbonic anhydrase 12; Reversible hydration of carbon dioxide; Belongs to the alpha-carbonic anhydrase family. | Monocarboxylate transporter 4; Proton-linked monocarboxylate transporter. Catalyzes the rapid transport across the plasma membrane of many monocarboxylates such as lactate, pyruvate, branched-chain oxo acids derived from leucine, valine and isoleucine, and the ketone bodies acetoacetate, beta-hydroxybutyrate and acetate (By similarity); Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family. | 0.520 |
Car12 | Slc4a2 | ENSMUSP00000071786 | ENSMUSP00000078972 | Carbonic anhydrase 12; Reversible hydration of carbon dioxide; Belongs to the alpha-carbonic anhydrase family. | Anion exchange protein 2; Plasma membrane anion exchange protein of wide distribution; Belongs to the anion exchanger (TC 2.A.31) family. | 0.672 |
Car12 | Slc4a4 | ENSMUSP00000071786 | ENSMUSP00000121744 | Carbonic anhydrase 12; Reversible hydration of carbon dioxide; Belongs to the alpha-carbonic anhydrase family. | Electrogenic sodium bicarbonate cotransporter 1; Electrogenic sodium/bicarbonate cotransporter with a Na(+):HCO3(-) stoichiometry varying from 1:2 to 1:3. May regulate bicarbonate influx/efflux at the basolateral membrane of cells and regulate intracellular pH; Belongs to the anion exchanger (TC 2.A.31) family. | 0.574 |
Car12 | Slc4a7 | ENSMUSP00000071786 | ENSMUSP00000058313 | Carbonic anhydrase 12; Reversible hydration of carbon dioxide; Belongs to the alpha-carbonic anhydrase family. | Sodium bicarbonate cotransporter 3; Electroneutral sodium- and bicarbonate-dependent cotransporter with a Na(+):HCO3(-) 1:1 stoichiometry. Regulates intracellular pH and may play a role in bicarbonate salvage in secretory epithelia. May also have an associated sodium channel activity; Belongs to the anion exchanger (TC 2.A.31) family. | 0.526 |
Car12 | Slc9a1 | ENSMUSP00000071786 | ENSMUSP00000030669 | Carbonic anhydrase 12; Reversible hydration of carbon dioxide; Belongs to the alpha-carbonic anhydrase family. | Sodium/hydrogen exchanger 1; Involved in pH regulation to eliminate acids generated by active metabolism or to counter adverse environmental conditions. Major proton extruding system driven by the inward sodium ion chemical gradient. Plays an important role in signal transduction. | 0.654 |
Car14 | Alb | ENSMUSP00000036983 | ENSMUSP00000031314 | Carbonic anhydrase 14; Reversible hydration of carbon dioxide; Belongs to the alpha-carbonic anhydrase family. | Serum albumin; Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc (By similarity). Major calcium and magnesium transporter in plasma, binds approximately 45% of circulating calcium and magnesium in plasma (By similarity). Potentially has more than two calcium-binding sites and might additionally bind calcium in a non-specific manner (B [...] | 0.555 |
Car14 | Car12 | ENSMUSP00000036983 | ENSMUSP00000071786 | Carbonic anhydrase 14; Reversible hydration of carbon dioxide; Belongs to the alpha-carbonic anhydrase family. | Carbonic anhydrase 12; Reversible hydration of carbon dioxide; Belongs to the alpha-carbonic anhydrase family. | 0.566 |
Car14 | Car4 | ENSMUSP00000036983 | ENSMUSP00000099483 | Carbonic anhydrase 14; Reversible hydration of carbon dioxide; Belongs to the alpha-carbonic anhydrase family. | Carbonic anhydrase 4; Reversible hydration of carbon dioxide. May stimulate the sodium/bicarbonate transporter activity of SLC4A4 (By similarity). | 0.655 |
Car14 | Car9 | ENSMUSP00000036983 | ENSMUSP00000030183 | Carbonic anhydrase 14; Reversible hydration of carbon dioxide; Belongs to the alpha-carbonic anhydrase family. | Carbonic anhydrase 9; Reversible hydration of carbon dioxide. Participates in pH regulation (By similarity). | 0.587 |
Car14 | Rpf2 | ENSMUSP00000036983 | ENSMUSP00000138581 | Carbonic anhydrase 14; Reversible hydration of carbon dioxide; Belongs to the alpha-carbonic anhydrase family. | Ribosome production factor 2 homolog; Involved in ribosomal large subunit assembly. May regulate the localization of the 5S RNP/5S ribonucleoprotein particle to the nucleolus; Belongs to the RPF2 family. | 0.568 |