STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Csn1s2bAlpha-S2-casein-like B; Important role in the capacity of milk to transport calcium phosphate. (143 aa)    
Predicted Functional Partners:
Csn1s1
Alpha-S1-casein; Important role in the capacity of milk to transport calcium phosphate.
   
  
 0.985
Csn1s2a
Alpha-S2-casein-like A; Important role in the capacity of milk to transport calcium phosphate.
   
  
 0.891
Glycam1
Glycosylation-dependent cell adhesion molecule 1; Adhesion molecule that accomplishes cell binding by presenting carbohydrate(s) to the lectin domain of L-selectin; Belongs to the PP3/GlyCAM-1 family.
   
  
 0.855
Csn3
Kappa-casein; Kappa-casein stabilizes micelle formation, preventing casein precipitation in milk.
   
  
 0.832
Csn2
Beta-casein; Important role in determination of the surface properties of the casein micelles.
   
  
 0.789
Wap
Whey acidic protein; Could be a protease inhibitor. May play an important role in mammary gland development and tissue remodeling.
   
  
 0.739
Lalba
Alpha-lactalbumin; Regulatory subunit of lactose synthase, changes the substrate specificity of galactosyltransferase in the mammary gland making glucose a good acceptor substrate for this enzyme. This enables LS to synthesize lactose, the major carbohydrate component of milk. In other tissues, galactosyltransferase transfers galactose onto the N- acetylglucosamine of the oligosaccharide chains in glycoproteins.
   
  
 0.738
Prr27
4930432K09Rik protein.
   
  
 0.651
Bpifa2
BPI fold-containing family A member 2; Has strong antibacterial activity against P. aeruginosa. Belongs to the BPI/LBP/Plunc superfamily. Plunc family.
   
  
 0.514
Zfp839
Zinc finger protein 839.
   
  
 0.505
Your Current Organism:
Mus musculus
NCBI taxonomy Id: 10090
Other names: LK3 transgenic mice, M. musculus, Mus sp. 129SV, house mouse, mouse, nude mice, transgenic mice
Server load: low (24%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.