STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Zscan5bZinc finger and SCAN domain-containing 5B. (468 aa)    
Predicted Functional Partners:
Obox6
Oocyte-specific homeobox 6.
   
 
 0.577
Nlrp9a
NACHT, LRR and PYD domains-containing protein 9A; May be involved in inflammation; Belongs to the NLRP family.
   
  
 0.565
Khdc1b
KH homology domain-containing protein 1B; Belongs to the KHDC1 family.
   
  
 0.540
Rfpl4
Ret finger protein-like 4A.
   
 
 0.519
Khdc1a
KH homology domain-containing protein 1A; Has pro-apoptotic activity.
   
  
 0.503
Teddm1a
Transmembrane epididymal protein 1A.
      
 0.489
Rubcnl
Protein associated with UVRAG as autophagy enhancer; Regulator of autophagy that promotes autophagosome maturation by facilitating the biogenesis of phosphatidylinositol 3-phosphate (PtdIns(3)P) in late steps of autophagy. Acts by antagonizing RUBCN, thereby stimulating phosphatidylinositol 3-kinase activity of the PI3K/PI3KC3 complex (By similarity). Following anchorage to the autophagosomal SNARE STX17, promotes the recruitment of PI3K/PI3KC3 and HOPS complexes to the autophagosome to regulate the fusion specificity of autophagosomes with late endosomes/lysosomes (By similarity). Bin [...]
      
 0.477
Ubtfl1
Upstream-binding factor 1-like protein 1; Essential for proliferation of the inner cell mass and trophectodermal cells in peri-implantation development.
   
 
 0.441
Emc6
ER membrane protein complex subunit 6; Belongs to the EMC6 family.
    
 
 0.439
Gemin7
Gem-associated protein 7; The SMN complex plays a catalyst role in the assembly of small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Thereby, plays an important role in the splicing of cellular pre-mRNAs. Most spliceosomal snRNPs contain a common set of Sm proteins SNRPB, SNRPD1, SNRPD2, SNRPD3, SNRPE, SNRPF and SNRPG that assemble in a heptameric protein ring on the Sm site of the small nuclear RNA to form the core snRNP. In the cytosol, the Sm proteins SNRPD1, SNRPD2, SNRPE, SNRPF and SNRPG are trapped in an inactive 6S pICln-Sm complex by the chapero [...]
      
 0.432
Your Current Organism:
Mus musculus
NCBI taxonomy Id: 10090
Other names: LK3 transgenic mice, M. musculus, Mus sp. 129SV, house mouse, mouse, nude mice, transgenic mice
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