STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PipProlactin-inducible protein homolog. (146 aa)    
Predicted Functional Partners:
Azgp1
Zinc-alpha-2-glycoprotein; Stimulates lipid degradation in adipocytes and causes the extensive fat losses associated with some advanced cancers.
   
 0.984
Bpifa2
BPI fold-containing family A member 2; Has strong antibacterial activity against P. aeruginosa. Belongs to the BPI/LBP/Plunc superfamily. Plunc family.
   
  
 0.767
Prol1
Proline-rich, lacrimal 1.
   
  
 0.750
Dcpp1
Demilune cell and parotid protein 1.
   
  
 0.646
Dcpp3
Demilune cell and parotid protein 3.
   
  
 0.625
Mucl2
Mucin-like protein 2.
   
  
 0.619
Smr3a
Submaxillary gland androgen-regulated protein 3A; May play a role in protection or detoxification.
   
  
 0.607
Cst10
Cystatin 10; May play a role in the last steps of the chondrocyte differentiation pathway as an inducer of maturation. Induces chondrocyte calcification during endochondral ossification by playing a role in the transcriptional inhibition of ENPP1, a generator of pyrophosphate which inhibits calcification. Possibly impairs the binding of a transcription factor to the ENPP1 promoter. Unlike other cystatins, does not have thiol protease inhibitor activity.
   
  
 0.607
Krt7
Keratin, type II cytoskeletal 7; Blocks interferon-dependent interphase and stimulates DNA synthesis in cells.
    
 
 0.603
Armh4
Armadillo-like helical domain-containing protein 4.
      
 0.593
Your Current Organism:
Mus musculus
NCBI taxonomy Id: 10090
Other names: LK3 transgenic mice, M. musculus, Mus sp. 129SV, house mouse, mouse, nude mice, transgenic mice
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