node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Bms1 | Dcaf13 | ENSMUSP00000032237 | ENSMUSP00000022909 | BMS1 homolog, ribosome assembly protein (Yeast). | DDB1- and CUL4-associated factor 13; Possible role in ribosomal RNA processing. May function as a substrate receptor for CUL4-DDB1 E3 ubiquitin-protein ligase complex (By similarity); Belongs to the WD repeat DCAF13/WDSOF1 family. | 0.995 |
Bms1 | Glmn | ENSMUSP00000032237 | ENSMUSP00000077168 | BMS1 homolog, ribosome assembly protein (Yeast). | Glomulin; Regulatory component of cullin-RING-based SCF (SKP1-Cullin-F- box protein) E3 ubiquitin-protein ligase complexes. Inhibits E3 ubiquitin ligase activity by binding to the RING domain of RBX1 and inhibiting its interaction with the E2 ubiquitin-conjugating enzyme CDC34. Inhibits RBX1-mediated neddylation of CUL1 (By similarity). Required for normal stability and normal cellular levels of key components of SCF ubiquitin ligase complexes, including FBXW7, RBX1, CUL1, CUL2, CUL3, CUL4A, and thereby contributes to the regulation of CCNE1 and MYC levels. Essential for normal develop [...] | 0.945 |
Bms1 | Heatr1 | ENSMUSP00000032237 | ENSMUSP00000054084 | BMS1 homolog, ribosome assembly protein (Yeast). | HEAT repeat-containing 1. | 0.999 |
Bms1 | Nat10 | ENSMUSP00000032237 | ENSMUSP00000028608 | BMS1 homolog, ribosome assembly protein (Yeast). | RNA cytidine acetyltransferase; RNA cytidine acetyltransferase that catalyzes the formation of N(4)-acetylcytidine (ac4C) modification on mRNAs, 18S rRNA and tRNAs. Catalyzes ac4C modification of a broad range of mRNAs, enhancing mRNA stability and translation. mRNA ac4C modification is frequently present within wobble cytidine sites and promotes translation efficiency. Mediates the formation of ac4C at position 1842 in 18S rRNA (By similarity). May also catalyze the formation of ac4C at position 1337 in 18S rRNA (By similarity). Required for early nucleolar cleavages of precursor rRNA [...] | 0.999 |
Bms1 | Nop14 | ENSMUSP00000032237 | ENSMUSP00000038382 | BMS1 homolog, ribosome assembly protein (Yeast). | Nucleolar protein 14; Involved in nucleolar processing of pre-18S ribosomal RNA. Has a role in the nuclear export of 40S pre-ribosomal subunit to the cytoplasm (By similarity). | 0.999 |
Bms1 | Pdcd11 | ENSMUSP00000032237 | ENSMUSP00000072008 | BMS1 homolog, ribosome assembly protein (Yeast). | Protein RRP5 homolog; Essential for the generation of mature 18S rRNA, specifically necessary for cleavages at sites A0, 1 and 2 of the 47S precursor. Directly interacts with U3 snoRNA (By similarity). | 0.999 |
Bms1 | Pwp2 | ENSMUSP00000032237 | ENSMUSP00000045812 | BMS1 homolog, ribosome assembly protein (Yeast). | Periodic tryptophan protein 2 homolog. | 0.999 |
Bms1 | Tbl3 | ENSMUSP00000032237 | ENSMUSP00000120911 | BMS1 homolog, ribosome assembly protein (Yeast). | Transducin beta-like protein 3. | 0.999 |
Bms1 | Wdr36 | ENSMUSP00000032237 | ENSMUSP00000052465 | BMS1 homolog, ribosome assembly protein (Yeast). | WD repeat domain 36. | 0.999 |
Bms1 | Wdr75 | ENSMUSP00000032237 | ENSMUSP00000027139 | BMS1 homolog, ribosome assembly protein (Yeast). | WD repeat-containing protein 75; Ribosome biogenesis factor. Involved in nucleolar processing of pre-18S ribosomal RNA. Required for optimal pre-ribosomal RNA transcription by RNA polymerase I. | 0.999 |
Dcaf13 | Bms1 | ENSMUSP00000022909 | ENSMUSP00000032237 | DDB1- and CUL4-associated factor 13; Possible role in ribosomal RNA processing. May function as a substrate receptor for CUL4-DDB1 E3 ubiquitin-protein ligase complex (By similarity); Belongs to the WD repeat DCAF13/WDSOF1 family. | BMS1 homolog, ribosome assembly protein (Yeast). | 0.995 |
Dcaf13 | Glmn | ENSMUSP00000022909 | ENSMUSP00000077168 | DDB1- and CUL4-associated factor 13; Possible role in ribosomal RNA processing. May function as a substrate receptor for CUL4-DDB1 E3 ubiquitin-protein ligase complex (By similarity); Belongs to the WD repeat DCAF13/WDSOF1 family. | Glomulin; Regulatory component of cullin-RING-based SCF (SKP1-Cullin-F- box protein) E3 ubiquitin-protein ligase complexes. Inhibits E3 ubiquitin ligase activity by binding to the RING domain of RBX1 and inhibiting its interaction with the E2 ubiquitin-conjugating enzyme CDC34. Inhibits RBX1-mediated neddylation of CUL1 (By similarity). Required for normal stability and normal cellular levels of key components of SCF ubiquitin ligase complexes, including FBXW7, RBX1, CUL1, CUL2, CUL3, CUL4A, and thereby contributes to the regulation of CCNE1 and MYC levels. Essential for normal develop [...] | 0.956 |
Dcaf13 | Heatr1 | ENSMUSP00000022909 | ENSMUSP00000054084 | DDB1- and CUL4-associated factor 13; Possible role in ribosomal RNA processing. May function as a substrate receptor for CUL4-DDB1 E3 ubiquitin-protein ligase complex (By similarity); Belongs to the WD repeat DCAF13/WDSOF1 family. | HEAT repeat-containing 1. | 0.992 |
Dcaf13 | Nat10 | ENSMUSP00000022909 | ENSMUSP00000028608 | DDB1- and CUL4-associated factor 13; Possible role in ribosomal RNA processing. May function as a substrate receptor for CUL4-DDB1 E3 ubiquitin-protein ligase complex (By similarity); Belongs to the WD repeat DCAF13/WDSOF1 family. | RNA cytidine acetyltransferase; RNA cytidine acetyltransferase that catalyzes the formation of N(4)-acetylcytidine (ac4C) modification on mRNAs, 18S rRNA and tRNAs. Catalyzes ac4C modification of a broad range of mRNAs, enhancing mRNA stability and translation. mRNA ac4C modification is frequently present within wobble cytidine sites and promotes translation efficiency. Mediates the formation of ac4C at position 1842 in 18S rRNA (By similarity). May also catalyze the formation of ac4C at position 1337 in 18S rRNA (By similarity). Required for early nucleolar cleavages of precursor rRNA [...] | 0.972 |
Dcaf13 | Nop14 | ENSMUSP00000022909 | ENSMUSP00000038382 | DDB1- and CUL4-associated factor 13; Possible role in ribosomal RNA processing. May function as a substrate receptor for CUL4-DDB1 E3 ubiquitin-protein ligase complex (By similarity); Belongs to the WD repeat DCAF13/WDSOF1 family. | Nucleolar protein 14; Involved in nucleolar processing of pre-18S ribosomal RNA. Has a role in the nuclear export of 40S pre-ribosomal subunit to the cytoplasm (By similarity). | 0.993 |
Dcaf13 | Pdcd11 | ENSMUSP00000022909 | ENSMUSP00000072008 | DDB1- and CUL4-associated factor 13; Possible role in ribosomal RNA processing. May function as a substrate receptor for CUL4-DDB1 E3 ubiquitin-protein ligase complex (By similarity); Belongs to the WD repeat DCAF13/WDSOF1 family. | Protein RRP5 homolog; Essential for the generation of mature 18S rRNA, specifically necessary for cleavages at sites A0, 1 and 2 of the 47S precursor. Directly interacts with U3 snoRNA (By similarity). | 0.988 |
Dcaf13 | Pwp2 | ENSMUSP00000022909 | ENSMUSP00000045812 | DDB1- and CUL4-associated factor 13; Possible role in ribosomal RNA processing. May function as a substrate receptor for CUL4-DDB1 E3 ubiquitin-protein ligase complex (By similarity); Belongs to the WD repeat DCAF13/WDSOF1 family. | Periodic tryptophan protein 2 homolog. | 0.997 |
Dcaf13 | Tbl3 | ENSMUSP00000022909 | ENSMUSP00000120911 | DDB1- and CUL4-associated factor 13; Possible role in ribosomal RNA processing. May function as a substrate receptor for CUL4-DDB1 E3 ubiquitin-protein ligase complex (By similarity); Belongs to the WD repeat DCAF13/WDSOF1 family. | Transducin beta-like protein 3. | 0.997 |
Dcaf13 | Wdr36 | ENSMUSP00000022909 | ENSMUSP00000052465 | DDB1- and CUL4-associated factor 13; Possible role in ribosomal RNA processing. May function as a substrate receptor for CUL4-DDB1 E3 ubiquitin-protein ligase complex (By similarity); Belongs to the WD repeat DCAF13/WDSOF1 family. | WD repeat domain 36. | 0.998 |
Dcaf13 | Wdr75 | ENSMUSP00000022909 | ENSMUSP00000027139 | DDB1- and CUL4-associated factor 13; Possible role in ribosomal RNA processing. May function as a substrate receptor for CUL4-DDB1 E3 ubiquitin-protein ligase complex (By similarity); Belongs to the WD repeat DCAF13/WDSOF1 family. | WD repeat-containing protein 75; Ribosome biogenesis factor. Involved in nucleolar processing of pre-18S ribosomal RNA. Required for optimal pre-ribosomal RNA transcription by RNA polymerase I. | 0.994 |