STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Nrsn2Neurensin-2; May play a role in maintenance and/or transport of vesicles. Belongs to the VMP family. (202 aa)    
Predicted Functional Partners:
Nxph4
Neurexophilin; May be signaling molecules that resemble neuropeptides.
   
  
 0.632
Sncb
Beta-synuclein; May be involved in neuronal plasticity.
   
  
 0.599
Hmgxb3
HMG box domain-containing 3.
      
 0.529
Fam174a
Membrane protein FAM174A.
      
 0.503
Chd9
Chromodomain-helicase-DNA-binding protein 9; Acts as a transcriptional coactivator for PPARA and possibly other nuclear receptors. Proposed to be a ATP-dependent chromatin remodeling protein. Has DNA-dependent ATPase activity and binds to A/T- rich DNA (By similarity). Associates with A/T-rich regulatory regions in promoters of genes that participate in the differentiation of progenitors during osteogenesis; Belongs to the SNF2/RAD54 helicase family.
      
 0.461
Lyplal1
Lysophospholipase-like protein 1; Has depalmitoylating activity toward KCNMA1. Does not exhibit phospholipase nor triacylglycerol lipase activity, able to hydrolyze only short chain substrates due to its shallow active site (By similarity).
      
 0.460
Necap2
Adaptin ear-binding coat-associated protein 2; Involved in endocytosis.
      
 0.453
Rrp15
RRP15-like protein.
      
 0.446
Camk1g
Calcium/calmodulin-dependent protein kinase type 1G; Calcium/calmodulin-dependent protein kinase belonging to a proposed calcium-triggered signaling cascade. In vitro phosphorylates transcription factor CREB1.
   
  
 0.441
Fstl5
Follistatin-related protein 5.
   
  
 0.427
Your Current Organism:
Mus musculus
NCBI taxonomy Id: 10090
Other names: LK3 transgenic mice, M. musculus, Mus sp. 129SV, house mouse, mouse, nude mice, transgenic mice
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