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S100a7a protein (mouse) - STRING interaction network
"S100a7a" - S100 calcium binding protein A7A in Mus musculus
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Edges represent protein-protein associations
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
S100a7aS100 calcium binding protein A7A; Belongs to the S-100 family (108 aa)    
Predicted Functional Partners:
S100a1
Protein S100-A1; Probably acts as a Ca(2+) signal transducer. In response to an increase in intracellular Ca(2+) levels, binds calcium which triggers a conformational change. This conformational change allows interaction of S1001A with specific target proteins, such as TPR-containing proteins, and the modulation of their activity (94 aa)
           
  0.590
S100a2
S100 calcium binding protein A2 (104 aa)
           
  0.586
Tchhl1
Trichohyalin-like 1; Belongs to the S-100 family (638 aa)
     
   
  0.579
S100a11
Protein S100-A11; Facilitates the differentiation and the cornification of keratinocytes (98 aa)
           
  0.535
S100a13
Protein S100-A13; Plays a role in the export of proteins that lack a signal peptide and are secreted by an alternative pathway. Binds two calcium ions per subunit. Binds one copper ion. Binding of one copper ion does not interfere with calcium binding. Required for the copper-dependent stress-induced export of IL1A and FGF1. The calcium-free protein binds to lipid vesicles containing phosphatidylserine, but not to vesicles containing phosphatidylcholine (160 aa)
           
  0.520
Defb14
Beta-defensin 14; Has antibacterial activity (67 aa)
           
  0.494
Rptn
Repetin; Involved in the cornified cell envelope formation. Multifunctional epidermal matrix protein; Belongs to the S100-fused protein family (1118 aa)
           
  0.493
S100b
Protein S100-B; Weakly binds calcium but binds zinc very tightly- distinct binding sites with different affinities exist for both ions on each monomer. Physiological concentrations of potassium ion antagonize the binding of both divalent cations, especially affecting high-affinity calcium-binding sites. Binds to and initiates the activation of STK38 by releasing autoinhibitory intramolecular interactions within the kinase. Interaction with AGER after myocardial infarction may play a role in myocyte apoptosis by activating ERK1/2 and p53/TP53 signaling. Could assist ATAD3A cytoplasmic p [...] (92 aa)
           
  0.483
S100a3
Protein S100-A3; Binds both calcium and zinc. May be involved in calcium- dependent cuticle cell differentiation, hair shaft and hair cuticular barrier formation (By similarity) (101 aa)
           
  0.483
Hrnr
Hornerin; Component of the epidermal cornified cell envelopes; Belongs to the S100-fused protein family (3234 aa)
           
  0.457
Your Current Organism:
Mus musculus
NCBI taxonomy Id: 10090
Other names: LK3 transgenic mice, M. musculus, Mus muscaris, Mus musculus, Mus sp. 129SV, house mouse, mouse, nude mice, transgenic mice
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