node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Cherp | Ddx46 | ENSMUSP00000148273 | ENSMUSP00000133245 | Calcium homeostasis endoplasmic reticulum protein; Involved in calcium homeostasis, growth and proliferation. | Probable ATP-dependent RNA helicase DDX46; Plays an essential role in splicing, either prior to, or during A complex formation. | 0.852 |
Cherp | Dhx15 | ENSMUSP00000148273 | ENSMUSP00000031061 | Calcium homeostasis endoplasmic reticulum protein; Involved in calcium homeostasis, growth and proliferation. | Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX15; Pre-mRNA processing factor involved in disassembly of spliceosomes after the release of mature mRNA. In cooperation with TFIP11 seem to be involved in the transition of the U2, U5 and U6 snRNP-containing IL complex to the snRNP-free IS complex leading to efficient debranching and turnover of excised introns (By similarity). Belongs to the DEAD box helicase family. DEAH subfamily. DDX15/PRP43 sub-subfamily. | 0.923 |
Cherp | Phf5a | ENSMUSP00000148273 | ENSMUSP00000023117 | Calcium homeostasis endoplasmic reticulum protein; Involved in calcium homeostasis, growth and proliferation. | PHD finger-like domain-containing protein 5A; Involved with the PAF1 complex (PAF1C) in transcriptional elongation by RNA polymerase II, and in regulation of development and maintenance of embryonic stem cell (ESC) pluripotency. Required for maintenance of ESCs self-renewal and cellular reprogramming of stem cells. Maintains pluripotency by recruiting and stabilizing PAF1C on pluripotency genes loci, and by regulating the expression of the pluripotency genes. Regulates the deposition of elongation-associated histone modifications, including dimethylated histone H3 'Lys-79' (H3K79me2) a [...] | 0.899 |
Cherp | Puf60 | ENSMUSP00000148273 | ENSMUSP00000098096 | Calcium homeostasis endoplasmic reticulum protein; Involved in calcium homeostasis, growth and proliferation. | Poly(U)-binding-splicing factor PUF60; DNA- and RNA-binding protein, involved in several nuclear processes such as pre-mRNA splicing, apoptosis and transcription regulation. In association with FUBP1 regulates MYC transcription at the P2 promoter through the core-TFIIH basal transcription factor. Acts as a transcriptional repressor through the core-TFIIH basal transcription factor. Represses FUBP1-induced transcriptional activation but not basal transcription. Decreases ERCC3 helicase activity. Is also involved in pre-mRNA splicing. Promotes splicing of an intron with weak 3'-splice si [...] | 0.880 |
Cherp | Raver1 | ENSMUSP00000148273 | ENSMUSP00000111150 | Calcium homeostasis endoplasmic reticulum protein; Involved in calcium homeostasis, growth and proliferation. | Ribonucleoprotein PTB-binding 1; Cooperates with PTBP1 to modulate regulated alternative splicing events. Promotes exon skipping. Cooperates with PTBP1 to modulate switching between mutually exclusive exons during maturation of the TPM1 pre-mRNA. | 0.856 |
Cherp | Rbm17 | ENSMUSP00000148273 | ENSMUSP00000041831 | Calcium homeostasis endoplasmic reticulum protein; Involved in calcium homeostasis, growth and proliferation. | Splicing factor 45; Splice factor that binds to the single-stranded 3'AG at the exon/intron border and promotes its utilization in the second catalytic step. Involved in the regulation of alternative splicing and the utilization of cryptic splice sites (By similarity). | 0.981 |
Cherp | Sf3a2 | ENSMUSP00000148273 | ENSMUSP00000117160 | Calcium homeostasis endoplasmic reticulum protein; Involved in calcium homeostasis, growth and proliferation. | Splicing factor 3A subunit 2; Involved in pre-mRNA splicing as a component of the splicing factor SF3A complex that contributes to the assembly of the 17S U2 snRNP, and the subsequent assembly of the pre-spliceosome 'E' complex and the pre-catalytic spliceosome 'A' complex. Involved in pre-mRNA splicing as a component of pre-catalytic spliceosome 'B' complexes, including the Bact complex. Interacts directly with the duplex formed by U2 snRNA and the intron; Belongs to the SF3A2 family. | 0.910 |
Cherp | Smndc1 | ENSMUSP00000148273 | ENSMUSP00000025997 | Calcium homeostasis endoplasmic reticulum protein; Involved in calcium homeostasis, growth and proliferation. | Survival of motor neuron-related-splicing factor 30; Necessary for spliceosome assembly. Overexpression causes apoptosis (By similarity); Belongs to the SMN family. | 0.815 |
Cherp | Snrpa1 | ENSMUSP00000148273 | ENSMUSP00000117947 | Calcium homeostasis endoplasmic reticulum protein; Involved in calcium homeostasis, growth and proliferation. | U2 small nuclear ribonucleoprotein A; Involved in pre-mRNA splicing as component of the spliceosome. Associated with sn-RNP U2, where it contributes to the binding of stem loop IV of U2 snRNA. | 0.828 |
Cherp | U2surp | ENSMUSP00000148273 | ENSMUSP00000078602 | Calcium homeostasis endoplasmic reticulum protein; Involved in calcium homeostasis, growth and proliferation. | U2 snRNP-associated SURP motif-containing protein. | 0.978 |
Ddx46 | Cherp | ENSMUSP00000133245 | ENSMUSP00000148273 | Probable ATP-dependent RNA helicase DDX46; Plays an essential role in splicing, either prior to, or during A complex formation. | Calcium homeostasis endoplasmic reticulum protein; Involved in calcium homeostasis, growth and proliferation. | 0.852 |
Ddx46 | Dhx15 | ENSMUSP00000133245 | ENSMUSP00000031061 | Probable ATP-dependent RNA helicase DDX46; Plays an essential role in splicing, either prior to, or during A complex formation. | Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX15; Pre-mRNA processing factor involved in disassembly of spliceosomes after the release of mature mRNA. In cooperation with TFIP11 seem to be involved in the transition of the U2, U5 and U6 snRNP-containing IL complex to the snRNP-free IS complex leading to efficient debranching and turnover of excised introns (By similarity). Belongs to the DEAD box helicase family. DEAH subfamily. DDX15/PRP43 sub-subfamily. | 0.946 |
Ddx46 | Phf5a | ENSMUSP00000133245 | ENSMUSP00000023117 | Probable ATP-dependent RNA helicase DDX46; Plays an essential role in splicing, either prior to, or during A complex formation. | PHD finger-like domain-containing protein 5A; Involved with the PAF1 complex (PAF1C) in transcriptional elongation by RNA polymerase II, and in regulation of development and maintenance of embryonic stem cell (ESC) pluripotency. Required for maintenance of ESCs self-renewal and cellular reprogramming of stem cells. Maintains pluripotency by recruiting and stabilizing PAF1C on pluripotency genes loci, and by regulating the expression of the pluripotency genes. Regulates the deposition of elongation-associated histone modifications, including dimethylated histone H3 'Lys-79' (H3K79me2) a [...] | 0.985 |
Ddx46 | Puf60 | ENSMUSP00000133245 | ENSMUSP00000098096 | Probable ATP-dependent RNA helicase DDX46; Plays an essential role in splicing, either prior to, or during A complex formation. | Poly(U)-binding-splicing factor PUF60; DNA- and RNA-binding protein, involved in several nuclear processes such as pre-mRNA splicing, apoptosis and transcription regulation. In association with FUBP1 regulates MYC transcription at the P2 promoter through the core-TFIIH basal transcription factor. Acts as a transcriptional repressor through the core-TFIIH basal transcription factor. Represses FUBP1-induced transcriptional activation but not basal transcription. Decreases ERCC3 helicase activity. Is also involved in pre-mRNA splicing. Promotes splicing of an intron with weak 3'-splice si [...] | 0.815 |
Ddx46 | Rbm17 | ENSMUSP00000133245 | ENSMUSP00000041831 | Probable ATP-dependent RNA helicase DDX46; Plays an essential role in splicing, either prior to, or during A complex formation. | Splicing factor 45; Splice factor that binds to the single-stranded 3'AG at the exon/intron border and promotes its utilization in the second catalytic step. Involved in the regulation of alternative splicing and the utilization of cryptic splice sites (By similarity). | 0.896 |
Ddx46 | Sf3a2 | ENSMUSP00000133245 | ENSMUSP00000117160 | Probable ATP-dependent RNA helicase DDX46; Plays an essential role in splicing, either prior to, or during A complex formation. | Splicing factor 3A subunit 2; Involved in pre-mRNA splicing as a component of the splicing factor SF3A complex that contributes to the assembly of the 17S U2 snRNP, and the subsequent assembly of the pre-spliceosome 'E' complex and the pre-catalytic spliceosome 'A' complex. Involved in pre-mRNA splicing as a component of pre-catalytic spliceosome 'B' complexes, including the Bact complex. Interacts directly with the duplex formed by U2 snRNA and the intron; Belongs to the SF3A2 family. | 0.995 |
Ddx46 | Smndc1 | ENSMUSP00000133245 | ENSMUSP00000025997 | Probable ATP-dependent RNA helicase DDX46; Plays an essential role in splicing, either prior to, or during A complex formation. | Survival of motor neuron-related-splicing factor 30; Necessary for spliceosome assembly. Overexpression causes apoptosis (By similarity); Belongs to the SMN family. | 0.881 |
Ddx46 | Snrpa1 | ENSMUSP00000133245 | ENSMUSP00000117947 | Probable ATP-dependent RNA helicase DDX46; Plays an essential role in splicing, either prior to, or during A complex formation. | U2 small nuclear ribonucleoprotein A; Involved in pre-mRNA splicing as component of the spliceosome. Associated with sn-RNP U2, where it contributes to the binding of stem loop IV of U2 snRNA. | 0.975 |
Ddx46 | U2surp | ENSMUSP00000133245 | ENSMUSP00000078602 | Probable ATP-dependent RNA helicase DDX46; Plays an essential role in splicing, either prior to, or during A complex formation. | U2 snRNP-associated SURP motif-containing protein. | 0.916 |
Dhx15 | Cherp | ENSMUSP00000031061 | ENSMUSP00000148273 | Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX15; Pre-mRNA processing factor involved in disassembly of spliceosomes after the release of mature mRNA. In cooperation with TFIP11 seem to be involved in the transition of the U2, U5 and U6 snRNP-containing IL complex to the snRNP-free IS complex leading to efficient debranching and turnover of excised introns (By similarity). Belongs to the DEAD box helicase family. DEAH subfamily. DDX15/PRP43 sub-subfamily. | Calcium homeostasis endoplasmic reticulum protein; Involved in calcium homeostasis, growth and proliferation. | 0.923 |