STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Zfp947Predicted gene, EG210853. (437 aa)    
Predicted Functional Partners:
4930579G24Rik
Uncharacterized protein C4orf46 homolog.
   
  
 0.611
1700066M21Rik
UPF0565 protein C2orf69 homolog.
   
  
 0.607
5031439G07Rik
Uncharacterized protein KIAA0930 homolog.
      
 0.574
Prelid3a
PRELI domain containing protein 3A; In vitro, the TRIAP1:PRELID3A complex mediates the transfer of phosphatidic acid (PA) between liposomes and probably functions as a PA transporter across the mitochondrion intermembrane space. Phosphatidic acid import is required for cardiolipin (CL) synthesis in the mitochondrial inner membrane.
      
 0.524
Prxl2c
Peroxiredoxin-like 2C; May regulate positively ERK1/2 signaling and AKT1 activation leading to HIF1A up-regulation with an increased expression of glycolysis genes and enhanced glycolysis.
      
 0.520
Mosmo
Modulator of smoothened protein; Acts as a negative regulator of hedgehog signaling probably by promoting internalization and subsequent degradation of smoothened protein (SMO) present in the ciliary membrane. Plays a role in sonic hedgehog (SHH)-induced spinal neural progenitor cells differentiation.
      
 0.511
Fam161a
Protein FAM161A; Involved in ciliogenesis.
      
 0.511
Mzt1
Mitotic-spindle organizing protein 1; Required for gamma-tubulin complex recruitment to the centrosome.
   
 
 0.487
Prps1l1
Phosphoribosyl pyrophosphate synthetase 1-like 1.
      
 0.459
Cyp20a1
Cytochrome P450 20A1; Belongs to the cytochrome P450 family.
   
 
 0.443
Your Current Organism:
Mus musculus
NCBI taxonomy Id: 10090
Other names: LK3 transgenic mice, M. musculus, Mus sp. 129SV, house mouse, mouse, nude mice, transgenic mice
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