Export your current network:
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of protiens in your network
Browse interactions in tabular form:
| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Ap2m1 | Dhx57 | ENSMUSP00000007216 | ENSMUSP00000083742 | AP-2 complex subunit mu; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold but i [...] | Putative ATP-dependent RNA helicase DHX57; Probable ATP-binding RNA helicase. | 0.555 |
| Cwc25 | Dhx57 | ENSMUSP00000018685 | ENSMUSP00000083742 | Pre-mRNA-splicing factor CWC25 homolog; Involved in pre-mRNA splicing as component of the spliceosome; Belongs to the CWC25 family. | Putative ATP-dependent RNA helicase DHX57; Probable ATP-binding RNA helicase. | 0.507 |
| Cwc25 | Prpf8 | ENSMUSP00000018685 | ENSMUSP00000018449 | Pre-mRNA-splicing factor CWC25 homolog; Involved in pre-mRNA splicing as component of the spliceosome; Belongs to the CWC25 family. | Pre-mRNA-processing-splicing factor 8; Plays role in pre-mRNA splicing as core component of precatalytic, catalytic and postcatalytic spliceosomal complexes, both of the predominant U2-type spliceosome and the minor U12-type spliceosome. Functions as a scaffold that mediates the ordered assembly of spliceosomal proteins and snRNAs. Required for the assembly of the U4/U6-U5 tri-snRNP complex, a building block of the spliceosome. Functions as scaffold that positions spliceosomal U2, U5 and U6 snRNAs at splice sites on pre-mRNA substrates, so that splicing can occur. Interacts with both t [...] | 0.988 |
| Cwc25 | Tfip11 | ENSMUSP00000018685 | ENSMUSP00000031288 | Pre-mRNA-splicing factor CWC25 homolog; Involved in pre-mRNA splicing as component of the spliceosome; Belongs to the CWC25 family. | Tuftelin-interacting protein 11; Involved in pre-mRNA splicing, specifically in spliceosome disassembly during late-stage splicing events. Intron turnover seems to proceed through reactions in two lariat-intron associated complexes termed Intron Large (IL) and Intron Small (IS). In cooperation with DHX15 seems to mediate the transition of the U2, U5 and U6 snRNP- containing IL complex to the snRNP-free IS complex leading to efficient debranching and turnover of excised introns. May play a role in the differentiation of ameloblasts and odontoblasts or in the forming of the enamel extrac [...] | 0.524 |
| Dhx57 | Ap2m1 | ENSMUSP00000083742 | ENSMUSP00000007216 | Putative ATP-dependent RNA helicase DHX57; Probable ATP-binding RNA helicase. | AP-2 complex subunit mu; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold but i [...] | 0.555 |
| Dhx57 | Cwc25 | ENSMUSP00000083742 | ENSMUSP00000018685 | Putative ATP-dependent RNA helicase DHX57; Probable ATP-binding RNA helicase. | Pre-mRNA-splicing factor CWC25 homolog; Involved in pre-mRNA splicing as component of the spliceosome; Belongs to the CWC25 family. | 0.507 |
| Dhx57 | Dus3l | ENSMUSP00000083742 | ENSMUSP00000007747 | Putative ATP-dependent RNA helicase DHX57; Probable ATP-binding RNA helicase. | tRNA-dihydrouridine(47) synthase [NAD(P)(+)]-like; Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs. | 0.520 |
| Dhx57 | Mlst8 | ENSMUSP00000083742 | ENSMUSP00000157137 | Putative ATP-dependent RNA helicase DHX57; Probable ATP-binding RNA helicase. | Target of rapamycin complex subunit LST8; Subunit of both mTORC1 and mTORC2, which regulates cell growth and survival in response to nutrient and hormonal signals. mTORC1 is activated in response to growth factors or amino acids. Growth factor-stimulated mTORC1 activation involves a AKT1-mediated phosphorylation of TSC1-TSC2, which leads to the activation of the RHEB GTPase that potently activates the protein kinase activity of mTORC1. Amino acid-signaling to mTORC1 requires its relocalization to the lysosomes mediated by the Ragulator complex and the Rag GTPases. Activated mTORC1 up-r [...] | 0.663 |
| Dhx57 | Nudcd3 | ENSMUSP00000083742 | ENSMUSP00000064668 | Putative ATP-dependent RNA helicase DHX57; Probable ATP-binding RNA helicase. | NudC domain-containing protein 3. | 0.558 |
| Dhx57 | Prpf8 | ENSMUSP00000083742 | ENSMUSP00000018449 | Putative ATP-dependent RNA helicase DHX57; Probable ATP-binding RNA helicase. | Pre-mRNA-processing-splicing factor 8; Plays role in pre-mRNA splicing as core component of precatalytic, catalytic and postcatalytic spliceosomal complexes, both of the predominant U2-type spliceosome and the minor U12-type spliceosome. Functions as a scaffold that mediates the ordered assembly of spliceosomal proteins and snRNAs. Required for the assembly of the U4/U6-U5 tri-snRNP complex, a building block of the spliceosome. Functions as scaffold that positions spliceosomal U2, U5 and U6 snRNAs at splice sites on pre-mRNA substrates, so that splicing can occur. Interacts with both t [...] | 0.502 |
| Dhx57 | Snx29 | ENSMUSP00000083742 | ENSMUSP00000138025 | Putative ATP-dependent RNA helicase DHX57; Probable ATP-binding RNA helicase. | Sorting nexin-29. | 0.564 |
| Dhx57 | Stxbp4 | ENSMUSP00000083742 | ENSMUSP00000116191 | Putative ATP-dependent RNA helicase DHX57; Probable ATP-binding RNA helicase. | Syntaxin-binding protein 4; Plays a role in the translocation of transport vesicles from the cytoplasm to the plasma membrane. Inhibits the translocation of SLC2A4 from intracellular vesicles to the plasma membrane by STX4A binding and preventing the interaction between STX4A and VAMP2. Stimulation with insulin disrupts the interaction with STX4A, leading to increased levels of SLC2A4 at the plasma membrane. May also play a role in the regulation of insulin release by pancreatic beta cells after stimulation by glucose. | 0.535 |
| Dhx57 | Tfip11 | ENSMUSP00000083742 | ENSMUSP00000031288 | Putative ATP-dependent RNA helicase DHX57; Probable ATP-binding RNA helicase. | Tuftelin-interacting protein 11; Involved in pre-mRNA splicing, specifically in spliceosome disassembly during late-stage splicing events. Intron turnover seems to proceed through reactions in two lariat-intron associated complexes termed Intron Large (IL) and Intron Small (IS). In cooperation with DHX15 seems to mediate the transition of the U2, U5 and U6 snRNP- containing IL complex to the snRNP-free IS complex leading to efficient debranching and turnover of excised introns. May play a role in the differentiation of ameloblasts and odontoblasts or in the forming of the enamel extrac [...] | 0.615 |
| Dhx57 | Utp18 | ENSMUSP00000083742 | ENSMUSP00000068103 | Putative ATP-dependent RNA helicase DHX57; Probable ATP-binding RNA helicase. | U3 small nucleolar RNA-associated protein 18 homolog; Involved in nucleolar processing of pre-18S ribosomal RNA. Belongs to the WD repeat UTP18 family. | 0.495 |
| Dus3l | Dhx57 | ENSMUSP00000007747 | ENSMUSP00000083742 | tRNA-dihydrouridine(47) synthase [NAD(P)(+)]-like; Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs. | Putative ATP-dependent RNA helicase DHX57; Probable ATP-binding RNA helicase. | 0.520 |
| Mlst8 | Dhx57 | ENSMUSP00000157137 | ENSMUSP00000083742 | Target of rapamycin complex subunit LST8; Subunit of both mTORC1 and mTORC2, which regulates cell growth and survival in response to nutrient and hormonal signals. mTORC1 is activated in response to growth factors or amino acids. Growth factor-stimulated mTORC1 activation involves a AKT1-mediated phosphorylation of TSC1-TSC2, which leads to the activation of the RHEB GTPase that potently activates the protein kinase activity of mTORC1. Amino acid-signaling to mTORC1 requires its relocalization to the lysosomes mediated by the Ragulator complex and the Rag GTPases. Activated mTORC1 up-r [...] | Putative ATP-dependent RNA helicase DHX57; Probable ATP-binding RNA helicase. | 0.663 |
| Nudcd3 | Dhx57 | ENSMUSP00000064668 | ENSMUSP00000083742 | NudC domain-containing protein 3. | Putative ATP-dependent RNA helicase DHX57; Probable ATP-binding RNA helicase. | 0.558 |
| Nudcd3 | Snx29 | ENSMUSP00000064668 | ENSMUSP00000138025 | NudC domain-containing protein 3. | Sorting nexin-29. | 0.463 |
| Nudcd3 | Tfip11 | ENSMUSP00000064668 | ENSMUSP00000031288 | NudC domain-containing protein 3. | Tuftelin-interacting protein 11; Involved in pre-mRNA splicing, specifically in spliceosome disassembly during late-stage splicing events. Intron turnover seems to proceed through reactions in two lariat-intron associated complexes termed Intron Large (IL) and Intron Small (IS). In cooperation with DHX15 seems to mediate the transition of the U2, U5 and U6 snRNP- containing IL complex to the snRNP-free IS complex leading to efficient debranching and turnover of excised introns. May play a role in the differentiation of ameloblasts and odontoblasts or in the forming of the enamel extrac [...] | 0.410 |
| Prpf8 | Cwc25 | ENSMUSP00000018449 | ENSMUSP00000018685 | Pre-mRNA-processing-splicing factor 8; Plays role in pre-mRNA splicing as core component of precatalytic, catalytic and postcatalytic spliceosomal complexes, both of the predominant U2-type spliceosome and the minor U12-type spliceosome. Functions as a scaffold that mediates the ordered assembly of spliceosomal proteins and snRNAs. Required for the assembly of the U4/U6-U5 tri-snRNP complex, a building block of the spliceosome. Functions as scaffold that positions spliceosomal U2, U5 and U6 snRNAs at splice sites on pre-mRNA substrates, so that splicing can occur. Interacts with both t [...] | Pre-mRNA-splicing factor CWC25 homolog; Involved in pre-mRNA splicing as component of the spliceosome; Belongs to the CWC25 family. | 0.988 |
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