| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Grp | Nmbr | ENSMUSP00000025395 | ENSMUSP00000020015 | Gastrin-releasing peptide; Stimulates the release of gastrin and other gastrointestinal hormones (By similarity). Contributes to the perception of prurient stimuli and to the transmission of itch signals in the spinal cord that promote scratching behavior. Contributes primarily to nonhistaminergic itch sensation. Contributes to long-term fear memory, but not normal spatial memory. Contributes to the regulation of food intake. Belongs to the bombesin/neuromedin-B/ranatensin family. | Neuromedin-B receptor; Receptor for neuromedin-B; Belongs to the G-protein coupled receptor 1 family. | 0.982 |
| Grp | Nms | ENSMUSP00000025395 | ENSMUSP00000085346 | Gastrin-releasing peptide; Stimulates the release of gastrin and other gastrointestinal hormones (By similarity). Contributes to the perception of prurient stimuli and to the transmission of itch signals in the spinal cord that promote scratching behavior. Contributes primarily to nonhistaminergic itch sensation. Contributes to long-term fear memory, but not normal spatial memory. Contributes to the regulation of food intake. Belongs to the bombesin/neuromedin-B/ranatensin family. | Neuromedin-S; Implicated in the regulation of circadian rhythms through autocrine and/or paracrine actions; Belongs to the NmU family. | 0.791 |
| Grp | Nmu | ENSMUSP00000025395 | ENSMUSP00000031146 | Gastrin-releasing peptide; Stimulates the release of gastrin and other gastrointestinal hormones (By similarity). Contributes to the perception of prurient stimuli and to the transmission of itch signals in the spinal cord that promote scratching behavior. Contributes primarily to nonhistaminergic itch sensation. Contributes to long-term fear memory, but not normal spatial memory. Contributes to the regulation of food intake. Belongs to the bombesin/neuromedin-B/ranatensin family. | Neuromedin precursor-related peptide 33; [Neuromedin-U-23]: Ligand for receptors NMUR1 and NMUR2 (By similarity). Stimulates muscle contractions of specific regions of the gastrointestinal tract. [Neuromedin precursor-related peptide 36]: Does not function as a ligand for either NMUR1 or NMUR2. Indirectly induces prolactin release from lactotroph cells in the pituitary gland, probably via the hypothalamic dopaminergic system. | 0.568 |
| Grp | Nmur1 | ENSMUSP00000025395 | ENSMUSP00000148767 | Gastrin-releasing peptide; Stimulates the release of gastrin and other gastrointestinal hormones (By similarity). Contributes to the perception of prurient stimuli and to the transmission of itch signals in the spinal cord that promote scratching behavior. Contributes primarily to nonhistaminergic itch sensation. Contributes to long-term fear memory, but not normal spatial memory. Contributes to the regulation of food intake. Belongs to the bombesin/neuromedin-B/ranatensin family. | Neuromedin-U receptor 1; Receptor for the neuromedin-U and neuromedin-S neuropeptides. | 0.589 |
| Grp | Nmur2 | ENSMUSP00000025395 | ENSMUSP00000044718 | Gastrin-releasing peptide; Stimulates the release of gastrin and other gastrointestinal hormones (By similarity). Contributes to the perception of prurient stimuli and to the transmission of itch signals in the spinal cord that promote scratching behavior. Contributes primarily to nonhistaminergic itch sensation. Contributes to long-term fear memory, but not normal spatial memory. Contributes to the regulation of food intake. Belongs to the bombesin/neuromedin-B/ranatensin family. | Neuromedin-U receptor 2; Receptor for the neuromedin-U and neuromedin-S neuropeptides. | 0.725 |
| Grp | Nps | ENSMUSP00000025395 | ENSMUSP00000095597 | Gastrin-releasing peptide; Stimulates the release of gastrin and other gastrointestinal hormones (By similarity). Contributes to the perception of prurient stimuli and to the transmission of itch signals in the spinal cord that promote scratching behavior. Contributes primarily to nonhistaminergic itch sensation. Contributes to long-term fear memory, but not normal spatial memory. Contributes to the regulation of food intake. Belongs to the bombesin/neuromedin-B/ranatensin family. | Neuropeptide S; May play an important anorexigenic role. Modulates arousal and anxiety as well as increases locomotor activity. Binds to its receptor NPSR1 with nanomolar affinity to increase intracellular calcium concentrations. | 0.523 |
| Grp | Npy | ENSMUSP00000025395 | ENSMUSP00000031843 | Gastrin-releasing peptide; Stimulates the release of gastrin and other gastrointestinal hormones (By similarity). Contributes to the perception of prurient stimuli and to the transmission of itch signals in the spinal cord that promote scratching behavior. Contributes primarily to nonhistaminergic itch sensation. Contributes to long-term fear memory, but not normal spatial memory. Contributes to the regulation of food intake. Belongs to the bombesin/neuromedin-B/ranatensin family. | C-flanking peptide of NPY; NPY is implicated in the control of feeding and in secretion of gonadotrophin-release hormone; Belongs to the NPY family. | 0.632 |
| Grp | Prok2 | ENSMUSP00000025395 | ENSMUSP00000032152 | Gastrin-releasing peptide; Stimulates the release of gastrin and other gastrointestinal hormones (By similarity). Contributes to the perception of prurient stimuli and to the transmission of itch signals in the spinal cord that promote scratching behavior. Contributes primarily to nonhistaminergic itch sensation. Contributes to long-term fear memory, but not normal spatial memory. Contributes to the regulation of food intake. Belongs to the bombesin/neuromedin-B/ranatensin family. | Prokineticin-2; May function as an output molecule from the suprachiasmatic nucleus (SCN) that transmits behavioral circadian rhythm. May also function locally within the SCN to synchronize output. Potently contracts gastrointestinal (GI) smooth muscle (By similarity). Belongs to the AVIT (prokineticin) family. | 0.793 |
| Nmbr | Grp | ENSMUSP00000020015 | ENSMUSP00000025395 | Neuromedin-B receptor; Receptor for neuromedin-B; Belongs to the G-protein coupled receptor 1 family. | Gastrin-releasing peptide; Stimulates the release of gastrin and other gastrointestinal hormones (By similarity). Contributes to the perception of prurient stimuli and to the transmission of itch signals in the spinal cord that promote scratching behavior. Contributes primarily to nonhistaminergic itch sensation. Contributes to long-term fear memory, but not normal spatial memory. Contributes to the regulation of food intake. Belongs to the bombesin/neuromedin-B/ranatensin family. | 0.982 |
| Nmbr | Nms | ENSMUSP00000020015 | ENSMUSP00000085346 | Neuromedin-B receptor; Receptor for neuromedin-B; Belongs to the G-protein coupled receptor 1 family. | Neuromedin-S; Implicated in the regulation of circadian rhythms through autocrine and/or paracrine actions; Belongs to the NmU family. | 0.726 |
| Nmbr | Nmu | ENSMUSP00000020015 | ENSMUSP00000031146 | Neuromedin-B receptor; Receptor for neuromedin-B; Belongs to the G-protein coupled receptor 1 family. | Neuromedin precursor-related peptide 33; [Neuromedin-U-23]: Ligand for receptors NMUR1 and NMUR2 (By similarity). Stimulates muscle contractions of specific regions of the gastrointestinal tract. [Neuromedin precursor-related peptide 36]: Does not function as a ligand for either NMUR1 or NMUR2. Indirectly induces prolactin release from lactotroph cells in the pituitary gland, probably via the hypothalamic dopaminergic system. | 0.675 |
| Nmbr | Nmur1 | ENSMUSP00000020015 | ENSMUSP00000148767 | Neuromedin-B receptor; Receptor for neuromedin-B; Belongs to the G-protein coupled receptor 1 family. | Neuromedin-U receptor 1; Receptor for the neuromedin-U and neuromedin-S neuropeptides. | 0.514 |
| Nmbr | Nmur2 | ENSMUSP00000020015 | ENSMUSP00000044718 | Neuromedin-B receptor; Receptor for neuromedin-B; Belongs to the G-protein coupled receptor 1 family. | Neuromedin-U receptor 2; Receptor for the neuromedin-U and neuromedin-S neuropeptides. | 0.519 |
| Nmbr | Nps | ENSMUSP00000020015 | ENSMUSP00000095597 | Neuromedin-B receptor; Receptor for neuromedin-B; Belongs to the G-protein coupled receptor 1 family. | Neuropeptide S; May play an important anorexigenic role. Modulates arousal and anxiety as well as increases locomotor activity. Binds to its receptor NPSR1 with nanomolar affinity to increase intracellular calcium concentrations. | 0.609 |
| Nmbr | Prok2 | ENSMUSP00000020015 | ENSMUSP00000032152 | Neuromedin-B receptor; Receptor for neuromedin-B; Belongs to the G-protein coupled receptor 1 family. | Prokineticin-2; May function as an output molecule from the suprachiasmatic nucleus (SCN) that transmits behavioral circadian rhythm. May also function locally within the SCN to synchronize output. Potently contracts gastrointestinal (GI) smooth muscle (By similarity). Belongs to the AVIT (prokineticin) family. | 0.531 |
| Nms | Grp | ENSMUSP00000085346 | ENSMUSP00000025395 | Neuromedin-S; Implicated in the regulation of circadian rhythms through autocrine and/or paracrine actions; Belongs to the NmU family. | Gastrin-releasing peptide; Stimulates the release of gastrin and other gastrointestinal hormones (By similarity). Contributes to the perception of prurient stimuli and to the transmission of itch signals in the spinal cord that promote scratching behavior. Contributes primarily to nonhistaminergic itch sensation. Contributes to long-term fear memory, but not normal spatial memory. Contributes to the regulation of food intake. Belongs to the bombesin/neuromedin-B/ranatensin family. | 0.791 |
| Nms | Nmbr | ENSMUSP00000085346 | ENSMUSP00000020015 | Neuromedin-S; Implicated in the regulation of circadian rhythms through autocrine and/or paracrine actions; Belongs to the NmU family. | Neuromedin-B receptor; Receptor for neuromedin-B; Belongs to the G-protein coupled receptor 1 family. | 0.726 |
| Nms | Nmu | ENSMUSP00000085346 | ENSMUSP00000031146 | Neuromedin-S; Implicated in the regulation of circadian rhythms through autocrine and/or paracrine actions; Belongs to the NmU family. | Neuromedin precursor-related peptide 33; [Neuromedin-U-23]: Ligand for receptors NMUR1 and NMUR2 (By similarity). Stimulates muscle contractions of specific regions of the gastrointestinal tract. [Neuromedin precursor-related peptide 36]: Does not function as a ligand for either NMUR1 or NMUR2. Indirectly induces prolactin release from lactotroph cells in the pituitary gland, probably via the hypothalamic dopaminergic system. | 0.966 |
| Nms | Nmur1 | ENSMUSP00000085346 | ENSMUSP00000148767 | Neuromedin-S; Implicated in the regulation of circadian rhythms through autocrine and/or paracrine actions; Belongs to the NmU family. | Neuromedin-U receptor 1; Receptor for the neuromedin-U and neuromedin-S neuropeptides. | 0.992 |
| Nms | Nmur2 | ENSMUSP00000085346 | ENSMUSP00000044718 | Neuromedin-S; Implicated in the regulation of circadian rhythms through autocrine and/or paracrine actions; Belongs to the NmU family. | Neuromedin-U receptor 2; Receptor for the neuromedin-U and neuromedin-S neuropeptides. | 0.998 |
